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  1. Gene expression data play an important role in bioinformatics applications. Although there may be a large number of features in such data, they mainly tend to contain only a few samples. This can negatively im...

    Authors: Saeid Azadifar and Ali Ahmadi

    Citation: BMC Medical Informatics and Decision Making 2021 21:333

    Content type: Research

    Published on:

  2. An increase in the incidence of central venous catheter (CVC)-associated deep venous thrombosis (CADVT) has been reported in pediatric patients over the past decade. At the same time, current screening guideli...

    Authors: Haomin Li, Yang Lu, Xian Zeng, Cangcang Fu, Huilong Duan, Qiang Shu and Jihua Zhu

    Citation: BMC Medical Informatics and Decision Making 2021 21:332

    Content type: Research

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  3. Buprenorphine is a widely used treatment option for patients with opioid use disorder (OUD). Premature discontinuation from this treatment has many negative health and societal consequences.

    Authors: Md Mahmudul Hasan, Gary J. Young, Jiesheng Shi, Prathamesh Mohite, Leonard D. Young, Scott G. Weiner and Md. Noor-E-Alam

    Citation: BMC Medical Informatics and Decision Making 2021 21:331

    Content type: Research

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  4. Prostate cancer (PCa) is the leading male neoplasm in South Africa with an age-standardised incidence rate of 68.0 per 100,000 population in 2018. The Gleason score (GS) is the strongest predictive factor for ...

    Authors: Naseem Cassim, Michael Mapundu, Victor Olago, Turgay Celik, Jaya Anna George and Deborah Kim Glencross

    Citation: BMC Medical Informatics and Decision Making 2021 21:330

    Content type: Research

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  5. To improve chronic disease outcomes, self-management is an effective strategy. An electronic personal health record (ePHR) is a promising tool with the potential to support chronic patient’s education, counsel...

    Authors: Esmaeel Toni, Habibollah Pirnejad, Khadijeh Makhdoomi, Azam Mivefroshan and Zahra Niazkhani

    Citation: BMC Medical Informatics and Decision Making 2021 21:329

    Content type: Research

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  6. In surgical department, CPT code assignment has been a complicated manual human effort, that entails significant related knowledge and experience. While there are several studies using CPTs to make predictions...

    Authors: Tannaz Khaleghi, Alper Murat and Suzan Arslanturk

    Citation: BMC Medical Informatics and Decision Making 2021 21:328

    Content type: Research

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  7. Due to the importance of segmentation of MRI images in identifying brain tumors, various methods including deep learning have been introduced for automatic brain tumor segmentation. On the other hand, using a ...

    Authors: Mohamadreza Hajiabadi, Behrouz Alizadeh Savareh, Hassan Emami and Azadeh Bashiri

    Citation: BMC Medical Informatics and Decision Making 2021 21:327

    Content type: Research

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  8. Quality data from Health Management Information Systems (HMIS) are important for tracking the effectiveness of malaria control interventions. However, HMIS data in many resource-limited settings do not current...

    Authors: Azoukalné Moukénet, Monica Anna de Cola, Charlotte Ward, Honoré Beakgoubé, Kevin Baker, Laura Donovan, Jean Laoukolé and Sol Richardson

    Citation: BMC Medical Informatics and Decision Making 2021 21:326

    Content type: Research

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  9. Patients with chronic obstructive pulmonary disease (COPD) experience deficits in exercise capacity and physical activity as their disease progresses. Pulmonary rehabilitation (PR) can enhance exercise capacit...

    Authors: Ning Deng, Leiyi Sheng, Wangshu Jiang, Yongfa Hao, Shuoshuo Wei, Bei Wang, Huilong Duan and Juan Chen

    Citation: BMC Medical Informatics and Decision Making 2021 21:325

    Content type: Research

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  11. MyDiabetesPlan is a web-based, interactive patient decision aid that facilitates patient-centred, diabetes-specific, goal-setting and shared decision-making (SDM) with interprofessional health care teams.

    Authors: Catherine H. Yu, Farid Medleg, Dorothy Choi, Catherine M. Spagnuolo, Lakmini Pinnaduwage, Sharon E. Straus, Paul Cantarutti, Karen Chu, Paul Frydrych, Amy Hoang-Kim, Noah Ivers, David Kaplan, Fok-Han Leung, John Maxted, Jeremy Rezmovitz, Joanna Sale…

    Citation: BMC Medical Informatics and Decision Making 2021 21:323

    Content type: Research

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  12. While random forests are one of the most successful machine learning methods, it is necessary to optimize their performance for use with datasets resulting from a two-phase sampling design with a small number ...

