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  1. Cost effectiveness research is emerging in the chronic kidney disease (CKD) research field. Especially, an individual-level state transition model (microsimulation) is widely used for these researches. Some re...

    Authors: Shusuke Hiragi, Hiroshi Tamura, Rei Goto and Tomohiro Kuroda
    Citation: BMC Medical Informatics and Decision Making 2018 18:94
  2. Technological support may be crucial in optimizing healthcare professional practice and improving patient outcomes. A focus on electronic health records has left other technological supports relatively neglect...

    Authors: C Keyworth, J Hart, C J Armitage and M P Tully
    Citation: BMC Medical Informatics and Decision Making 2018 18:93
  3. In recent years, inter-municipal cooperation in healthcare services has been an important measure implemented to meet future demographic changes in western countries. This entails an increased focus on communi...

    Authors: Elisabeth Holen-Rabbersvik, Elin Thygesen, Tom Roar Eikebrokk, Rune Werner Fensli and Åshild Slettebø
    Citation: BMC Medical Informatics and Decision Making 2018 18:92
  4. Trio studies, which involve the testing of samples from a proband and both parents, are often used by clinical laboratories to help with the classification of genetic variants, including copy number variants. ...

    Authors: Daniel Xia, Chen Zhang, Va Lip, Marian Harris and Yiping Shen
    Citation: BMC Medical Informatics and Decision Making 2018 18:91
  5. The health area is one of the most affected systems on the perspective of decision-making with multiobjectives, thus becoming prone to errors in the final solution, however, multicriteria decision analysis (MD...

    Authors: Talita D. C. Frazão, Deyse G. G. Camilo, Eric L. S. Cabral and Ricardo P. Souza
    Citation: BMC Medical Informatics and Decision Making 2018 18:90
  6. Molecular precision oncology is an emerging practice to improve cancer therapy by decreasing the risk of choosing treatments that lack efficacy or cause adverse events. However, the challenges of integrating m...

    Authors: Franziska Singer, Anja Irmisch, Nora C. Toussaint, Linda Grob, Jochen Singer, Thomas Thurnherr, Niko Beerenwinkel, Mitchell P. Levesque, Reinhard Dummer, Luca Quagliata, Sacha I. Rothschild, Andreas Wicki, Christian Beisel and Daniel J. Stekhoven
    Citation: BMC Medical Informatics and Decision Making 2018 18:89
  7. Online health information is unregulated and can be of highly variable quality. There is currently no singular quantitative tool that has undergone a validation process, can be used for a broad range of health...

    Authors: Julie M. Robillard, Jessica H. Jun, Jen-Ai Lai and Tanya L. Feng
    Citation: BMC Medical Informatics and Decision Making 2018 18:87
  8. Pharmacovigilance consists in monitoring and preventing the occurrence of adverse drug reactions (ADR). This activity requires the collection and analysis of data from the patient record or any other sources t...

    Authors: Thibault Ledieu, Guillaume Bouzillé, Frantz Thiessard, Karine Berquet, Pascal Van Hille, Eric Renault, Elisabeth Polard and Marc Cuggia
    Citation: BMC Medical Informatics and Decision Making 2018 18:86
  9. Increased digitalization of healthcare comes along with the cost of cybercrime proliferation. This results to patients’ and healthcare providers' skepticism to adopt Health Information Technologies (HIT). In E...

    Authors: Pantelis Natsiavas, Janne Rasmussen, Maja Voss-Knude, Κostas Votis, Luigi Coppolino, Paolo Campegiani, Isaac Cano, David Marí, Giuliana Faiella, Fabrizio Clemente, Marco Nalin, Evangelos Grivas, Oana Stan, Erol Gelenbe, Jos Dumortier, Jan Petersen…
    Citation: BMC Medical Informatics and Decision Making 2018 18:85
  10. The objective of this study was to investigate the impact of patient portal adoption on patients’ primary care utilization and appointment adherence.

    Authors: Xiang Zhong, Muxuan Liang, Reynerio Sanchez, Menggang Yu, Pamela R. Budd, Julie L. Sprague and Marvin A. Dewar
    Citation: BMC Medical Informatics and Decision Making 2018 18:84
  11. Recently, attention has shifted to improving the design of computerized alerts via the incorporation of human factors design principles. The Instrument for Evaluating Human Factors Principles in Medication-Rel...

    Authors: Melissa T Baysari, David Lowenstein, Wu Yi Zheng and Richard O Day
    Citation: BMC Medical Informatics and Decision Making 2018 18:83
  12. Current advances in information and communication technology have made accessing and obtaining health-related information easier than ever before. Today, many hospital websites use a patient-centric approach t...

