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  1. For liver cancer patients, the occurrence of postoperative complications increases the difficulty of perioperative nursing, prolongs the hospitalization time of patients, and leads to large increases in hospit...

    Authors: Siyu Zeng, Lele Li, Yanjie Hu, Li Luo and Yuanchen Fang
    Citation: BMC Medical Informatics and Decision Making 2021 21:371
  2. Currently, numerous antihypertensive drugs from different pharmacological classes are available; however, blood pressure control is achieved in only less than a third of patients treated for hypertension. More...

    Authors: Chunyu Liu, Jing Xu, Ran Liu, Miye Wang, Yixuan Zhuo, Lan Su, Hongmei Yan and Qing Zhang
    Citation: BMC Medical Informatics and Decision Making 2021 21:370
  3. Relation extraction (RE) is a fundamental task of natural language processing, which always draws plenty of attention from researchers, especially RE at the document-level. We aim to explore an effective novel...

    Authors: Tao Li, Ying Xiong, Xiaolong Wang, Qingcai Chen and Buzhou Tang
    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 7):368

    This article is part of a Supplement: Volume 21 Supplement 7

  4. The International Classification of Functioning, Disability and Health (ICF) is a classification of health and health-related states developed by the World Health Organization (WHO) to provide a standard and u...

    Authors: Silvia Cozzi, Andrea Martinuzzi and Vincenzo Della Mea
    Citation: BMC Medical Informatics and Decision Making 2021 21:367
  5. Digital health technologies can support primary care delivery, but clinical uptake in primary care is limited. This study explores enablers and barriers experienced by primary care providers when adopting new ...

    Authors: Hardeep Singh, Farah Tahsin, Jason Xin Nie, Brian McKinstry, Kednapa Thavorn, Ross Upshur, Sarah Harvey, Walter P. Wodchis and Carolyn Steele Gray
    Citation: BMC Medical Informatics and Decision Making 2021 21:366
  6. Currently, cardiovascular disease has become a major disease endangering human health, and the number of such patients is growing. Electrocardiogram (ECG) is an important basis for {medical doctors to diagnose...

    Authors: Jinyong Cheng, Qingxu Zou and Yunxiang Zhao
    Citation: BMC Medical Informatics and Decision Making 2021 21:365
  7. Rapid and irregular ventricular rates (RVR) are an important consequence of atrial fibrillation (AF). Raw accelerometry data in combination with electrocardiogram (ECG) data have the potential to distinguish i...

    Authors: Zhi Li, Kevin M. Wheelock, Sangeeta Lathkar-Pradhan, Hakan Oral, Daniel J. Clauw, Pujitha Gunaratne, Jonathan Gryak, Kayvan Najarian, Brahmajee K. Nallamothu and Hamid Ghanbari
    Citation: BMC Medical Informatics and Decision Making 2021 21:364
  8. Electronic medical records systems (EMRs) adoption in healthcare to facilitate work processes have become common in many countries. Although EMRs are associated with quality patient care, patient safety, and c...

    Authors: Philomena N. Ngugi, Martin C. Were and Ankica Babic
    Citation: BMC Medical Informatics and Decision Making 2021 21:362
  9. Mood disorders (MDS) are a type of mental health illness that effects millions of people in the United States. Early prediction of MDS can give providers greater opportunity to treat these disorders. We hypoth...

    Authors: Aixia Guo, Kari A. Stephens, Yosef M. Khan, James R. Langabeer and Randi E. Foraker
    Citation: BMC Medical Informatics and Decision Making 2021 21:361
  10. Numerous pieces of clinical evidence have shown that many phenotypic traits of human disease are related to their gut microbiome, i.e., inflammation, obesity, HIV, and diabetes. Through supervised classificati...

    Authors: Jiayu Zhou, Yanqing Ye and Jiang Jiang
    Citation: BMC Medical Informatics and Decision Making 2021 21:360
  11. Nowadays, various simulation approaches for evaluation and decision making in cancer screening can be found in the literature. This paper presents an overview of approaches used to assess screening programs fo...

    Authors: Aleksandr Bespalov, Anton Barchuk, Anssi Auvinen and Jaakko Nevalainen
    Citation: BMC Medical Informatics and Decision Making 2021 21:359
  12. Extensive sequencing of tumor tissues has greatly improved our understanding of cancer biology over the past years. The integration of genomic and clinical data is increasingly used to select personalized ther...

