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  1. Content type: Research article

    Regulatory approval of next generation sequencing (NGS) by the FDA is advancing the use of genomic-based precision medicine for the therapeutic management of cancer as standard care. Recent FDA guidance for th...

    Authors: Grace K. Dy, Mary K. Nesline, Antonios Papanicolau-Sengos, Paul DePietro, Charles M. LeVea, Amy Early, Hongbin Chen, Anne Grand’Maison, Patrick Boland, Marc S. Ernstoff, Stephen Edge, Stacey Akers, Mateusz Opyrchal, Gurkamal Chatta, Kunle Odunsi, Sarabjot Pabla…

    Citation: BMC Medical Informatics and Decision Making 2019 19:14

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  2. Content type: Research article

    Medication trend studies show the changes of medication over the years and may be replicated using a clinical Data Warehouse (CDW). Even nowadays, a lot of the patient information, like medication data, in the...

    Authors: Georg Dietrich, Jonathan Krebs, Leon Liman, Georg Fette, Maximilian Ertl, Mathias Kaspar, Stefan Störk and Frank Puppe

    Citation: BMC Medical Informatics and Decision Making 2019 19:15

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  3. Content type: Research article

    This paper suggests a method to assess the extent to which ultra-short Heart Rate Variability (HRV) features (less than 5 min) can be considered as valid surrogates of short HRV features (nominally 5 min). Sho...

    Authors: R. Castaldo, L. Montesinos, P. Melillo, C. James and L. Pecchia

    Citation: BMC Medical Informatics and Decision Making 2019 19:12

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  4. Content type: Research article

    Joint models (JM) have emerged as a promising statistical framework to concurrently analyse survival data and multiple longitudinal responses. This is particularly relevant in clinical studies where the goal i...

    Authors: Hugo Loureiro, Eunice Carrasquinha, Irina Alho, Arlindo R. Ferreira, Luís Costa, Alexandra M. Carvalho and Susana Vinga

    Citation: BMC Medical Informatics and Decision Making 2019 19:13

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  5. Content type: Research article

    With the growing shortage of nurses, labor-saving technology has become more important. In health care practice, however, the fit with innovations is not easy. The aim of this study is to analyze the developme...

    Authors: Danielle M. Vossebeld, Erik C. N. Puik, Joris E. N. Jaspers and Marieke J. Schuurmans

    Citation: BMC Medical Informatics and Decision Making 2019 19:11

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  6. Content type: Research article

    The health sector has quickly become a target for cyberattacks. Hospitals are especially sensitive to these sorts of attacks as any disruption in operations or even disclosure of patient personal information c...

    Authors: Salem T. Argaw, Nefti-Eboni Bempong, Bruce Eshaya-Chauvin and Antoine Flahault

    Citation: BMC Medical Informatics and Decision Making 2019 19:10

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  7. Content type: Research article

    Colorectal cancer (CRC) screening has shown to reduce incidence and mortality rates, and therefore is widely recommended for people above 50 years-old. However, despite the implementation of population-based s...

    Authors: Lilisbeth Perestelo-Perez, Amado Rivero-Santana, Alezandra Torres-Castaño, Vanesa Ramos-Garcia, Yolanda Alvarez-Perez, Nerea Gonzalez-Hernandez, Andrea Buron, Michael Pignone and Pedro Serrano-Aguilar

    Citation: BMC Medical Informatics and Decision Making 2019 19:8

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  8. Content type: Research article

    Adverse drug events (ADEs) as well as other preventable adverse events in the hospital setting incur a yearly monetary cost of approximately $3.5 billion, in the United States alone. Therefore, it is of paramo...

    Authors: Francesco Bagattini, Isak Karlsson, Jonathan Rebane and Panagiotis Papapetrou

    Citation: BMC Medical Informatics and Decision Making 2019 19:7

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  9. Content type: Software

    We developed Supportive care Prioritization, Assessment and Recommendations for Kids (SPARK), a web-based application designed to facilitate symptom screening by children receiving cancer treatments and access...

