Table 1 Demographic and clinical characteristics of the ALS populations included in the study
From: Leveraging process mining for modeling progression trajectories in amyotrophic lateral sclerosis
Features | PRO-ACT | ALS–BS | p-value | |
|---|---|---|---|---|
n |  | 5389 | 43 | – |
Sex | Female | 2018 (37.4) | 21 (48.8) | 0.123 |
Male | 3371 (62.6) | 22 (51.2) | Â | |
Onset site | Bulbar | 1122 (20.8) | 11 (25.6) | <0.01 * |
Spinal | 3875 (71.9) | 31 (72.1) | ||
Spinal and bulbar | 59 (1.1) | 1 (2.3) | ||
Other | 333 (6.2) | 0 (0.0) | ||
Age at onset | [years] | 55.26 ± 11.68 | 59.14 ± 10.84 | 0.034 |
FVC at baseline | % | 82.24 ± 17.94 | 96.47 ± 15.35 | <0.01 |
Weight at baseline | [kg] | 75.86 ± 15.79 | 68.85 ± 9.20 | 0.019 |
Total ALSFRS at baseline | [score/40] | 30.12 ± 5.47 | 36.12 ± 9.20 | <0.01 |
Disease duration | [days] | 1063.03 ± 456.22 | 1241.67 ± 722.13 | 0.201 |
Follow-up duration | [days] | 407.06 ± 175.27 | 931.49 ± 627.49 | <0.01 |
Follow-up visits |  | 12.74 ± 6.23 | 7.44 ± 2.80 | <0.01 |
Survival | Censored | 3967 (73.6) | 23 (53.5) | <0.01 |
| Â | Dead/Tracheostomized | 1442 (26.4) | 20 (46.5) | |