    Authors: Arsenij Ustjanzew, Alexander Desuki, Christoph Ritzel, Alina Corinna Dolezilek, Daniel-Christoph Wagner, Jan Christoph, Philipp Unberath, Thomas Kindler, Jörg Faber, Federico Marini, Torsten Panholzer and Claudia Paret
    Citation: BMC Medical Informatics and Decision Making 2021 21:358
  13. Loss to follow-up (LFTU) among HIV patients remains a major obstacle to achieving treatment goals with the risk of failure to achieve viral suppression and thereby increased HIV transmission. Although use of c...

    Authors: Tom Oluoch, Ronald Cornet, Jacques Muthusi, Abraham Katana, Davies Kimanga, Daniel Kwaro, Nicky Okeyo, Ameen Abu-Hanna and Nicolette de Keizer
    Citation: BMC Medical Informatics and Decision Making 2021 21:357
  14. Data-driven process analysis is an important area that relies on software support. Process variant analysis is a sort of analysis technique in which analysts compare executed process variants, a.k.a. process c...

    Authors: Amin Jalali, Paul Johannesson, Erik Perjons, Ylva Askfors, Abdolazim Rezaei Kalladj, Tero Shemeikka and Anikó Vég
    Citation: BMC Medical Informatics and Decision Making 2021 21:356
  15. Cardiotocography (CTG) interpretation plays a critical role in prenatal fetal monitoring. However, the interpretation of fetal status assessment using CTG is mainly confined to clinical research. To the best o...

    Authors: Liting Huang, Zhiying Jiang, Ruichu Cai, Li Li, Qinqun Chen, Jiaming Hong, Zhifeng Hao and Hang Wei
    Citation: BMC Medical Informatics and Decision Making 2021 21:355
  16. Acute care for critical illness requires very strict treatment timeliness. However, healthcare providers usually cannot accurately figure out the causes of low efficiency in acute care process due to the lack ...

    Authors: Jianfei Pang, Haifeng Xu, Jun Ren, Jun Yang, Mei Li, Dan Lu and Dongsheng Zhao
    Citation: BMC Medical Informatics and Decision Making 2021 21:354
  17. Information retrieval (IR) help clinicians answer questions posed to large collections of electronic medical records (EMRs), such as how best to identify a patient’s cancer stage. One of the more promising app...

    Authors: Cheng Ye, Bradley A. Malin and Daniel Fabbri
    Citation: BMC Medical Informatics and Decision Making 2021 21:353
  18. Semantic annotators and Natural Language Processing (NLP) methods for Named Entity Recognition and Linking (NER+L) require plenty of training and test data, especially in the biomedical domain. Despite the abunda...

    Authors: Fabio Giachelle, Ornella Irrera and Gianmaria Silvello
    Citation: BMC Medical Informatics and Decision Making 2021 21:352
  19. This study aimed to assess the performance improvement for machine learning-based hospital length of stay (LOS) predictions when clinical signs written in text are accounted for and compared to the traditional...

    Authors: Jan Chrusciel, François Girardon, Lucien Roquette, David Laplanche, Antoine Duclos and Stéphane Sanchez
    Citation: BMC Medical Informatics and Decision Making 2021 21:351
  20. Patients with severe Coronavirus disease 19 (COVID-19) typically require supplemental oxygen as an essential treatment. We developed a machine learning algorithm, based on deep Reinforcement Learning (RL), for...

    Authors: Hua Zheng, Jiahao Zhu, Wei Xie and Judy Zhong
    Citation: BMC Medical Informatics and Decision Making 2021 21:350
  21. In 2008, the Institut Català de la Salut (ICS, Catalan Health Institute) implemented a prescription decision support system in its electronic clinical workstation (ECW), which automatically generates online al...

    Authors: M. Àngels Pons-Mesquida, Míriam Oms-Arias, Eduard Diogène-Fadini and Albert Figueras
    Citation: BMC Medical Informatics and Decision Making 2021 21:349
  22. Due to the complexity and high heterogeneity of the acute exacerbation of chronic obstructive pulmonary disease (AECOPD), the guidelines (global initiative for chronic obstructive, GOLD) is unable to fully gui...

    Authors: Junfeng Peng, Mi Zhou, Kaiqiang Zou, Xiongyong Zhu, Jun Xu, Yi Teng, Feifei Zhang and Guoming Chen
    Citation: BMC Medical Informatics and Decision Making 2021 21:348
  23. Patients with hepatitis C virus (HCV) frequently remain at risk for cirrhosis after sustained virologic response (SVR). Existing cirrhosis predictive models for HCV do not account for dynamic antiviral treatme...

