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Table 4 Pharmacistsā€™ willingness to accept AI recommendations

From: Discrepancy between perceptions and acceptance of clinical decision support Systems: implementation of artificial intelligence for vancomycin dosing

Perception

Theme

Example Quote

Agree

Similar dose scheme

ā€œI could agree with the model recommendation. There really there so close, I don't, although the interval for the model was slightly higher, which, which, you know, sometimes that might be the case.ā€

ā€œif it more closely resembled my dosing, if it was just a little bit off, I would be more likely to use it.ā€

Concessions to AI

ā€œIf a model told me that dose would be acceptable, I probably would kind of split the difference.ā€

AI is better

ā€œI would change the dose because I was on the higher side and would want to minimize renal injury. Itā€™s slightly lower than my dose. I prefer the AIā€™s recommendation and would have chosen thatā€

Disagree

Don't trust the AI

ā€œOh, I think I would follow my dose. I don't think that trained model recommendation because I've given his age and his body weight and is severity illness, I would want to be a little more aggressive.ā€

Lack of dynamic evaluation

ā€œI do not want to change. I always start patients aggressively and then monitor closely.Ā So even if I start q8h, and then I find that creatinine is worse, or hemodynamics look poor, and they had decreased urine output, I would make a decision to check a level sooner.Ā However, in the ICU, you know, initial creatinine is just a starting point; we have to follow up and double-check and triple-check.ā€

Lack of in-depth analysis

ā€œI wouldn't want to change my dose at this point until we got cultures back for the simple fact if we don't know what and sensitivities are going to be. She is a very complicated clinical course, and I do not want to make it worse by underdosing in the beginning.ā€

ā€œThis seems to be painful to me, and I would want to have the higher dose. because it's an infection of the knee joint, which means you need a high target range to get a high enough concentration of the drug at the actual site of the infection.ā€

Not all data can be consolidated

ā€œI wouldn't change it. I will keep it the same. You really need to correlate the numbers you see on the labs with the patient's clinical picture.ā€

RiskĀ index

ā€œSo as a result, I think I won't change my dose unless you told me that I had a 95% chance of overdosing. I'd want to know what that's based on.ā€

Vial sizes

ā€œSometimes we think about vial sizes also, so we don't waste medication and ease of dosing.ā€

  1. AI Artificial Intelligence, ICU Intensive care unit, q8h Every 8Ā h