Design, implementation, and evaluation of the computer-aided clinical decision support system based on learning-to-rank: collaboration between physicians and machine learning in the differential diagnosis process

Table 1 Definitions of rare diseases for each country

Country	Prevalence	Source
The EU	< 1 person in 2000	EU research on rare diseases
Japan	Not defined	Act on Medical Care for Patients with Intractable Diseases
The UK	< 1 person in 2000	The UK Rare Diseases Framework
The US	< 50,000 persons in the US	Rare Diseases Act of 2002

ISSN: 1472-6947