    Authors: Lauren A. Beste, Xuefei Zhang, Grace L. Su, Tony Van, George N. Ioannou, Brandon Oselio, Monica Tincopa, Boang Liu, Amit G. Singal, Ji Zhu and Akbar K. Waljee
    Citation: BMC Medical Informatics and Decision Making 2021 21:347
  24. Online doctor–patient consultation is a new option for orthopedic patients in China to obtain a diagnosis and treatment advice. This study explores the factors associated with online consultation to formulate ...

    Authors: Ping Lei, Jianjun Zheng, Yun Li, Zhongjiang Li, Fei Gao and Xuesong Li
    Citation: BMC Medical Informatics and Decision Making 2021 21:346
  25. Asthma is a chronic disease that exacerbates due to various risk factors, including the patient’s biosignals and environmental conditions. It is affecting on average 7% of the world population. Preventing an a...

    Authors: Eman T. Alharbi, Farrukh Nadeem and Asma Cherif
    Citation: BMC Medical Informatics and Decision Making 2021 21:345
  26. Alzheimer’s disease (AD) is a highly heterogeneous disease with diverse trajectories and outcomes observed in clinical populations. Understanding this heterogeneity can enable better treatment, prognosis and d...

    Authors: Nonie Alexander, Daniel C. Alexander, Frederik Barkhof and Spiros Denaxas
    Citation: BMC Medical Informatics and Decision Making 2021 21:343
  27. Although deep neural networks (DNNs) are showing state of the art performance in clinical gait analysis, they are considered to be black-box algorithms. In other words, there is a lack of direct understanding ...

    Authors: Benjamin Filtjens, Pieter Ginis, Alice Nieuwboer, Muhammad Raheel Afzal, Joke Spildooren, Bart Vanrumste and Peter Slaets
    Citation: BMC Medical Informatics and Decision Making 2021 21:341
  28. Recently, decision-making process has become increasingly complex. But there is limited information on Chinese patients’ views of shared decision making (SDM) in inflammatory bowel disease (IBD). This question...

    Authors: Dingting Xu, Hanyun Zhang and Yan Chen
    Citation: BMC Medical Informatics and Decision Making 2021 21:340
  29. Telehealth technology and related products can help to solve the problems associated with providing health care services and equal distribution of resources. However, in order to run a telehealth business succ...

    Authors: Farnia Velayati, Haleh Ayatollahi, Morteza Hemmat and Reza Dehghan
    Citation: BMC Medical Informatics and Decision Making 2021 21:339
  30. Neonatal jaundice may cause severe neurological damage if poorly evaluated and diagnosed when high bilirubin occurs. The study explored how to effectively integrate high-dimensional genetic features into predi...

    Authors: Haowen Deng, Youyou Zhou, Lin Wang and Cheng Zhang
    Citation: BMC Medical Informatics and Decision Making 2021 21:338
  31. Authors: Elisa Puigdomenech, Anne Martin, Alexandra Lang, Fulvio Adorni, Santiago Felipe Gomez, Brian McKinstry, Federica Prinelli, Laura Condon, Rajeeb Rashid, Maurizio Caon, Sarah Atkinson, Claudio L. Lafortuna, Valentina Ciociola, Janet Hanley, Lucy McCloughan, Conxa Castell…
    Citation: BMC Medical Informatics and Decision Making 2021 21:337

    The original article was published in BMC Medical Informatics and Decision Making 2019 19:278

  32. Much has been invested in big data and artificial intelligence-based solutions for healthcare. However, few applications have been implemented in clinical practice. Early economic evaluations can help to impro...

    Authors: Lytske Bakker, Jos Aarts, Carin Uyl-de Groot and Ken Redekop
    Citation: BMC Medical Informatics and Decision Making 2021 21:336
  33. Knowledge graphs (KGs), especially medical knowledge graphs, are often significantly incomplete, so it necessitating a demand for medical knowledge graph completion (MedKGC). MedKGC can find new facts based on...

    Authors: Yinyu Lan, Shizhu He, Kang Liu, Xiangrong Zeng, Shengping Liu and Jun Zhao
    Citation: BMC Medical Informatics and Decision Making 2021 21(Suppl 9):335

    This article is part of a Supplement: Volume 21 Supplement 9

  34. Sepsis, defined as life-threatening organ dysfunction caused by a dysregulated host response to infection, has become one of the major causes of death in Intensive Care Units (ICUs). The heterogeneity and comp...

    Authors: Ying Wu, Shuai Huang and Xiangyu Chang
    Citation: BMC Medical Informatics and Decision Making 2021 21:334
  35. Gene expression data play an important role in bioinformatics applications. Although there may be a large number of features in such data, they mainly tend to contain only a few samples. This can negatively im...

