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Table 1 Algorithm description

From: Natural language processing to identify lupus nephritis phenotype in electronic health records

Algorithm name

Classification model

Description

Baseline algorithm

Rule-based

A patient is confirmed to have lupus nephritis if he/she has proteinuria > 0.5 mg in laboratory test or has ICD 9/10 diagnosis code for lupus nephritis.

Full MetaMap model (binary)

L2-regularized logistic regression

Features are the non-negative mention of MetaMap CUIs. We treated CUIs as binary variables and fitted L2-regularized logistic regression to predict lupus nephritis.

Full MetaMap model (count)

L2-regularized logistic regression

The same as the full MetaMap model (binary) except that MetaMap CUIs are treated as numeric variables representing the count of instances each concept is mentioned in the clinical text.

MetaMap mixed model

L2-regularized logistic regression

There are 13 features in this model including 7 CUI features, 5 RegEx concepts, and 1 feature from structured data.