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Table 2 The 17 rules extracted from the DT model to distinguish between acute and repeated supra-therapeutic (RST) acetaminophen exposures

From: Using a decision tree algorithm to distinguish between repeated supra-therapeutic and acute acetaminophen exposures

The patient is more likely to have acute acetaminophen exposure IF:

33 > age > 27 years

Abdominal pain is absent

AST, ALT < 1000

52.1% likelihood

27 > age > 23 years

Abdominal pain is absent

 

56.7% likelihood

23 > age > 19 years

AST, ALT < 100 or  >1000

Abdominal pain is absent

70.4% likelihood

23 > age > 19 years

AST, ALT < 100 or  >1000

Abdominal pain is present

52.0% likelihood

age < 19 years

1000 > AST, ALT > 100

 

60.4% likelihood

age < 19 years

AST, ALT < 100 or  >1000

Nausea is present

77.7% likelihood

age < 19 years

AST, ALT < 100 or  >1000

Nausea is absent

88.5% likelihood

The patient is more likely to have RSTI of acetaminophen IF:

age > 51 years

Drowsiness/lethargy is present

 

53.2% likelihood

age > 51 years

Drowsiness/lethargy is absent

1000 > AST, ALT > 100

89.2% likelihood

age > 51 years

Drowsiness/lethargy is absent

AST, ALT < 100 or  >1000

76.2% likelihood

51 > age > 33 years

Abdominal pain is absent

1000 > AST, ALT > 100

78.3% likelihood

51 > age > 33 years

Abdominal pain is present

 

83.1% likelihood

51 > age > 33 years

Abdominal pain is absent

AST, ALT < 100 or  >1000

60.6% likelihood

33 > age > 27 years

Abdominal pain is absent

AST, ALT > 1000

75.0% likelihood

33 > age > 27 years

Abdominal pain is present

 

78.2% likelihood

27 > age > 23 years

Abdominal pain is present

 

63.4% likelihood

23 > age > 19 years

1000 > AST, ALT > 100

 

53.7% likelihood

  1. ALT, alanine aminotransferase; AST, aspartate aminotransferase; RSTI, repeated supra-therapeutic ingestion