    Authors: Sunwoo Han, Brian D. Williamson and Youyi Fong

    Citation: BMC Medical Informatics and Decision Making 2021 21:322

    Content type: Research article

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  13. Cardiovascular diseases (CVDs) are always considered by healthcare specialists for different reasons, including extensive prevalence, increased costs, chronicity, and high risk of death. The control of CVDs is...

    Authors: Atiyeh Saboktakin, Mohammad Mehdi Sepehri and Roghaye Khasha

    Citation: BMC Medical Informatics and Decision Making 2021 21:321

    Content type: Research article

    Published on:

  14. As the vast majority of women who present in threatened preterm labour (TPTL) will not deliver early, clinicians need to balance the risks of over-medicalising the majority of women, against the potential risk...

    Authors: N. Carlisle, H. A. Watson, J. Carter, K. Kuhrt, P. T. Seed, R. M. Tribe, J. Sandall and A. H. Shennan

    Citation: BMC Medical Informatics and Decision Making 2021 21:320

    Content type: Research article

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  15. A large number of biological studies have shown that miRNAs are inextricably linked to many complex diseases. Studying the miRNA-disease associations could provide us a root cause understanding of the underlyi...

    Authors: Shanchen Pang, Yu Zhuang, Xinzeng Wang, Fuyu Wang and Sibo Qiao

    Citation: BMC Medical Informatics and Decision Making 2021 21:319

    Content type: Research

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  16. Inadequate assessment of the severity and urgency of health problems is one of the factors contributing to unnecessary emergency department visits. A software-based instrument for standardized initial assessme...

    Authors: Amanda Breckner, Catharina Roth, Joachim Szecsenyi and Michel Wensing

    Citation: BMC Medical Informatics and Decision Making 2021 21:318

    Content type: Research

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  17. A lot of medical mentions can be extracted from a huge amount of medical texts. In order to make use of these medical mentions, a prerequisite step is to link those medical mentions to a medical domain knowled...

    Authors: Cheng Yan, Yuanzhe Zhang, Kang Liu, Jun Zhao, Yafei Shi and Shengping Liu

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):317

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  18. We aimed to build a common terminology in the domain of cervical cancer, named Cervical Cancer Common Terminology (CCCT), that will facilitate clinical data exchange, ensure quality of data and support large s...

    Authors: Na Hong, Fengxiang Chang, Zhengjie Ou, Yishang Wang, Yating Yang, Qiang Guo, Jianhui Ma and Dan Zhao

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):309

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  19. The historical data of rare disease is very scarce in reality, so how to perform drug repositioning for the rare disease is a great challenge. Most existing methods of drug repositioning for the rare disease u...

    Authors: Hongkui Cao, Liang Zhang, Bo Jin, Shicheng Cheng, Xiaopeng Wei and Chao Che

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):304

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  20. To meet the needs of aging and dementia patients in Taiwan, this study designed a nursing system that includes communication, location tracking, and fall detection, and early warning services. The main purpose...

    Authors: Cheng-Wen Lee and Hsiu-Mang Chuang

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 10):273

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 10

  21. 2019-nCoV has been spreading around the world and becoming a global concern. To prevent further widespread of 2019-nCoV, confirmed and suspected cases of COVID-19 infection are suggested to be kept in quaranti...

    Authors: Huanhuan Wu, Yichen Zhong, Yingjie Tian, Shan Jiang and Lingyun Luo

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):271

    Content type: Methodology

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  22. In recent years, with the development of artificial intelligence, the use of deep learning technology for clinical information extraction has become a new trend. Clinical Event Detection (CED) as its subtask h...

    Authors: Zhichang Zhang, Dan Liu, Minyu Zhang and Xiaohui Qin

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):261

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  23. Clinical notes are unstructured text documents generated by clinicians during patient encounters, generally are annotated with International Classification of Diseases (ICD) codes, which give formatted informa...

    Authors: Shuyuan Hu, Fei Teng, Lufei Huang, Jun Yan and Haibo Zhang

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):256

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  24. Drug repurposing is to find new indications of approved drugs, which is essential for investigating new uses for approved or investigational drug efficiency. The active gene annotation corpus (named AGAC) is a...

    Authors: Dongfang Li, Ying Xiong, Baotian Hu, Buzhou Tang, Weihua Peng and Qingcai Chen

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):251

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  25. Standardized coding of plays an important role in radiology reports’ secondary use such as data analytics, data-driven decision support, and personalized medicine. RadLex, a standard radiological lexicon, can ...

    Authors: Yani Chen, Shan Nan, Qi Tian, Hailing Cai, Huilong Duan and Xudong Lu

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):247

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 9

  27. Electronic medical records are widely used in family practices across Canada and can improve health outcomes. However, recent reports indicate that physicians using electronic medical records work longer and h...

