Table 21 Examples of publications considering pathways from a clinical context perspective

Williams et al. [125]

Weber et al. [126]

Boytcheva et al. [127]

Dauxais et al. [128]

Guyet et al. [129]

Clinical process models utilising prescription data, focussing on therapeutic decisions [125], polypharmacy [126], chronic comorbidities [127], and drug interactions in chronic disease [128, 129]. [126] identifies potential strong drug interactions in nearly 40% of patients, while [127] finds a statistical association between a particular initial treatment and a subsequent comorbidity. [128, 129] identify a particular change of medication associated with a subsequent acute episode in previously stable patients

Dabek et al. [130]

Visualisation tool allowing exploration of treatment pathways and comorbidities of a very large patient cohort

Blum et al. [132]

Neumuth et al. [133, 134]

Clinical process models deriving workflows from transcribed video. [131] assesses utility of a checklist in improving guideline conformance, while [132,133,134] derive consensus surgical workflows. These are linked to video in [132], and are editable and mergeable in [133, 134]

Rojas and Capurro [135]

Chen et al. [136]

Movahedi et al. [137]

Patterns of treatment [135, 136] or adverse events [137]. [137] further determines clinically meaningful Markov Chain models of grouped adverse events

Riaño et al. [138]

State-Decision-Action model, where clinical practice is mined from treatment records to construct a data-derived clinical algorithm