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Table 1 Baseline characteristics of participants

From: The automatic detection of diabetic kidney disease from retinal vascular parameters combined with clinical variables using artificial intelligence in type-2 diabetes patients

 

non-DKD

(n = 366)

DKD

(n = 149)

Total

(n = 515)

P value

Risk factors

 Age (year)

52.8 ± 0.51

57.3 ± 0.94

54.1 ± 0.46

 < 0.05

 Gender (Male %)

65.3

63.1

63.9

0.810

 Duration (month)

71.7 ± 4.0

105.9 ± 7.0

81.6 ± 3.5

 < 0.05

 Hypertention

38.9

67.8

46.8

 < 0.05

 History (%)

13.9

26.2

17.3

 < 0.05

 Smoking (%)

42.5

45.0

42.7

0.799

 BMI (kg/m2)

25.5 ± 0.19

26.0 ± 0.31

25.6 ± 0.16

0.109

 HbA1c (%)

8.9 ± 0.13

9.7 ± 0.19

9.1 ± 0.12

 < 0.05

 UACR (mg/g)

11.8 ± 0.56

176.9 ± 20.91

59.6 ± 6.90

 < 0.05

 eGFR(ml/min/1.73m2)

115.2 ± 1.44

98.1 ± 3.53

110.3 ± 1.48

 < 0.05

Vascular parameters

 NVArea /104 (μm2)

163.24 ± 0.39

172.77 ± 0.97

166.00 ± 0.44

 < 0.05

 Tortuosity

0.481 ± 0.0005

0.483 ± 0.0009

0.481 ± 0.0108

0.0145

 FD

1.4229 ± 0.0001

1.4105 ± 0.0218

1.4193 ± 0.0001

 < 0.05

VW(All) (μm)

 Central

57.10 ± 0.25

57.64 ± 0.41

57.24 ± 0.20

0.2651

 Middle

52.37 ± 0.24

53.57 ± 0.39

52.72 ± 0.20

0.0076

 Peripheral

42.97 ± 0.18

45.13 ± 0.32

43.60 ± 0.16

 < 0.05

VW(Vein) (μm)

 Central

57.18 ± 0.25

57.64 ± 0.41

57.32 ± 0.20

0.334

 Middle

52.34 ± 0.23

53.56 ± 0.40

52.68 ± 0.20

0.0066

 Peripheral

42.96 ± 0.18

45.15 ± 0.31

43.60 ± 0.16

 < 0.05

VW(Artery) (μm)

 Central

42.97 ± 0.18

45.13 ± 0.32

48.24 ± 0.24

 < 0.05

 Middle

42.97 ± 0.18

45.13 ± 0.32

47.12 ± 0.20

 < 0.05

 Peripheral

42.83 ± 0.19

44.40 ± 0.33

43.28 ± 0.16

 < 0.05

  1. Abbreviations: DKD Indicates diabetic kidney disease, BMI Body mass index, HbA1c Glycosylated hemoglobin, UACR Urinary albuminuria creatinine ratio, eGFR Estimated glumerular filtration rate, NVArea Non-vascular area, Tortuosity total Vessel tortuosity, FD total Fractal dimension, VW Vessel width, History History of cardiovascular and cerebrovascular disease (myocardial infarction, angina, heart failure or stroke)