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Table 5 Examples of valid mappings identified by three approaches

From: Mapping of Alzheimer’s disease related data elements and the NIH Common Data Elements

Approach

Mapping resources

Data element 1

Data element 2

Similarity

Bag-of-words

NACC \(\rightarrow\) ADNI

Form: Neuropathology

CRF NAME: NACC Neuropathology Data Form

0.86

  

Short descriptor: Medial temporal lobe sclerosis present (including hippocampal sclerosis)

TEXT: Is medial temporal lobe sclerosis (including hippocampal sclerosis) present?

 

Bag-of-words

NACC \(\rightarrow\) NIH CDE

Form: Unified Parkinson’s Disease Rating Scale (UPDRS)

Name: Movement Disorder Society - Unified Parkinson’s Disease Rating Scale (MDS UPDRS) - finger tap right hand score

0.81

  

Short descriptor: Finger taps - right hand

Question Texts: FINGER TAPPING

 

Bag-of-words

ADNI \(\rightarrow\) NIH CDE

CRF NAME: Geriatric Depression Scale

Name: Geriatric Depression Scale (GDS) - feel helpless indicator

0.88

  

TEXT: 8. Do you often feel helpless?

Question Texts: Do you often feel helpless?

 

Word2Vec

NACC \(\rightarrow\) ADNI

Form: Imaging

CRF NAME: Longitudinal FreeSurfer

0.66

  

Short descriptor: Left fusiform mean cortical thickness (mm)

TEXT: Cortical Thickness Average of LeftFusiform

 

Word2Vec

NACC \(\rightarrow\) NIH CDE

Form: Behavioral Assessment - Geriatric Depression Scale

Name: Geriatric Depression Scale (GDS) - people better off indicator

0.78

  

Short descriptor: Do you think that most people are better off than you are?

Question Texts: Do you think that most people are better off than you are?

 

Word2Vec

ADNI \(\rightarrow\) NIH CDE

CRF NAME: ECG

Name: ECG PR interval

0.85

  

TEXT: PR Interval

Question Texts: PR interval

 

BioWordVec

NACC \(\rightarrow\) ADNI

Form: Functional Assessment NACC Functional Assessment Scale

CRF NAME: Functional Assessment Questionnaire

0.64

  

Short descriptor: In the past four weeks, did the subject have any difficulty or need help with: Remembering appointments, family occasions, holidays, medications

TEXT: 9. Remembering appointments, family occasions, holidays, medications.

 

BioWordVec

NACC \(\rightarrow\) NIH CDE

Form: Subject Health History

Name: Surgical history pacemaker indicator

0.63

  

Short descriptor: Pacemaker

Question Texts: Pacemaker

 

BioWordVec

ADNI \(\rightarrow\) NIH CDE

CRF NAME: Mini Mental State Exam (MMSE)

Name: Mini-Mental State Examination (MMSE) - total score

0.82

  

TEXT: MMSE TOTAL SCORE

Question Texts: MMSE total score