    Authors: Scott Laing and Jay Mercer

    Citation: BMC Medical Informatics and Decision Making 2021 21:315

    Content type: Research

    Published on:

  28. In Japan, the number of older people with various health problems and difficulties in living is increasing. In order to practice patient-centered care for them, not only medical professionals but also multidis...

    Authors: Yuko Goto, Yasuhiro Yamaguchi, Joji Onishi, Hidenori Arai, Martin Härter, Isabelle Scholl, Levente Kriston and Hisayuki Miura

    Citation: BMC Medical Informatics and Decision Making 2021 21:314

    Content type: Research

    Published on:

  29. Several hematological indices have been already proposed to discriminate between iron deficiency anemia (IDA) and β‐thalassemia trait (βTT). This study compared the diagnostic performance of different hematolo...

    Authors: Fakher Rahim, Anoshirvan Kazemnejad, Mina Jahangiri, Amal Saki Malehi and Kimiya Gohari

    Citation: BMC Medical Informatics and Decision Making 2021 21:313

    Content type: Research

    Published on:

  30. Diagnosis-related groups (DRGs) are a payment system that could effectively solve the problem of excessive increases in healthcare costs which are applied as a principal measure in the healthcare reform in Chi...

    Authors: Xiaoting Liu, Chenhao Fang, Chao Wu, Jianxing Yu and Qi Zhao

    Citation: BMC Medical Informatics and Decision Making 2021 21:312

    Content type: Research

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  31. The new International Classification of Diseases—11th revision (ICD-11) succeeds ICD-10. In the three decades since ICD-10 was released, demands for detailed information on the clinical history of a morbid pat...

    Authors: Saskia E. Drösler, Stefanie Weber and Christopher G. Chute

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 6):278

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 6

  32. Fast food with its abundance and availability to consumers may have health consequences due to the high calorie intake which is a major contributor to life threatening diseases. Providing nutritional informati...

    Authors: Muhammad Amith, Chidinma Onye, Tracey Ledoux, Grace Xiong and Cui Tao

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 7):275

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  33. There are significant variabilities in guideline-concordant documentation in asthma care. However, assessing clinician’s documentation is not feasible using only structured data but requires labor-intensive ch...

    Authors: Bhavani Singh Agnikula Kshatriya, Elham Sagheb, Chung-Il Wi, Jungwon Yoon, Hee Yun Seol, Young Juhn and Sunghwan Sohn

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 7):272

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  34. As biomedical knowledge is rapidly evolving, concept enrichment of biomedical terminologies is an active research area involving automatic identification of missing or new concepts. Previously, we prototyped a...

    Authors: Fengbo Zheng, Rashmie Abeysinghe and Licong Cui

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 7):234

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 7

  35. The International Classification of Diseases (ICD) has long been the main basis for comparability of statistics on causes of mortality and morbidity between places and over time. This paper provides an overvie...

    Authors: James E. Harrison, Stefanie Weber, Robert Jakob and Christopher G. Chute

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 6):206

    Content type: Review

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 6

  36. Interpretation of chest radiographs (CRs) by emergency department (ED) physicians is inferior to that by radiologists. Recent studies have investigated the effect of deep learning-based assistive technology on...

    Authors: Ji Hoon Kim, Sang Gil Han, Ara Cho, Hye Jung Shin and Song-Ee Baek

    Citation: BMC Medical Informatics and Decision Making 2021 21:311

    Content type: Research

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  37. A subgroup of patients with asthma has been reported to have an increased risk for asthma-associated infectious and inflammatory multimorbidities (AIMs). To systematically investigate the association of asthma...

    Authors: Jungwon Yoon, Heather Billings, Chung-Il Wi, Elissa Hall, Sunghwan Sohn, Jung Hyun Kwon, Euijung Ryu, Pragya Shrestha, Hongfang Liu and Young J. Juhn

    Citation: BMC Medical Informatics and Decision Making 2021 21:310

    Content type: Research article

    Published on:

  38. Disease-drug associations provide essential information for drug discovery and disease treatment. Many disease-drug associations remain unobserved or unknown, and trials to confirm these associations are time-...

    Authors: Pengwei Hu, Yu-an Huang, Jing Mei, Henry Leung, Zhan-heng Chen, Ze-min Kuang, Zhu-hong You and Lun Hu

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 1):308

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 1

  39. Medication reconciliation (MedRec), a process to reduce medication error at care transitions, is labour- and resource-intensive and time-consuming. Use of Personal Electronic Records of Medications (PERMs) in ...