    Authors: Dari Alhuwail, Zainab AlMeraj and Fatima Boujarwah
    Citation: BMC Medical Informatics and Decision Making 2018 18:82
  13. Patients suffering obstructive sleep apnea are mainly treated with continuous positive airway pressure (CPAP). Although it is a highly effective treatment, compliance with this therapy is problematic to achiev...

    Authors: Xavier Rafael-Palou, Cecilia Turino, Alexander Steblin, Manuel Sánchez-de-la-Torre, Ferran Barbé and Eloisa Vargiu
    Citation: BMC Medical Informatics and Decision Making 2018 18:81
  14. Worldwide, over 14% of individuals hospitalized for psychiatric reasons have readmissions to hospitals within 30 days after discharge. Predicting patients at risk and leveraging accelerated interventions can r...

    Authors: Khader Shameer, M. Mercedes Perez-Rodriguez, Roy Bachar, Li Li, Amy Johnson, Kipp W. Johnson, Benjamin S. Glicksberg, Milo R. Smith, Ben Readhead, Joseph Scarpa, Jebakumar Jebakaran, Patricia Kovatch, Sabina Lim, Wayne Goodman, David L. Reich, Andrew Kasarskis…
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 3):79

    This article is part of a Supplement: Volume 18 Supplement 3

  15. Clinical notes such as discharge summaries have a semi- or unstructured format. These documents contain information about diseases, treatments, drugs, etc. Extracting meaningful information from them becomes c...

    Authors: Ruth Reátegui and Sylvie Ratté
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 3):74

    This article is part of a Supplement: Volume 18 Supplement 3

  16. Numerous hospitals and organizations have recently endeavored to study the effects of real-time location systems. However, their experiences of system adoption or pilot testing via implementation were not shar...

    Authors: Sooyoung Yoo, Seok Kim, Eunhye Kim, Eunja Jung, Kee-Hyuck Lee and Hee Hwang
    Citation: BMC Medical Informatics and Decision Making 2018 18:80
  17. With connected medical devices fast becoming ubiquitous in healthcare monitoring there is a deluge of data coming from multiple body-attached sensors. Transforming this flood of data into effective and efficie...

    Authors: Rahul Krishnan Pathinarupothi, P. Durga and Ekanath Srihari Rangan
    Citation: BMC Medical Informatics and Decision Making 2018 18:78
  18. Treatment with effective antiretroviral therapy (ART) lowers morbidity and mortality among HIV positive individuals. Effective highly active antiretroviral therapy (HAART) should lead to undetectable viral loa...

    Authors: Kuteesa R. Bisaso, Susan A. Karungi, Agnes Kiragga, Jackson K. Mukonzo and Barbara Castelnuovo
    Citation: BMC Medical Informatics and Decision Making 2018 18:77
  19. Systematized Nomenclature of Medicine—Clinical Terms (SNOMED CT, hereafter abbreviated SCT) is a comprehensive medical terminology used for standardizing the storage, retrieval, and exchange of electronic heal...

    Authors: Shaker El-Sappagh, Francesco Franda, Farman Ali and Kyung-Sup Kwak
    Citation: BMC Medical Informatics and Decision Making 2018 18:76
  20. The openEHR approach can improve the interoperability of electronic health record (EHR) through two-level modeling. Developing archetypes for the complete EHR dataset is essential for implementing a large-scal...

    Authors: Lingtong Min, Qi Tian, Xudong Lu and Huilong Duan
    Citation: BMC Medical Informatics and Decision Making 2018 18:75
  21. After publication of this supplement article [1], it was brought to our attention that the Results section of the abstract contained a partial sentence.

    Authors: Zhiwei Chen, Zhe He, Xiuwen Liu and Jiang Bian
    Citation: BMC Medical Informatics and Decision Making 2018 18:73

    The original article was published in BMC Medical Informatics and Decision Making 2018 18:65

  22. Kidney stone (KS) disease has high, increasing prevalence in the United States and poses a massive economic burden. Diagnostics algorithms of KS only use a few variables with a limited sensitivity and specific...

    Authors: Zhaoyi Chen, Victoria Y. Bird, Rupam Ruchi, Mark S. Segal, Jiang Bian, Saeed R. Khan, Marie-Carmelle Elie and Mattia Prosperi
    Citation: BMC Medical Informatics and Decision Making 2018 18:72
  23. Traumatic injury is a serious global health burden, particularly in low- and middle-income countries where medical care often lacks resources and expertise. In these contexts, diagnostic telemedicine could pro...

    Authors: Iona Crumley, Lisa Blom, Lucie Laflamme and Helle Mölsted Alvesson
    Citation: BMC Medical Informatics and Decision Making 2018 18:71
  24. Portal use has been studied among outpatients, but its utility and impact on inpatients is unclear. This study describes portal adoption and use among hospitalized cancer patients and investigates associations...