    Authors: Sadie Cook, Emily Vettese, Dilip Soman, Shannon Hyslop, Susan Kuczynski, Brenda Spiegler, Hailey Davis, Nathan Duong, Stacee Ou Wai, Robert Golabek, Patryk Golabek, Adam Antoszek-Rallo, Tal Schechter, L. Lee Dupuis and Lillian Sung

    Citation: BMC Medical Informatics and Decision Making 2019 19:9

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  10. Content type: Research article

    The Personal Patient Profile-Prostate (P3P) is a web-based decision support system for men newly diagnosed with localized prostate cancer that has demonstrated efficacy in reducing decisional conflict. Our obj...

    Authors: Leslie S. Wilson, Traci M. Blonquist, Fangxin Hong, Barbara Halpenny, Seth Wolpin, Peter Chang, Christopher P. Filson, Viraj A. Master, Martin G. Sanda, Gary W. Chien, Randy A. Jones, Tracey L. Krupski and Donna L. Berry

    Citation: BMC Medical Informatics and Decision Making 2019 19:6

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  11. Content type: Research article

    New Specific Application Domain (SAD) heuristics or design principles are being developed to guide the design and evaluation of mobile applications in a bid to improve on the usability of these applications. T...

    Authors: Alice Mugisha, Victoria Nankabirwa, Thorkild Tylleskär and Ankica Babic

    Citation: BMC Medical Informatics and Decision Making 2019 19:4

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  12. Content type: Research article

    Main adverse cardiac events (MACE) are essentially composite endpoints for assessing safety and efficacy of treatment processes of acute coronary syndrome (ACS) patients. Timely prediction of MACE is highly va...

    Authors: Huilong Duan, Zhoujian Sun, Wei Dong and Zhengxing Huang

    Citation: BMC Medical Informatics and Decision Making 2019 19:5

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  13. Content type: Research article

    Machine-learning classifiers mostly offer good predictive performance and are increasingly used to support shared decision-making in clinical practice. Focusing on performance and practicability, this study ev...

    Authors: Manuel Huber, Christoph Kurz and Reiner Leidl

    Citation: BMC Medical Informatics and Decision Making 2019 19:3

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  14. Content type: Research article

    The Cancer of the Prostate Risk Assessment (CAPRA) score was designed and validated several times to predict the biochemical recurrence-free survival after a radical prostatectomy. Our objectives were, first, ...

    Authors: Marine Lorent, Haïfa Maalmi, Philippe Tessier, Stéphane Supiot, Etienne Dantan and Yohann Foucher

    Citation: BMC Medical Informatics and Decision Making 2019 19:2

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  15. Content type: Research article

    Automatic clinical text classification is a natural language processing (NLP) technology that unlocks information embedded in clinical narratives. Machine learning approaches have been shown to be effective fo...

    Authors: Yanshan Wang, Sunghwan Sohn, Sijia Liu, Feichen Shen, Liwei Wang, Elizabeth J. Atkinson, Shreyasee Amin and Hongfang Liu

    Citation: BMC Medical Informatics and Decision Making 2019 19:1

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  16. Content type: Debate

    Nowadays, trendy research in biomedical sciences juxtaposes the term ‘precision’ to medicine and public health with companion words like big data, data science, and deep learning. Technological advancements pe...

    Authors: Mattia Prosperi, Jae S. Min, Jiang Bian and François Modave

    Citation: BMC Medical Informatics and Decision Making 2018 18:139

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  17. Content type: Research article

    A growing number of clinical trials use various sensors and smartphone applications to collect data outside of the clinic or hospital, raising the question to what extent patients comply with the unique requir...

    Authors: Shani Cohen, Zeev Waks, Jordan J. Elm, Mark Forrest Gordon, Igor D. Grachev, Leehee Navon-Perry, Shai Fine, Iris Grossman, Spyros Papapetropoulos and Juha-Matti Savola

    Citation: BMC Medical Informatics and Decision Making 2018 18:138

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  18. Content type: Research article

    Predicting progression from Mild Cognitive Impairment (MCI) to Alzheimer’s Disease (AD) is an utmost open issue in AD-related research. Neuropsychological assessment has proven to be useful in identifying MCI ...