    Authors: Catherine Waldron, Joan Cahill, Sam Cromie, Tim Delaney, Sean P. Kennelly, Joshua M. Pevnick and Tamasine Grimes

    Citation: BMC Medical Informatics and Decision Making 2021 21:307

    Content type: Research

    Published on:

  40. In resources constrained settings, effectively implemented Electronic Medical Record systems have numerous benefits over paper-based record keeping. This system was implemented in the 2009 Gregorian Calendar i...

    Authors: Alemayehu Bisrat, Dagne Minda, Bekalu Assamnew, Biruk Abebe and Teshome Abegaz

    Citation: BMC Medical Informatics and Decision Making 2021 21:306

    Content type: Research article

    Published on:

  42. Early identification of the occurrence of arrhythmia in patients with acute myocardial infarction plays an essential role in clinical decision-making. The present study attempted to use machine learning (ML) m...

    Authors: Suhuai Wang, Jingjie Li, Lin Sun, Jianing Cai, Shihui Wang, Linwen Zeng and Shaoqing Sun

    Citation: BMC Medical Informatics and Decision Making 2021 21:301

    Content type: Research

    Published on:

  43. Accurately predicting which patients with chronic heart failure (CHF) are particularly vulnerable for adverse outcomes is of crucial importance to support clinical decision making. The goal of the current stud...

    Authors: Onno P. van der Galiën, René C. Hoekstra, Muhammed T. Gürgöze, Olivier C. Manintveld, Mark R. van den Bunt, Cor J. Veenman and Eric Boersma

    Citation: BMC Medical Informatics and Decision Making 2021 21:303

    Content type: Research

    Published on:

  44. Data quality assessment is important but complex and task dependent. Identifying suitable measurement methods and reference ranges for assessing their results is challenging. Manually inspecting the measuremen...

    Authors: Erik Tute, Nagarajan Ganapathy and Antje Wulff

    Citation: BMC Medical Informatics and Decision Making 2021 21:302

    Content type: Research

    Published on:

  45. Computer-aided diagnosis (CAD) systems based on medical images could support physicians in the decision-making process. During the last decades, researchers have proposed CAD systems in several medical domains...

    Authors: Giacomo Donato Cascarano, Francesco Saverio Debitonto, Ruggero Lemma, Antonio Brunetti, Domenico Buongiorno, Irio De Feudis, Andrea Guerriero, Umberto Venere, Silvia Matino, Maria Teresa Rocchetti, Michele Rossini, Francesco Pesce, Loreto Gesualdo and Vitoantonio Bevilacqua

    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 1):300

    Content type: Research

    Published on:

    This article is part of a Supplement: Volume 21 Supplement 1

  46. Self-care and participation of patients in improving health and increasing awareness about the risk factors that affect the development of disease in patients with urinary tract stones are influential factors ...

    Authors: Leila Shahmoradi, Amin Azizpour, Mahmud Bejani, Pejman Shadpour and Sorayya Rezayi

    Citation: BMC Medical Informatics and Decision Making 2021 21:299

    Content type: Research

    Published on:

  47. Prediction of length of stay (LOS) at admission time can provide physicians and nurses insight into the illness severity of patients and aid them in avoiding adverse events and clinical deterioration. It also ...

    Authors: Amin Naemi, Thomas Schmidt, Marjan Mansourvar, Ali Ebrahimi and Uffe Kock Wiil

    Citation: BMC Medical Informatics and Decision Making 2021 21:298

    Content type: Research

    Published on:

  48. The use of general practice electronic health records (EHRs) for research purposes is in its infancy in Australia. Given these data were collected for clinical purposes, questions remain around data quality an...

    Authors: Sharmala Thuraisingam, Patty Chondros, Michelle M. Dowsey, Tim Spelman, Stephanie Garies, Peter F. Choong, Jane Gunn and Jo-Anne Manski-Nankervis

    Citation: BMC Medical Informatics and Decision Making 2021 21:297

    Content type: Research

    Published on:

  49. Healthcare organizations have begun to adopt personal health records (PHR) systems to engage patients, but little is known about factors associated with the adoption of PHR systems at an organizational level. ...

    Authors: Byung Kwan Choi, Young-Taek Park, Hyeoun-Ae Park, Chris Lane, Emmanuel C. Jo and Sunghong Kang

    Citation: BMC Medical Informatics and Decision Making 2021 21:296

    Content type: Research article

    Published on:

  50. Occlusions of intravenous (IV) tubing can prevent vital and time-critical medication or solutions from being delivered into the bloodstream of patients receiving IV therapy. At low flow rates (≤ 1 ml/h) the al...

    Authors: Frank Doesburg, Roy Oelen, Maurits H. Renes, Pedro M. Lourenço, Daan J. Touw and Maarten W. Nijsten

    Citation: BMC Medical Informatics and Decision Making 2021 21:295

    Content type: Research

    Published on:

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