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Table 2 Descriptive statistics of each drug cohorts

From: Using machine learning to develop a clinical prediction model for SSRI-associated bleeding: a feasibility study

 

Clopidogrel

Warfarin

Citalopram

Escitalopram

Fluoxetine

Fluvoxamine

Paroxetine

Sertraline

Vortioxetine

Combined SSRIs

Cohort size

2,159

1,855

3,151

2,597

2,719

117

1,100

4,052

149

10,362

Sex at birth, n (%)

 Male

1,248 (57.8)

909 (49.0)

2,052 (65.1)

697 (26.8)

834 (30.7)

42 (35.9)

364 (33.1)

1,332 (32.9)

37 (24.8)

4,390 (31.1)

 Female

867 (40.2)

906 (48.8)

1,040 (33.0)

1,862 (71.7)

1,847 (67.9)

74 (63.3)

721 (65.6)

2,668 (65.8)

110 (73.8)

9,508 (67.4)

Age, mean (SD)

 At index

63.1 (10.4)

60.2 (11.6)

50.4 (14.3)

50.2 (15.5)

48.1 (14.8)

43.3 (14.2)

51.6 (13.3)

49.0 (15.6)

48.8 (13.4)

49.4 (15.0)

 At survey

66.9 (10.2)

66.0 (11.6)

55.9 (15.1)

52.7 (16.0)

52.7 (15.8)

46.4 (15.1)

57.1 (14.1)

52.3 (16.3)

49.6 (13.6)

53.6 (15.8)

Race, n (%)

 White

1,571 (72.8)

1,370 (73.9)

2,273 (72.1)

2,003 (77.1)

1,999 (73.5)

92 (78.6)

768 (69.8)

2,928 (72.3)

121 (81.2)

10,341 (73.4)

 Black or African American

387 (17.9)

324 (17.5)

590 (18.7)

356 (13.7)

484 (17.8)

 ≤ 20

222 (20.2)

741 (18.3)

 ≤ 20

2,468 (17.5)

 Asian

 ≤ 20

 ≤ 20

 ≤ 20

27 (1.0)

 ≤ 20

0 (0.0)

 ≤ 20

36 (0.9)

 ≤ 20

104 (0.7)

Hispanic/Latino, n (%)

91 (4.2)

76 (4.1)

112 (3.6)

93 (3.6)

99 (3.6)

 ≤ 20

51 (4.6)

175 (4.3)

 ≤ 20

538 (3.8)

Highest education level, n (%)

 No high school degree

117 (5.4)

84 (4.5)

133 (4.2)

94 (3.6)

122 (4.5)

 ≤ 20

47 (4.3)

183 (4.5)

 ≤ 20

593 (4.2)

 High school graduate

479 (22.2)

407 (21.9)

713 (22.6)

490 (18.9)

578 (21.3)

 ≤ 20

262 (23.8)

871 (21.5)

27 (18.1)

3,018 (21.4)

 College 1–3 years

735 (34.0)

605 (32.6)

1,057 (33.5)

827 (31.8)

899 (33.1)

38 (32.5)

262 (23.8)

1,367 (33.7)

50 (33.6)

4,725 (33.5)

 College 4 years or more or advanced degree

771 (35.7)

710 (38.3)

1,163 (36.9)

1,139 (43.9)

1,061 (39.0)

56 (47.9)

385 (35.0)

1,456 (35.9)

68 (45.6)

5,384 (38.2)

Health insurance, n (%)

2,039 (94.4)

1,769 (95.4)

2,976 (94.5)

2,478 (95.4)

2,554 (93.9)

115 (98.3)

1,021 (92.8)

3,835 (94.6)

142 (95.3)

13,313 (94.4)

Employed for wages or self-employed, n (%)

492 (22.8)

405 (21.8)

1,103 (56.9)

1,107 (42.6)

1,045 (38.4)

41 (35.0)

372 (33.8)

1,429 (35.3)

52 (34.9)

5,246 (37.2)

Annual household income, n (%)

 Less 10 k

190 (8.8)

176 (9.5)

439 (13.9)

344 (13.3)

421 (15.5)

29 (24.8)

158 (14.4)

578 (14.3)

23 (15.4)

2,051 (14.6)

 10-25 k

404 (18.7)

330 (17.8)

561 (17.8)

424 (16.3)

504 (18.5)

26 (22.2)

237 (21.6)

700 (17.3)

34 (22.8)

2,525 (17.9)

 25-35 k

240 (11.1)

187 (10.1)

334 (10.6)

280 (10.8)

268 (9.9)

 ≤ 20

98 (8.9)

430 (10.6)

 ≤ 20

1,436 (10.2)

 35-50 k

247 (11.4)

226 (12.2)

337 (10.7)

258 (9.9)

291 (10.7)

 ≤ 20

116 (10.6)

417 (10.3)

 ≤ 20

1,454 (10.3)

 50-75 k

277 (12.8)

231 (12.5)

383 (12.2)

338 (13.0)

321 (11.8)

 ≤ 20

140 (12.7)

529 (13.1)

 ≤ 20

1,760 (12.5)

 75-100 k

172 (8.0)

157 (8.5)

279 (8.9)

235 (9.1)

233 (8.6)

 ≤ 20

88 (8.0)

355 (8.8)

 ≤ 20

1,238 (8.8)

 100-150 k

158 (7.3)

157 (8.5)

257 (8.2)

236 (9.1)

195 (7.2)

0 (0.0)

69 (6.3)

296 (7.3)

 ≤ 20

1,096 (7.8)

 150-200 k

40 (1.9)

37 (2.0)

84 (2.7)

84 (3.2)

79 (2.9)

 ≤ 20

25 (2.3)

111 (2.7)

 ≤ 20

393 (2.8)

 More 200 k

54 (2.5)

41 (2.2)

77 (2.4)

96 (3.7)

75 (2.8)

 ≤ 20

27 (2.5)

105 (2.6)

 ≤ 20

395 (2.8)

  1. Abbreviations: SD standard deviation, SSRIs selective serotonin reuptake inhibitors
  2. Results were reported in compliance with the AoU Data and Statistics Dissemination Policy prohibiting the display of participant counts ranging 1 to 20