Table 3 Descriptive summary statistics for the validation dataset
Dependent: Outcome | Â | Painful_neuropathy | Painless_neuropathy | Total | p value |
|---|---|---|---|---|---|
EQ5D_Index | Median (IQR) | 0.6 (0.4 to 0.7) | 0.7 (0.6 to 0.8) | 0.7 (0.5 to 0.8) |  < 0.001 |
Depression_tscore | Median (IQR) | 54.7 (41.1 to 60.5) | 48.9 (41.0 to 55.9) | 52.1 (41.0 to 58.8) |  < 0.001 |
Anxiety_tscore | Median (IQR) | 51.7 (40.3 to 57.9) | 48.3 (40.3 to 54.1) | 51.4 (40.3 to 57.5) | 0.001 |
Sleep_Disturbance_tscore | Median (IQR) | 51.5 (49.4 to 54.2) | 52.0 (49.7 to 54.5) | 51.8 (49.6 to 54.4) | 0.128 |
Trauma | No | 107 (59.4) | 73 (65.8) | 180 (61.9) | 0.289 |
| Â | Yes | 66 (36.7) | 33 (29.7) | 99 (34.0) | Â |
| Â | (Missing) | 7 (3.9) | 5 (4.5) | 12 (4.1) | Â |
Hospital_stay | No | 144 (80.0) | 82 (73.9) | 226 (77.7) | 0.269 |
| Â | Yes | 16 (8.9) | 15 (13.5) | 31 (10.7) | Â |
| Â | (Missing) | 20 (11.1) | 14 (12.6) | 34 (11.7) | Â |
TIPIExtraversion | Median (IQR) | 4.0 (3.0 to 5.0) | 4.0 (3.5 to 5.5) | 4.0 (3.0 to 5.0) | 0.077 |
TIPIAgreeableness | Median (IQR) | 5.0 (4.0 to 6.0) | 5.0 (4.5 to 6.0) | 5.0 (4.0 to 6.0) | 0.161 |
TIPIConscientiousness | Median (IQR) | 5.5 (4.5 to 6.5) | 5.5 (4.1 to 6.5) | 5.5 (4.5 to 6.5) | 0.600 |
TIPIEmotionalStability | Median (IQR) | 4.5 (4.0 to 5.5) | 5.0 (4.0 to 6.5) | 4.5 (4.0 to 6.0) | 0.027 |
TIPIOpenness | Median (IQR) | 4.5 (3.5 to 5.5) | 5.0 (4.0 to 6.0) | 4.5 (4.0 to 5.5) | 0.047 |
Ever_smoked_status | No | 71 (39.4) | 44 (39.6) | 115 (39.5) | 1.000 |
| Â | Yes | 108 (60.0) | 66 (59.5) | 174 (59.8) | Â |
| Â | (Missing) | 1 (0.6) | 1 (0.9) | 2 (0.7) | Â |
Alcohol_consumption | Never | 60 (33.3) | 27 (24.3) | 87 (29.9) | 0.358 |
| Â | Less than 1Â day per month | 45 (25.0) | 30 (27.0) | 75 (25.8) | Â |
| Â | 1 to 3Â days per month | 30 (16.7) | 19 (17.1) | 49 (16.8) | Â |
| Â | 1 or 2Â days per week | 16 (8.9) | 18 (16.2) | 34 (11.7) | Â |
| Â | 3 or 4Â days per week | 16 (8.9) | 8 (7.2) | 24 (8.2) | Â |
| Â | Daily or almost daily | 11 (6.1) | 8 (7.2) | 19 (6.5) | Â |
| Â | (Missing) | 2 (1.1) | 1 (0.9) | 3 (1.0) | Â |
Alcohol_consumption_likert | Median (IQR) | 1.0 (0.0 to 2.0) | 1.0 (1.0 to 3.0) | 1.0 (0.0 to 3.0) | 0.134 |
Alcohol_status | No | 60 (33.3) | 27 (24.3) | 87 (29.9) | 0.130 |
| Â | Yes | 118 (65.6) | 83 (74.8) | 201 (69.1) | Â |
| Â | (Missing) | 2 (1.1) | 1 (0.9) | 3 (1.0) | Â |
PCS_score | Median (IQR) | 11.0 (5.0 to 22.5) | 5.0 (1.0 to 15.0) | 8.5 (4.0 to 20.0) |  < 0.001 |
MNSI_score | Median (IQR) | 5.0 (4.0 to 6.0) | 3.0 (3.0 to 4.0) | 4.0 (3.0 to 6.0) |  < 0.001 |
DN4_score | Median (IQR) | 4.0 (3.0 to 5.0) | 1.0 (0.0 to 1.0) | 3.0 (2.0 to 5.0) |  < 0.001 |
Age | Median (IQR) | 68.0 (63.0 to 77.0) | 69.0 (63.5 to 76.0) | 69.0 (63.0 to 77.0) | 0.590 |
Gender | Female | 66 (36.7) | 38 (34.2) | 104 (35.7) | 0.742 |
| Â | Male | 113 (62.8) | 73 (65.8) | 186 (63.9) | Â |
| Â | (Missing) | 1 (0.6) | 0 (0.0) | 1 (0.3) | Â |
BMI | Median (IQR) | 31.4 (28.3 to 36.4) | 30.8 (27.2 to 34.4) | 31.2 (27.8 to 35.3) | 0.204 |
HBA1C | Median (IQR) | 7.5 (6.8 to 8.9) | 7.4 (6.7 to 8.4) | 7.4 (6.7 to 8.7) | 0.311 |
Diabetes_Duration | Median (IQR) | 15.0 (12.0 to 19.5) | 16.0 (12.0 to 21.5) | 15.0 (12.0 to 20.0) | 0.921 |
Cholesterol | Median (IQR) | 3.9 (3.5 to 4.4) | 3.9 (3.4 to 4.4) | 3.9 (3.4 to 4.4) | 0.700 |
LDL | Median (IQR) | 2.0 (1.5 to 2.5) | 2.0 (1.6 to 2.5) | 2.0 (1.5 to 2.5) | 0.591 |
HDL | Median (IQR) | 1.1 (0.9 to 1.3) | 1.1 (0.9 to 1.3) | 1.1 (0.9 to 1.3) | 0.948 |
Creatinine | Median (IQR) | 79.5 (64.0 to 99.0) | 82.0 (64.5 to 98.0) | 80.0 (64.0 to 99.0) | 0 .568 |
Triglycerides | Median (IQR) | 1.8 (1.4 to 2.7) | 1.7 (1.3 to 2.4) | 1.8 (1.3 to 2.6) | 0.180 |