Table 1 Baseline Characteristics of patients

Sex (%)

Male

136 (55.5)

40 (58.8)

0.727

54 (56.8)

15 (51.7)

0.786

Female

109 (44.5)

28 (41.2)

41 (43.2)

14 (48.3)

Age(mean (median [IQR])

52.00 [40.00, 65.00]

54.00 [42.00, 72.00]

0.242

52.00 [38.00, 65.50]

58.00 [44.00, 71.00]

0.093

Etiology (%)

Biliary

110 (44.9)

25 (36.8)

0.317

37 (38.9)

13 (44.8)

0.443

Hyperlipidemia

47 (19.2)

20 (29.4)

14 (14.7)

6 (20.7)

Alcoholic

13 (5.3)

3 (4.4)

6 (6.3)

0 (0.0)

Others

75 (30.6)

20 (29.4)

38 (40.0)

10 (34.5)

Smoke (%)

No

221 (90.2)

57 (83.8)

0.208

87 (91.6)

24 (82.8)

0.255

Yes

24 (9.8)

11 (16.2)

7 (7.4)

5 (17.2)

Hypertension (%)

No

170 (69.4)

33 (48.5)

0.002

70 (73.7)

18 (62.1)

0.331

Yes

75 (30.6)

35 (51.5)

25 (26.3)

11 (37.9)

Diabetes (%)

No

225 (91.8)

62 (91.2)

1

85 (89.5)

27 (93.1)

0.826

Yes

20 (8.2)

6 (8.8)

10 (10.5)

2 (6.9)

SBP (median [IQR])

130.00 [119.00, 142.00]

135.50 [120.00, 146.00]

0.073

133.00 [120.00, 143.50]

130.00 [126.00, 151.00]

0.392

DBP (median [IQR])

80.00 [71.00, 87.00]

79.50 [70.00, 88.50]

0.918

80.00 [72.50, 87.00]

80.00 [78.00, 85.00]

0.638

MAP (median [IQR])

96.67 [88.33, 105.00]

96.67 [90.00, 109.50]

0.586

96.33 [89.50, 105.00]

96.67 [94.67, 104.67]

0.313

PLT (*10⁹/L) (median [IQR])

186.00 [146.00, 229.00]

181.50 [132.00, 239.00]

0.684

179.00 [152.50, 225.00]

155.00 [132.00, 214.00]

0.175

WBC (*10⁹/L) (median [IQR])

11.10 [8.80, 14.10]

13.00 [9.60, 16.22]

0.038

11.60 [8.70, 15.30]

10.00 [8.50, 15.30]

0.662

N (*10⁹/L) (median [IQR])

9.10 [6.40, 11.80]

10.55 [6.77, 13.95]

0.055

9.60 [6.25, 12.15]

8.70 [6.10, 13.60]

0.894

L (*10⁹/L) (median [IQR])

1.30 [0.90, 1.80]

1.30 [0.80, 1.95]

0.946

1.20 [0.90, 1.90]

1.40 [0.70, 1.70]

0.456

HCT (L/L) (median [IQR])

0.43 [0.39, 0.46]

0.41 [0.36, 0.47]

0.256

0.42 [0.39, 0.46]

0.41 [0.39, 0.44]

0.064

RDW (%) (median [IQR])

12.80 [12.30, 13.40]

12.80 [12.50, 13.30]

0.971

12.70 [12.35, 13.30]

13.00 [12.60, 13.70]

0.136

Lr (%) (median [IQR])

12.10 [7.30, 17.90]

9.80 [7.07, 15.38]

0.166

11.30 [7.30, 19.85]

11.40 [5.00, 17.50]

0.41

Cr (µmol/L) (median [IQR])

63.00 [53.00, 74.00]

72.50 [61.00, 91.00]

< 0.001

63.00 [54.00, 74.00]

84.00 [65.00, 96.00]

< 0.001

TB (µmol/L) (median [IQR])

23.20 [15.70, 37.20]

