Table 1 The rules for preprocessing of patient data

1

The patient's onset time and arrival time cannot be missing

Exact minute

2

The patient's onset time is earlier than the arrival time

3

The start time of orders is later than patient's arrival time

4

Patient's arrival time is earlier than the time arrival of neurology department

Applicable to cooperative hospitals

5

If the patient has more than one thrombolytic drug order, we will choose the earliest order to determine the start time of thrombolytic therapy

Thrombolytic drugs include rt-PA and urokinase

6

The time of arrival of neurology department will be determined by the first order issued after admission

7

Range of rt-PA dosage: 20 mg ≤ n ≤ 300 mg

8

Range of door-to-needle time: 0 < n ≤ 360 min

9

Range of time from onset to start of thrombolytic therapy: 0 < n ≤ 360 min