    Authors: Telma Pereira, Francisco L. Ferreira, Sandra Cardoso, Dina Silva, Alexandre de Mendonça, Manuela Guerreiro and Sara C. Madeira

    Citation: BMC Medical Informatics and Decision Making 2018 18:137

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  19. Content type: Research article

    Hospitals have increasingly realized that wholesale adoption of electronic medical records (EMR) may introduce differential tangible/intangible benefits to them, including improved quality-of-care, reduced med...

    Authors: Kuang Ming Kuo, Yu Chang Chen, Paul C. Talley and Chi Hsien Huang

    Citation: BMC Medical Informatics and Decision Making 2018 18:135

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  20. Content type: Research article

    Physical inactivity is associated with poor health outcomes in chronic obstructive pulmonary disease (COPD). It is therefore crucial for patients to have a physically active lifestyle. The aims of this feasibilit...

    Authors: Tatjana M. Burkow, Lars K. Vognild, Elin Johnsen, Astrid Bratvold and Marijke Jongsma Risberg

    Citation: BMC Medical Informatics and Decision Making 2018 18:136

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  21. Content type: Research article

    Breast cancer chemoprevention can reduce breast cancer incidence in high-risk women; however, chemoprevention is underutilized in the primary care setting. We conducted a pilot study of decision support tools ...

    Authors: Rita Kukafka, Jiaqi Fang, Alejandro Vanegas, Thomas Silverman and Katherine D. Crew

    Citation: BMC Medical Informatics and Decision Making 2018 18:134

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  22. Content type: Research article

    Proper logistics management information system in the supply chain improves health outcomes by maintaining accurate and timely information. The purpose of this study was to determine program drugs logistics ma...

    Authors: Kefyalewu Tiye and Tadesse Gudeta

    Citation: BMC Medical Informatics and Decision Making 2018 18:133

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  23. Content type: Research article

    Decision-making about palliative care for metastatic colorectal cancer (mCRC) consists of many different treatment-related decisions, and there generally is no best treatment option. Decision support systems (...

    Authors: Ellen G. Engelhardt, Dóra Révész, Hans J. Tamminga, Cornelis J. A. Punt, Miriam Koopman, Bregje D. Onwuteaka-Philipsen, Ewout W. Steyerberg, Henrica C. W. de Vet and Veerle M. H. Coupé

    Citation: BMC Medical Informatics and Decision Making 2018 18:132

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  24. Content type: Research

    Access to palliative care is a key quality metric which most healthcare organizations strive to improve. The primary challenges to increasing palliative care access are a combination of physicians over-estimat...

    Authors: Anand Avati, Kenneth Jung, Stephanie Harman, Lance Downing, Andrew Ng and Nigam H. Shah

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 4):122

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    This article is part of a Supplement: Volume 18 Supplement 4

  25. Content type: Research

    There has been an increasing interest in understanding the usefulness of wrist-based accelerometer data for physical activity (PA) assessment due to the ease of use and higher user compliance than other body p...

    Authors: Matin Kheirkhahan, Avirup Chakraborty, Amal A. Wanigatunga, Duane B. Corbett, Todd M. Manini and Sanjay Ranka

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 4):124

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    This article is part of a Supplement: Volume 18 Supplement 4

  26. Content type: Research

    Chronic Kidney Disease (CKD) is one of several conditions that affect a growing percentage of the US population; the disease is accompanied by multiple co-morbidities, and is hard to diagnose in-and-of itself. In...

    Authors: Moumita Bhattacharya, Claudine Jurkovitz and Hagit Shatkay

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 4):125

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    This article is part of a Supplement: Volume 18 Supplement 4

  27. Content type: Research

    There has been an increasing interest in learning low-dimensional vector representations of medical concepts from Electronic Health Records (EHRs). Vector representations of medical concepts facilitate explora...

    Authors: Tian Bai, Ashis Kumar Chanda, Brian L. Egleston and Slobodan Vucetic

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 4):123

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    This article is part of a Supplement: Volume 18 Supplement 4

  28. Content type: Research article

    Systems science methods such as dynamic simulation modelling are well suited to address questions about public health policy as they consider the complexity, context and dynamic nature of system-wide behaviour...