22.80 [14.85, 35.25]

0.493

20.90 [14.00, 30.10]

16.70 [13.00, 26.40]

0.405

DB (µmol/L) (median [IQR])

8.20 [4.80, 16.40]

6.30 [4.47, 18.33]

0.561

7.20 [4.00, 13.05]

6.30 [4.10, 9.50]

0.906

Urea (mmol/L) (median [IQR])

4.60 [3.80, 5.70]

5.35 [4.40, 6.78]

0.001

4.50 [3.60, 6.05]

5.60 [4.00, 7.10]

0.01

LDH (U/L) (median [IQR])

227.00 [182.00, 319.00]

258.00 [193.75, 418.75]

0.051

230.00 [182.50, 312.00]

302.00 [213.00, 462.00]

0.023

Ca²⁺(mmol/L) (median [IQR])

2.25 [2.13, 2.37]

2.18 [2.04, 2.30]

0.028

2.24 [2.14, 2.35]

2.28 [2.19, 2.37]

0.122

TG (mmol/L) (median [IQR])

1.48 [0.89, 3.58]

1.72 [1.00, 9.36]

0.105

1.33 [0.89, 2.96]

1.78 [0.94, 3.87]

0.242

GLU (mmol/L) (median [IQR])

7.54 [6.20, 9.65]

7.91 [6.32, 11.01]

0.326

7.20 [6.43, 10.13]

7.63 [6.94, 8.94]

0.635

ALT (U/L) (median [IQR])

56.00 [22.00, 192.00]

36.50 [20.00, 96.25]

0.122

39.00 [21.00, 179.50]

45.00 [25.00, 122.00]

0.63

AST (U/L) (median [IQR])

49.00 [22.00, 169.00]

34.50 [23.00, 91.50]

0.435

31.00 [18.00, 102.50]

42.00 [27.00, 101.00]

0.154

GGT (U/L) (median [IQR])

126.00 [40.00, 345.00]

134.50 [34.50, 300.25]

0.685

80.00 [33.00, 245.00]

71.00 [46.00, 233.00]

0.908

ALP (U/L) (median [IQR])

107.00 [80.00, 163.00]

101.00 [81.00, 146.25]

0.818

107.00 [83.50, 145.00]

102.00 [79.00, 161.00]

0.934

ALB (g/L) (median [IQR])

39.00 [35.50, 42.40]

36.30 [32.88, 40.02]

< 0.001

38.90 [35.75, 40.90]

37.60 [32.20, 40.20]

0.153

Na⁺(mmol/L) (median [IQR])

139.30 [137.30, 141.60]

138.10 [134.88, 140.85]

0.011

140.10 [136.15, 142.40]

138.40 [136.00, 140.20]

0.083

AMY(U/L) (median [IQR])

460.00 [145.00, 1415.00]

330.00 [97.25, 1162.50]

0.22

496.00 [200.50, 1416.00]

278.00 [104.00, 753.00]

0.268

K⁺(U/L) (median [IQR])

3.92 [3.63, 4.17]

3.78 [3.49, 4.10]

0.103

3.92 [3.71, 4.18]

4.01 [3.79, 4.49]

0.082

PT (s) (median [IQR])

13.40 [12.40, 14.60]

12.95 [11.97, 14.20]

0.132

13.40 [12.30, 14.55]

13.20 [12.30, 14.70]

0.839

INR (median [IQR])

1.09 [1.00, 1.19]

1.04 [0.95, 1.14]

0.018

1.11 [1.01, 1.20]

1.05 [0.98, 1.23]

0.277

APTT (s) (median [IQR])

32.60 [29.40, 37.30]

31.75 [28.70, 36.42]

0.34

31.90 [28.80, 34.95]

33.30 [29.40, 35.70]

0.446

CRP (mg/L) (median [IQR])

10.50 [2.30, 52.60]

12.35 [4.18, 96.70]

0.057

9.10 [2.00, 68.15]

6.00 [2.10, 54.00]

0.495