Table 1 Baseline characteristics of quartile groups of delta serum phosphate in sepsis patients
Variables | Delta serum phosphate level during the first 3 days of ICU admission (mg/dL) | P value | |||
|---|---|---|---|---|---|
|  | 0−1.3 | 1.4−2.0 | 2.1–3.1 | ≥ 3.2 | |
N | 293 | 355 | 370 | 357 | Â |
Female, n (%) | 131 (44.71) | 171 (48.17) | 149 (40.27) | 127 (35.57) | 0.005 |
Age, M(P25,P75) | 59 (49,69) | 59 (50,70) | 62 (54,69) | 61 (51,68) | 0.030 |
Infection site, n (%) | Â | Â | Â | Â | 0.005 |
-Respiratory system | 110 (37.54) | 118 (33.24) | 112 (30.27) | 97 (27.17) | Â |
-Urinary system | 7 (2.39) | 10 (2.82) | 8 (2.16) | 7 (1.96) | Â |
-Soft tissue infection | 15 (5.12) | 16 (4.51) | 17 (4.60) | 9 (2.52) | Â |
-Digestive system | 46 (15.70) | 64 (18.03) | 73 (19.73) | 55 (15.41) | Â |
-Hematologic | 28 (9.56) | 27 (7.60) | 14 (3.78) | 28 (7.84) | Â |
-other | 87 (29.69) | 120 (33.80) | 146 (39.46) | 161 (45.10) | Â |
Comorbidity, n (%) | Â | Â | Â | Â | Â |
-AKI | 91 (31.06) | 126 (35.49) | 136 (36.76) | 185 (51.82) | < 0.001 |
-Intestine disease | 35 (11.95) | 52 (14.65) | 73 (19.73) | 40 (11.20) | 0.005 |
-Septic shock | 212 (72.35) | 261 (73.52) | 274 (74.05) | 286 (80.11) | 0.083 |
Hospital stay time /day, M(P25,P75) | 15.81 (9.84,26.77) | 16.01 (10.90,28.86) | 17.88 (11.24,27.21) | 17.25 (9.63,28.64) | 0.557 |
ICU stay time /day, M(P25,P75) | 8.23 (5.70,14.84) | 8.09 (5.29,13.79) | 8.96 (5.84,15.55) | 9.64 (5.93,16.92) | 0.128 |
Invasive mechanical ventilation time /h, M(P25,P75) | 121.35 (50.00,218.00) | 89.10 (33.00,182.90) | 97.80 (52.00,208.13) | 126.00 (67.50,233.50) | 0.035 |
Noninvasive mechanical ventilation time /h, M(P25,P75) | 16.75 (2.16,44.50) | 31.08 (4.50,68.00) | 26.33 (5.78,59.36) | 17.80 (0,50.83) | 0.161 |
GCS score, M(P25,P75) | 7.67 (5.92,10.08) | 8.39 (6.50,10.71) | 8.46 (6.69,10.40) | 10.13 (8.04,12.46) | 0.667 |
SOFA score, \( \bar x \pm s \) | 6.80 ± 2.73 | 7.29 ± 2.85 | 7.79 ± 2.87 | 9.60 ± 3.29 | < 0.001 |
APACHEII score, M(P25,P75) | 26 (23,29) | 27 (23,30) | 29 (23,32) | 30 (27,34) | < 0.001 |
[Pi]first (mg/dl), M(P25,P75) | 3.20 (2.50,4.10) | 3.60 (3.00,4.70) | 4.20 (3.40,5.10) | 5.70 (4.20,7.15) | < 0.001 |
[Pi]min (mg/dl), M(P25,P75) | 2.60 (2.10,3.50) | 2.60 (2.00,3.60) | 2.60 (1.95,3.45) | 2.60 (1.80,3.60) | 0.265 |
[Pi]max (mg/dl), M(P25,P75) | 3.50 (3.00,4.40) | 4.40 (3.70,5.30) | 5.20 (4.30,6.20) | 7.10 (6.00,8.35) | < 0.001 |
[Pi]mean (mg/dl), M(P25,P75) | 3.03 (2.58,3.84) | 3.41 (2.71,4.30) | 3.74 (3.07,4.68) | 4.54 (3.44,5.86) | < 0.001 |
Albumin (g/dl), M(P25,P75) | 2.68 (2.20,3.00) | 2.60 (2.30,2.90) | 2.70 (2.35,3.10) | 2.60 (2.30,3.13) | 0.109 |
Creatinine (mg/dl), M(P25,P75) | 1.00 (0.67,2.03) | 1.37 (0.93,2.17) | 1.58 (1.04,2.46) | 2.52 (1.70,3.74) | < 0.001 |
WBC (*109/), M(P25,P75) | 14.35 (9.83,20.65) | 13.33 (9.00,21.00) | 16.25 (10.95,21.04) | 16.07 (9.80,21.93) | 0.546 |
pH, \( \bar x \pm s \) | 7.36 ± 0.07 | 7.35 ± 0.07 | 7.32 ± 0.07 | 7.29 ± 0.08 | < 0.001 |
Enteral nutrition, n(%) | 102 (34.81) | 100 (28.17) | 115 (31.08) | 98 (27.45) | 0.167 |
Parenteral nutrition, n(%) | 33 (11.26) | 43 (12.11) | 43 (11.62) | 42 (11.76) | 0.990 |
Types of vasoactive agents, M(P25,P75) | 1 (1,2) | 1 (1,2) | 2 (1,2) | 2 (1,2) | < 0.001 |
In-hospital mortality, n(%) | 70 (23.89) | 100 (28.17) | 104 (28.11) | 129 (36.13) | 0.005 |
28-day mortality, n(%) | 89 (31.59) | 122 (34.37) | 119 (32.16) | 150 (42.02) | 0.008 |