Table 1 Characteristics at baseline between the non-SAD and SAD groups
From: A nomogram for predicting sepsis-associated delirium: a retrospective study in MIMIC III
|  | Total (n = 642) | Non-SAD (n = 414) | SAD (n = 228) | P-value | |
|---|---|---|---|---|---|
Age, years | 68.72 [56.87, 79.14] | 69.13 [57.12, 79.54] | 66.56 [56.77, 77.70] | 0.483 | |
Gender (n, %) | Male | 326 (50.8) | 200 (48.3) | 126 (55.3) | 0.109 |
| Â | Female | 316 (49.2) | 214 (51.7) | 102 (44.7) | |
Ethnicity (n, %) | White | 429 (66.8) | 287 (69.3) | 142 (62.3) | 0.001 |
| Â | Asian | 18 (2.8) | 14 (3.4) | 4 (1.8) | Â |
| Â | Black | 83 (12.9) | 53 (12.8) | 30 (13.2) | |
| Â | Hispanic or Latino | 26 (4.0) | 21 (5.1) | 5 (2.2) | Â |
| Â | Others | 86 (13.4) | 39 (9.4) | 47 (20.6) | |
Admission type (n, %) | Elective | 42 (6.5) | 27 (6.5) | 15 (6.6) | 0.993 |
| Â | Emergency | 594 (92.5) | 383 (92.5) | 211 (92.5) | |
| Â | Urgent | 6 (0.9) | 4 (1.0) | 2 (0.9) | Â |
severe score | SAPSII | 28.00 [20.00, 38.00] | 26.00 [19.00, 34.00] | 32.00 [24.00, 42.00] | < 0.001 |
|  | SOFA | 5.00 [4.00, 8.00] | 5.00 [3.00, 7.00] | 7.00 [4.00, 10.00] | < 0.001 |
| Â | GCS | 15.00 [14.00, 15.00] | 15.00 [14.00, 15.00] | 14.00 [13.00, 15.00] | 0.004 |
Hospital length of stay, days | 10.32 [6.48, 17.89] | 8.29 [5.81, 13.88] | 15.22 [9.71, 22.14] | < 0.001 | |
ICU length of stay, days | 3.65 [2.00, 7.56] | 2.75 [1.71, 4.62] | 7.61 [3.80, 13.82] | < 0.001 | |
Mechanical ventilation (n, %) | 322 (50.2) | 158 (38.2) | 164 (71.9) | < 0.001 | |
28-day mortality in hospital(n, %) | 124 (19.3) | 60 (14.5) | 64 (28.1) | < 0.001 | |
Vital signs | Mean heartrate (min-1) | 88.96 [76.46, 101.25] | 88.77 [76.11, 100.31] | 90.19 [77.09, 102.98] | 0.174 |
| Â | Mean arterial pressure (mmHg) | 71.89 [66.18, 79.35] | 71.61 [65.67, 78.66] | 73.38 [67.31, 80.25] | 0.109 |
| Â | Mean respiratory rate (min-1) | 19.70 [16.97, 22.72] | 19.45 [16.78, 22.54] | 20.14 [17.22, 22.98] | 0.096 |
|  | Mean temperature (°C) | 36.83 [36.50, 37.21] | 36.83 [36.50, 37.20] | 36.85 [36.50, 37.30] | 0.359 |
| Â | Mean SpO2 (%) | 97.28 [95.93, 98.54] | 97.16 [95.77, 98.48] | 97.56 [96.30, 98.67] | 0.079 |
Laboratory tests | Blood glucose (mg/dl) | 135.88 [111.21, 166.50] | 134.88 [111.10, 164.14] | 139.00 [112.24, 174.52] | 0.209 |
| Â | WBC (K/uL) | 11.80 [7.40, 16.60] | 11.30 [7.20, 15.88] | 12.70 [8.05, 17.83] | 0.017 |
| Â | RBC (K/uL) | 3.54 [3.04, 4.11] | 3.54 [3.01, 4.07] | 3.53 [3.08, 4.18] | 0.402 |
| Â | Hemoglobin (g/dL) | 10.60 [9.10, 12.50] | 10.55 [9.10, 12.40] | 10.75 [9.20, 12.60] | 0.507 |
| Â | Platelet (K/uL) | 211.00 [142.00, 289.75] | 212.00 [144.00, 288.25] | 209.50 [139.50, 293.25] | 0.774 |
| Â | HCT (%) | 32.65 [28.22, 37.60] | 32.40 [27.72, 37.30] | 33.45 [28.58, 38.52] | 0.076 |
| Â | Creatinine (mg/dl) | 1.30 [0.90, 2.20] | 1.30 [0.90, 2.00] | 1.40 [0.90, 2.40] | 0.218 |
|  | Phosphate (mg/dl) | 3.60 [2.70, 4.60] | 3.50 [2.70, 4.40] | 4.00 [3.00, 5.00] | < 0.001 |
| Â | BUN (mg/dl) | 27.00 [17.00, 46.00] | 27.00 [17.00, 45.00] | 27.00 [17.75, 49.25] | 0.413 |
| Â | Sodium (K/uL) | 137.00 [134.00, 140.00] | 137.00 [133.00, 140.00] | 137.00 [134.00, 140.00] | 0.146 |
| Â | Potassium (K/uL) | 4.20 [3.80, 4.80] | 4.20 [3.70, 4.70] | 4.40 [3.90, 4.82] | 0.016 |
| Â | Lactate (mmol/L) | 1.80 [1.30, 2.80] | 1.70 [1.22, 2.50] | 1.90 [1.30, 3.20] | 0.015 |
Comorbodity (n, %) | Cardiovascular diseases | 410 (63.9) | 252 (60.9) | 158 (69.3) | 0.041 |
| Â | Peripheral vascular | 80 (12.5) | 47 (11.4) | 33 (14.5) | 0.307 |
| Â | Hypertension | 419 (65.3) | 264 (63.8) | 155 (68.0) | 0.324 |
|  | Other neurological diseases | 80 (12.5) | 36 (8.7) | 44 (19.3) | < 0.001 |
| Â | Chronic pulmonary | 220 (34.3) | 133 (32.1) | 87 (38.2) | 0.146 |
| Â | Renel failure | 199 (31.0) | 129 (31.2) | 70 (30.7) | 0.975 |
| Â | Liver failure | 98 (15.3) | 58 (14.0) | 40 (17.5) | 0.282 |
| Â | DM | 242 (37.7) | 164 (39.6) | 78 (34.2) | 0.205 |