    Authors: Duaa Aljabri, Adrian Dumitrascu, M. Caroline Burton, Launia White, Mahmud Khan, Sudha Xirasagar, Ronnie Horner and James Naessens
    Citation: BMC Medical Informatics and Decision Making 2018 18:70
  25. Usability flaws in medication alerting systems may have a negative impact on clinical use and patient safety. In order to prevent the release of alerting systems that contain such flaws, it is necessary to pro...

    Authors: Romaric Marcilly, Elske Ammenwerth, Erin Roehrer, Julie Niès and Marie-Catherine Beuscart-Zéphir
    Citation: BMC Medical Informatics and Decision Making 2018 18:69
  26. In the past few years, neural word embeddings have been widely used in text mining. However, the vector representations of word embeddings mostly act as a black box in downstream applications using them, there...

    Authors: Zhiwei Chen, Zhe He, Xiuwen Liu and Jiang Bian
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):65

    This article is part of a Supplement: Volume 18 Supplement 2

    The Correction to this article has been published in BMC Medical Informatics and Decision Making 2018 18:73

  27. Healthcare services, particularly in patient-provider interaction, often involve highly emotional situations, and it is important for physicians to understand and respond to their patients’ emotions to best en...

    Authors: Rebecca Lin, Muhammad “Tuan” Amith, Chen Liang, Rui Duan, Yong Chen and Cui Tao
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):64

    This article is part of a Supplement: Volume 18 Supplement 2

  28. Extracting relationships between chemicals and diseases from unstructured literature have attracted plenty of attention since the relationships are very useful for a large number of biomedical applications suc...

    Authors: Haodi Li, Ming Yang, Qingcai Chen, Buzhou Tang, Xiaolong Wang and Jun Yan
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):60

    This article is part of a Supplement: Volume 18 Supplement 2

  29. The emergence of the deep convolutional neural network (CNN) greatly improves the quality of computer-aided supporting systems. However, due to the challenges of generating reliable and timely results, clinica...

    Authors: Xinyuan Zhang, Shiqi Wang, Jie Liu and Cui Tao
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):59

    This article is part of a Supplement: Volume 18 Supplement 2

  30. Association Rule Mining (ARM) has been widely used by biomedical researchers to perform exploratory data analysis and uncover potential relationships among variables in biomedical datasets. However, when biome...

    Authors: Rashmie Abeysinghe and Licong Cui
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):58

    This article is part of a Supplement: Volume 18 Supplement 2

  31. Acute lymphoblastic leukemia is the most prevalent neoplasia among children. Despite the tremendous achievements of state-of-the-art treatment strategies, drug resistance is still a major cause of chemotherapy...

    Authors: Huiqin Chen, Dihua Zhang, Guoping Zhang, Xiaofeng Li, Ying Liang, Mohan Vamsi Kasukurthi, Shengyu Li, Glen M. Borchert and Jingshan Huang
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):57

    This article is part of a Supplement: Volume 18 Supplement 2

  32. In this editorial, we first summarize the 2nd International Workshop on Semantics-Powered Data Analytics (SEPDA 2017) held on November 13, 2017 in Kansas City, Missouri, U.S.A., and then briefly introduce 13 r...

    Authors: Zhe He, Cui Tao, Jiang Bian, Rui Zhang and Jingshan Huang
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):56

    This article is part of a Supplement: Volume 18 Supplement 2

  33. There is strong scientific evidence linking obesity and overweight to the risk of various cancers and to cancer survivorship. Nevertheless, the existing online information about the relationship between obesit...

    Authors: Juan Antonio Lossio-Ventura, William Hogan, François Modave, Yi Guo, Zhe He, Xi Yang, Hansi Zhang and Jiang Bian
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):55

    This article is part of a Supplement: Volume 18 Supplement 2

  34. Despite widespread use, the safety of dietary supplements is open to doubt due to the fact that they can interact with prescribed medications, leading to dangerous clinical outcomes. Electronic health records ...

    Authors: Yadan Fan and Rui Zhang
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):51

    This article is part of a Supplement: Volume 18 Supplement 2

  35. Most of the current work on clinical temporal relation identification follows the convention developed in the general domain, aiming to identify a comprehensive set of temporal relations from a document includ...

    Authors: Hee-Jin Lee, Yaoyun Zhang, Min Jiang, Jun Xu, Cui Tao and Hua Xu
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):49

    This article is part of a Supplement: Volume 18 Supplement 2

  36. Cardiac Resynchronization Therapy (CRT) is an established pacing therapy for heart failure patients. The New York Heart Association (NYHA) class is often used as a measure of a patient’s response to CRT. Ident...

