Table 3 Distribution of survival outcomes in populations with different features
From: Prognostic models for breast cancer: based on logistics regression and Hybrid Bayesian Network
Characteristics | Outcome | p value | |
|---|---|---|---|
Survival N = 29,230(%) | Dead N = 29,230(%) | ||
Age (year) | 61.0 [51.0;70.0] | 60.0 [51.0;66.0] | <0.001*** |
Tumor Size (mm) | 17.0 [10.0;28.0] | 23.0 [15.0;36.0] | 0.000*** |
Radiation | Â | Â | <0.001*** |
Beam radiation | 18,072 (61.8%) | 14,449 (49.4%) | Â |
Radioactive implants | 432 (1.48%) | 451 (1.54%) | Â |
Others | 10,726 (36.7%) | 14,330 (49.0%) | Â |
Surg | Â | Â | 0.000*** |
No | 2119 (7.25%) | 9845 (33.7%) | Â |
Yes | 27,111 (92.8%) | 19,385 (66.3%) | Â |
Chemotherapy | Â | Â | 0.000*** |
No | 18,207 (62.3%) | 13,326 (45.6%) | Â |
Yes | 11,023 (37.7%) | 15,904 (54.4%) | Â |
Mets | Â | Â | 0.000*** |
No distant metastasis | 27,891 (95.4%) | 18,461 (63.2%) | Â |
No evidence of distant mets | 43 (0.15%) | 47 (0.16%) | Â |
Distant lymph node(s) | 129 (0.44%) | 759 (2.60%) | Â |
Others | 1167 (3.99%) | 9963 (34.1%) | Â |
Subtype | Â | Â | 0.000*** |
HR-/HER2- | 2856 (9.77%) | 5186 (17.7%) | Â |
HR-/HER2+ | 1119 (3.83%) | 1575 (5.39%) | Â |
HR+/HER2- | 22,302 (76.3%) | 17,406 (59.5%) | Â |
HR+/HER2+ | 2953 (10.1%) | 5063 (17.3%) | Â |
Stage | Â | Â | 0.000*** |
1Â A | 16,899 (57.8%) | 10,961 (37.5%) | Â |
1B | 4841 (16.6%) | 3438 (11.8%) | Â |
2Â A | 2849 (9.75%) | 1962 (6.71%) | Â |
2B | 1446 (4.95%) | 1012 (3.46%) | Â |
3Â A | 792 (2.71%) | 448 (1.53%) | Â |
3B | 727 (2.49%) | 436 (1.49%) | Â |
3Â C | 380 (1.30%) | 291 (1.00%) | Â |
4 | 1296 (4.43%) | 10,682 (36.5%) | Â |
ER | Â | Â | <0.001*** |
Negative | 4283 (14.7%) | 7759 (26.5%) | Â |
Positive | 24,947 (85.3%) | 21,471 (73.5%) | Â |
PR | Â | Â | <0.001*** |
Negative | 7288 (24.9%) | 10,934 (37.4%) | Â |
Positive | 21,942 (75.1%) | 18,296 (62.6%) | Â |
Histologic | Â | Â | 0.000*** |
8500 | 24,910 (85.2%) | 20,488 (70.1%) | Â |
8507 | 97 (0.33%) | 370 (1.27%) | Â |
8520 or 8521 | 2992 (10.2%) | 4080 (14.0%) | Â |
8522 | 1041 (3.56%) | 2777 (9.50%) | Â |
8523 or 8524 | 135 (0.46%) | 219 (0.75%) | Â |
8530 | 31 (0.11%) | 1238 (4.24%) | Â |
Others | 24 (0.08%) | 58 (0.20%) | Â |
Grade | Â | Â | 0.000*** |
1 | 6392 (21.9%) | 4349 (14.9%) | Â |
2 | 10,701 (36.6%) | 7738 (26.5%) | Â |
3 | 5282 (18.1%) | 4281 (14.6%) | Â |
4 | 6855 (23.5%) | 12,862 (44.0%) | Â |
Site | Â | Â | 0.000*** |
C501 | 1309 (4.48%) | 1727 (5.91%) | Â |
C502 | 3985 (13.6%) | 2916 (9.98%) | Â |
C503 | 1629 (5.57%) | 1226 (4.19%) | Â |
C504 | 10,291 (35.2%) | 10,142 (34.7%) | Â |
C505 | 2398 (8.20%) | 1420 (4.86%) | Â |
C508 | 6938 (23.7%) | 6190 (21.2%) | Â |
C509 | 2680 (9.17%) | 5609 (19.2%) | Â |
Race | Â | Â | 0.000*** |
White | 22,030 (75.4%) | 17,832 (61.0%) | Â |
Black | 2719 (9.30%) | 6324 (21.6%) | Â |
Others | 4481 (15.3%) | 5074 (17.4%) | Â |
Marital | Â | Â | 0.000*** |
Married | 18,114 (62.0%) | 14,102 (48.2%) | Â |
Divorced | 3115 (10.7%) | 3195 (10.9%) | Â |
Separated | 209 (0.72%) | 664 (2.27%) | Â |
Single | 4428 (15.1%) | 8093 (27.7%) | Â |
Unmarried or Domestic Partner | 302 (1.03%) | 340 (1.16%) | Â |
Widowed | 3062 (10.5%) | 2836 (9.70%) | Â |
Laterality | Â | Â | <0.001*** |
Left - origin of primary | 14,886 (50.9%) | 13,596 (46.5%) | Â |
Right - origin of primary | 14,344 (49.1%) | 15,634 (53.5%) | Â |
Node | Â | Â | \(<\)0.001*** |
0 | 6995 (23.9%) | 5838 (20.0%) | Â |
1 | 13,616 (46.6%) | 8923 (30.5%) | Â |
2 | 1056 (3.6%) | 710 (2.4%) | Â |
3 | 1967 (6.7%) | 5946 (20.3%) | Â |
4 | 4418 (15.1) | 4123 (14.1%) | Â |
5 | 204 (0.7%) | 119 (0.4%) | Â |
6 | 112 (0.4%) | 136 (0.5%) | Â |
7 | 199 (0.7%) | 921 (3.2%) | Â |
8 | 14 (0.0%) | 30 (0.1%) | Â |
9 | 160 (0.5%) | 174 (0.6%) | Â |
10 | 162 (0.6%) | 757 (2.6%) | Â |
11 | 156 (0.5%) | 1083 (3.7%) | Â |
12 | 171 (0.6%) | 470 (1.6%) | Â |