    Authors: Saeid Azadifar and Ali Ahmadi
    Citation: BMC Medical Informatics and Decision Making 2021 21:333
  36. An increase in the incidence of central venous catheter (CVC)-associated deep venous thrombosis (CADVT) has been reported in pediatric patients over the past decade. At the same time, current screening guideli...

    Authors: Haomin Li, Yang Lu, Xian Zeng, Cangcang Fu, Huilong Duan, Qiang Shu and Jihua Zhu
    Citation: BMC Medical Informatics and Decision Making 2021 21:332
  37. Buprenorphine is a widely used treatment option for patients with opioid use disorder (OUD). Premature discontinuation from this treatment has many negative health and societal consequences.

    Authors: Md Mahmudul Hasan, Gary J. Young, Jiesheng Shi, Prathamesh Mohite, Leonard D. Young, Scott G. Weiner and Md. Noor-E-Alam
    Citation: BMC Medical Informatics and Decision Making 2021 21:331
  38. Prostate cancer (PCa) is the leading male neoplasm in South Africa with an age-standardised incidence rate of 68.0 per 100,000 population in 2018. The Gleason score (GS) is the strongest predictive factor for ...

    Authors: Naseem Cassim, Michael Mapundu, Victor Olago, Turgay Celik, Jaya Anna George and Deborah Kim Glencross
    Citation: BMC Medical Informatics and Decision Making 2021 21:330
  39. To improve chronic disease outcomes, self-management is an effective strategy. An electronic personal health record (ePHR) is a promising tool with the potential to support chronic patient’s education, counsel...

    Authors: Esmaeel Toni, Habibollah Pirnejad, Khadijeh Makhdoomi, Azam Mivefroshan and Zahra Niazkhani
    Citation: BMC Medical Informatics and Decision Making 2021 21:329
  40. In surgical department, CPT code assignment has been a complicated manual human effort, that entails significant related knowledge and experience. While there are several studies using CPTs to make predictions...

    Authors: Tannaz Khaleghi, Alper Murat and Suzan Arslanturk
    Citation: BMC Medical Informatics and Decision Making 2021 21:328
  41. Due to the importance of segmentation of MRI images in identifying brain tumors, various methods including deep learning have been introduced for automatic brain tumor segmentation. On the other hand, using a ...

    Authors: Mohamadreza Hajiabadi, Behrouz Alizadeh Savareh, Hassan Emami and Azadeh Bashiri
    Citation: BMC Medical Informatics and Decision Making 2021 21:327
  42. Quality data from Health Management Information Systems (HMIS) are important for tracking the effectiveness of malaria control interventions. However, HMIS data in many resource-limited settings do not current...

    Authors: Azoukalné Moukénet, Monica Anna de Cola, Charlotte Ward, Honoré Beakgoubé, Kevin Baker, Laura Donovan, Jean Laoukolé and Sol Richardson
    Citation: BMC Medical Informatics and Decision Making 2021 21:326
  43. Patients with chronic obstructive pulmonary disease (COPD) experience deficits in exercise capacity and physical activity as their disease progresses. Pulmonary rehabilitation (PR) can enhance exercise capacit...

    Authors: Ning Deng, Leiyi Sheng, Wangshu Jiang, Yongfa Hao, Shuoshuo Wei, Bei Wang, Huilong Duan and Juan Chen
    Citation: BMC Medical Informatics and Decision Making 2021 21:325
  44. MyDiabetesPlan is a web-based, interactive patient decision aid that facilitates patient-centred, diabetes-specific, goal-setting and shared decision-making (SDM) with interprofessional health care teams.

    Authors: Catherine H. Yu, Farid Medleg, Dorothy Choi, Catherine M. Spagnuolo, Lakmini Pinnaduwage, Sharon E. Straus, Paul Cantarutti, Karen Chu, Paul Frydrych, Amy Hoang-Kim, Noah Ivers, David Kaplan, Fok-Han Leung, John Maxted, Jeremy Rezmovitz, Joanna Sale…
    Citation: BMC Medical Informatics and Decision Making 2021 21:323
  45. While random forests are one of the most successful machine learning methods, it is necessary to optimize their performance for use with datasets resulting from a two-phase sampling design with a small number ...

    Authors: Sunwoo Han, Brian D. Williamson and Youyi Fong
    Citation: BMC Medical Informatics and Decision Making 2021 21:322
  46. Cardiovascular diseases (CVDs) are always considered by healthcare specialists for different reasons, including extensive prevalence, increased costs, chronicity, and high risk of death. The control of CVDs is...

    Authors: Atiyeh Saboktakin, Mohammad Mehdi Sepehri and Roghaye Khasha
    Citation: BMC Medical Informatics and Decision Making 2021 21:321

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