    Authors: Rui Zhang, Sisi Ma, Liesa Shanahan, Jessica Munroe, Sarah Horn and Stuart Speedie
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):48

    This article is part of a Supplement: Volume 18 Supplement 2

  37. Suicide has been one of the leading causes of deaths in the United States. One major cause of suicide is psychiatric stressors. The detection of psychiatric stressors in an at risk population will facilitate t...

    Authors: Jingcheng Du, Yaoyun Zhang, Jianhong Luo, Yuxi Jia, Qiang Wei, Cui Tao and Hua Xu
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):43

    This article is part of a Supplement: Volume 18 Supplement 2

  38. Relationships between bio-entities (genes, proteins, diseases, etc.) constitute a significant part of our knowledge. Most of this information is documented as unstructured text in different forms, such as book...

    Authors: Kaixian Yu, Pei-Yau Lung, Tingting Zhao, Peixiang Zhao, Yan-Yuan Tseng and Jinfeng Zhang
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):42

    This article is part of a Supplement: Volume 18 Supplement 2

  39. Cancer is the second leading cause of death in the United States, exceeded only by heart disease. Extant cancer survival analyses have primarily focused on individual-level factors due to limited data availabi...

    Authors: Hansi Zhang, Yi Guo, Qian Li, Thomas J. George, Elizabeth Shenkman, François Modave and Jiang Bian
    Citation: BMC Medical Informatics and Decision Making 2018 18(Suppl 2):41

    This article is part of a Supplement: Volume 18 Supplement 2

  40. In low-resource settings, there are numerous socioeconomic challenges such as poverty, inadequate facilities, shortage of skilled health workers, illiteracy and cultural barriers that contribute to high matern...

    Authors: Stephen Mburu and Robert Oboko
    Citation: BMC Medical Informatics and Decision Making 2018 18:67
  41. Informatics for Integrating Biology and the Bedside (i2b2) is an open source clinical data analytics platform used at over 200 healthcare institutions for querying patient data. The i2b2 platform has several c...

    Authors: Kavishwar B. Wagholikar, Pralav Dessai, Javier Sanz, Michael E. Mendis, Douglas S. Bell and Shawn N. Murphy
    Citation: BMC Medical Informatics and Decision Making 2018 18:66
  42. Recent scientific achievements and technological advances have brought forward a massive display of new or updated medical devices, enabled with highly-developed embedded-control functions and interactivity. F...

    Authors: Ignacio Ghersi, Mario Mariño and Mónica Teresita Miralles
    Citation: BMC Medical Informatics and Decision Making 2018 18:63
  43. The use of knowledge models facilitates information retrieval, knowledge base development, and therefore supports new knowledge discovery that ultimately enables decision support applications. Most existing wo...

    Authors: Yiqing Zhao, Nooshin J. Fesharaki, Hongfang Liu and Jake Luo
    Citation: BMC Medical Informatics and Decision Making 2018 18:61
  44. Healthcare professionals provide care to patients and during that process, record large quantities of data in patient records. Data in an Electronic Health Record should ideally be recorded once and be reusabl...

    Authors: Erik Joukes, Ronald Cornet, Martine C. de Bruijne, Nicolette F. de Keizer and Ameen Abu-Hanna
    Citation: BMC Medical Informatics and Decision Making 2018 18:54
  45. Approaches to nurse staffing are commonly concerned with determining the minimum number of care hours according to the illness severity of patients. However, there is a gap in the literature considering multi-...

    Authors: Ana Respicio, Margarida Moz, Margarida Vaz Pato, Rute Somensi and Cecília Dias Flores
    Citation: BMC Medical Informatics and Decision Making 2018 18:53
  46. Despite the growing interest in developing markers for predicting treatment response and optimizing treatment decisions, an appropriate methodology to identify, combine and evaluate such markers has been slow ...

    Authors: Parvin Tajik, Mohammad Hadi Zafarmand, Aeilko H. Zwinderman, Ben W. Mol and Patrick M. Bossuyt
    Citation: BMC Medical Informatics and Decision Making 2018 18:52
  47. The performance of Computer Aided Diagnosis Systems for early melanoma detection relies mainly on quantitative evaluation of the geometric features corresponding to skin lesions. In these systems, diagnosis is...

    Authors: Agustin Sancen-Plaza, Raul Santiago-Montero, Humberto Sossa, Francisco J. Perez-Pinal, Juan J. Martinez-Nolasco and Jose A. Padilla-Medina
    Citation: BMC Medical Informatics and Decision Making 2018 18:50
  48. Text mining (TM) methods have been used extensively to extract relations and events from the literature. In addition, TM techniques have been used to extract various types or dimensions of interpretative informat...

    Authors: Matthew Shardlow, Riza Batista-Navarro, Paul Thompson, Raheel Nawaz, John McNaught and Sophia Ananiadou
    Citation: BMC Medical Informatics and Decision Making 2018 18:46

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