    Authors: Louise Freebairn, Jo-An Atkinson, Paul M. Kelly, Geoff McDonnell and Lucie Rychetnik

    Citation: BMC Medical Informatics and Decision Making 2018 18:131

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  29. Content type: Research

    SNOMED CT is a standardized and comprehensive clinical terminology that is used in Electronic Health Records to capture, store and access clinical data of patients. Studies have, however, shown that there are ...

    Authors: Ankur Agrawal

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 4):88

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    This article is part of a Supplement: Volume 18 Supplement 4

  30. Content type: Research

    Accurate predictive modeling in clinical research enables effective early intervention that patients are most likely to benefit from. However, due to the complex biological nature of disease progression, captu...

    Authors: Xiangrui Li, Dongxiao Zhu and Phillip Levy

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 4):126

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    This article is part of a Supplement: Volume 18 Supplement 4

  31. Content type: Research

    Although gastric cancer is a malignancy with high morbidity and mortality in China, the survival rate of patients with early gastric cancer (EGC) is high after surgical resection. To strengthen diagnosing and ...

    Authors: Mi-Mi Liu, Li Wen, Yong-Jia Liu, Qiao Cai, Li-Ting Li and Yong-Ming Cai

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):121

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    This article is part of a Supplement: Volume 18 Supplement 5

  32. Content type: Research article

    The use of health information technology (HIT) to improve patient safety is widely advocated by governmental and safety agencies. Electronic-prescribing and smart-pump technology are examples of HIT medication...

    Authors: Moninne M. Howlett, Brian J. Cleary and Cormac V. Breatnach

    Citation: BMC Medical Informatics and Decision Making 2018 18:130

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  33. Content type: Research

    Automated seizure detection from clinical EEG data can reduce the diagnosis time and facilitate targeting treatment for epileptic patients. However, current detection approaches mainly rely on limited features...

    Authors: Xiaoyan Wei, Lin Zhou, Ziyi Chen, Liangjun Zhang and Yi Zhou

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):111

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    This article is part of a Supplement: Volume 18 Supplement 5

  34. Content type: Research

    Health professionals and consumers use different terms to express medical events or concerns, which makes the communication barriers between the professionals and consumers. This may lead to bias in the diagno...

    Authors: Li Hou, Hongyu Kang, Yan Liu, Luqi Li and Jiao Li

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):120

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    This article is part of a Supplement: Volume 18 Supplement 5

  35. Content type: Research

    Patient falls, the most common safety events resulting in adverse patient outcomes, impose significant costs and have become a great burden to the healthcare community. Current patient fall reporting systems r...

    Authors: Hong Kang, Sicheng Zhou, Bin Yao and Yang Gong

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):110

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    This article is part of a Supplement: Volume 18 Supplement 5

  36. Content type: Research

    The application of artificial intelligence techniques for processing electronic health records data plays increasingly significant role in advancing clinical decision support. This study conducts a quantitativ...

    Authors: Xieling Chen, Ziqing Liu, Li Wei, Jun Yan, Tianyong Hao and Ruoyao Ding

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):117

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    This article is part of a Supplement: Volume 18 Supplement 5

  37. Content type: Research

    Medication events in clinical settings are significant threats to patient safety. Analyzing and learning from the medication event reports is an important way to prevent the recurrence of these events. Current...

    Authors: Sicheng Zhou, Hong Kang, Bin Yao and Yang Gong

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):113

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    This article is part of a Supplement: Volume 18 Supplement 5

  38. Content type: Research

    Disease named entity recognition (NER) is a fundamental step in information processing of medical texts. However, disease NER involves complex issues such as descriptive modifiers in actual practice. The accur...

    Authors: Kai Xu, Zhanfan Zhou, Tao Gong, Tianyong Hao and Wenyin Liu

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):114

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    This article is part of a Supplement: Volume 18 Supplement 5

  39. Content type: Research

    To realize semantic interoperability for Primary Health Information System (PHIS), this study analyzes and applies existing health information data standards in China. This research aims to establish a Primary...

