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Table 4 The accuracy of influenza coding (ICD10 +) among patients with PCR + : A sub-group analysis by selected characteristics and test result availability

From: Evaluation of the accuracy of diagnostic coding for influenza compared to laboratory results: the availability of test results before hospital discharge facilitates improved coding accuracy

 

Test results received before discharge

(n = 2450)

Test results received after discharge

(n = 309)

PCR+

ICD10+

Sensitivity

(95% CI)

Adjusted ORa

(95% CI); P-value

PCR+

ICD10+

Sensitivity

(95% CI)

Adjusted ORa

(95% CI); P-value

Type of laboratory test

        

 Rapid PCRb

1551

1498

96.6 (95.6–97.4)

2.1 (1.3–3.5); P = 0.01

20

6

30.0 (11.9–54.3)

1.6 (0.4–6.4); P = 0.46

 Multiplex PCR

899

782

87.0 (84.6–89.1)

Ref

289

95

32.9 (27.5–38.6)

Ref

Season

        

 Influenza

2132

2003

94.0 (92.9–94.9)

1.5 (1.0–2.3); P = 0.04

220

67

30.5 (24.4–37.0)

0.7 (0.4–1.2); P = 0.19

 Non-influenza

318

277

87.1 (82.9–90.6)

Ref

89

34

38.2 (28.1–49.1)

Ref

Hospital

        

 A

675

644

95.4 (93.5–96.9)

4.1 (2.0–8.5); P < 0.01

121

32

26.4 (18.8–35.2)

0.5 (0.2–1.4); P = 0.20

 B

472

419

88.8 (85.6–91.5)

1.6 (0.8–3.3); P = 0.16

94

29

30.9 (21.7–41.2)

0.6 (0.2–1.5); P = 0.28

 C

344

325

94.5 (91.5–96.6)

3.1 (1.4–6.6); P < 0.01

39

19

48.7 (32.4–65.2)

1.2 (0.5–3.2); P = 0.69

 D

483

468

96.9 (94.9–98.3)

3.7 (1.5–9.3); P < 0.01

10

2

20.0 (2.5–55.6)

0.2 (0.03–1.8); P = 0.17

 E

219

208

95.0 (91.2–97.5)

2.3 (0.8–6.3); P = 0.12

5

1

20.0 (0.5–71.6)

0.2 (0.02–3.6); P = 0.30

 F

126

125

99.2 (95.6–99.9)

12.9 (1.6–106.7); P = 0.02

 G

131

91

69.5 (60.8–77.2)

Ref

40

18

45.0 (29.3–61.5)

Ref

Setting where the test was ordered

        

 EDc

1492

1410

94.5 (93.2–95.6)

1.4 (0.9–2.0); P = 0.06

192

69

35.9 (29.2–43.2)

1.9 (1.1–3.5); P = 0.03

 Inpatient

958

870

90.8 (88.9–92.6)

Ref

117

32

27.4 (19.5–36.4)

Ref

  1. aEach analysis was adjusted for patient age, Charlson comorbidity index, year of admission, hospital length of stay and three other variables in this table
  2. b111 patients who were ordered both rapid and multiplex PCR were included in this group for the purpose of this analysis
  3. cThis group included 22 patients who were ordered an influenza test both in ED and inpatient wards