    Authors: Xia Zhao, Xiaohua Li, Wei Yang, Qianjin Feng, Yi Zhou and Qiong Wang

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):112

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    This article is part of a Supplement: Volume 18 Supplement 5

  40. Content type: Research

    Data heterogeneity is a common phenomenon related to the secondary use of electronic health records (EHR) data from different sources. The Observational Health Data Sciences and Informatics (OHDSI) Common Data...

    Authors: Na Hong, Ning Zhang, Huawei Wu, Shanshan Lu, Yue Yu, Li Hou, Yinying Lu, Hongfang Liu and Guoqian Jiang

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):116

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 5

  41. Content type: Research

    Colorectal Cancer (CRC) is the third leading cause of cancer death among men and women in the United States. Research has shown that the risk of CRC associates with genetic and lifestyle factors. It is possibl...

    Authors: Jiannan Liu, Chenyang Li, Jing Xu and Huanmei Wu

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):118

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    This article is part of a Supplement: Volume 18 Supplement 5

  42. Content type: Research

    Feature selection and gene set analysis are of increasing interest in the field of bioinformatics. While these two approaches have been developed for different purposes, we describe how some gene set analysis ...

    Authors: Suyan Tian, Chi Wang and Howard H. Chang

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):115

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 5

  43. Content type: Research

    The Gene Ontology (GO) is a resource that supplies information about gene product function using ontologies to represent biological knowledge. These ontologies cover three domains: Cellular Component (CC), Mol...

    Authors: Ruoyao Ding, Yingying Qu, Cathy H. Wu and K. Vijay-Shanker

    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 5):119

    Published on:

    This article is part of a Supplement: Volume 18 Supplement 5

  44. Content type: Technical advance

    As of 2014, stroke is the fourth leading cause of death in Japan. Predicting a future diagnosis of stroke would better enable proactive forms of healthcare measures to be taken. We aim to predict a diagnosis o...

    Authors: Douglas Teoh

    Citation: BMC Medical Informatics and Decision Making 2018 18:127

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  45. Content type: Research article

    Extracting primary care information in terms of Patient/Problem, Intervention, Comparison and Outcome, known as PICO elements, is difficult as the volume of medical information expands and the health semantics...

    Authors: Samir Chabou and Michal Iglewski

    Citation: BMC Medical Informatics and Decision Making 2018 18:128

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  46. Content type: Research article

    Colorectal cancer incidence and mortality have been increasing in China and as one of the most important health problems facing the nation. Adequate dissemination of correct information about colorectal cancer...

    Authors: Shun Zhang, Yao Yang, Dongyi Yan, Biao Yuan, Xiaohua Jiang and Chun Song

    Citation: BMC Medical Informatics and Decision Making 2018 18:129

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  47. Content type: Research article

    With advancements in information technology, computerized physician order entry (CPOE) and electronic Medical Records (eMR), have become widely utilized in medical settings. The predominant mode of CPOE in Tai...

    Authors: George Linn, Yung-Hsiang Ying and Koyin Chang

    Citation: BMC Medical Informatics and Decision Making 2018 18:109

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  48. Content type: Research article

    Patient portal use can be a stimulant for patient engagement. Yet, the heterogeneous landscape of tethered patient portals, is a major barrier to further portal development and implementation. A variety in por...

    Authors: Gaby Anne Wildenbos, Frank Horenberg, Monique Jaspers, Linda Peute and Danielle Sent

    Citation: BMC Medical Informatics and Decision Making 2018 18:108

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  49. Content type: Research article

    The decreasing cost of obtaining high-quality calls of genomic variants and the increasing availability of clinically relevant data on such variants are important drivers for personalized oncology. To allow ra...

    Authors: Johannes Starlinger, Steffen Pallarz, Jurica Ševa, Damian Rieke, Christine Sers, Ulrich Keilholz and Ulf Leser

    Citation: BMC Medical Informatics and Decision Making 2018 18:107

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  50. Content type: Study protocol

    Longevity creates increasing care needs for healthcare providers and family caregivers. Increasingly, the burden of care falls to one primary caregiver, increasing stress and reducing health outcomes. Addition...

    Authors: Yuri Quintana, Bradley Crotty, Darren Fahy, Lewis Lipsitz, Roger B. Davis and Charles Safran

    Citation: BMC Medical Informatics and Decision Making 2018 18:105

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