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Table 3 Top 10 OR results for 4-drug combination vs. 2-drug: with Bonferroni correction, a significant p is 2.61E-7

From: Mining and visualizing high-order directional drug interaction effects using the FAERS database

4-drug combination2-drug combinationORp-value
Gadobenate Dimeglumine, Gadodiamide, Gadoteridol, PrednisoneGadobenate Dimeglumine, Prednisone270.168.81E-09
Pamidronate, Sulfamethoxazole, Trimethoprim, ZoledronatePamidronate, Sulfamethoxazole85.714.87E-23
Doxorubicin, Pamidronate, Vincristine, ZoledronateDoxorubicin, Vincristine41.742.02E-129
Dexamethasone, Doxorubicin, Oxycodone, VincristineDoxorubicin, Vincristine36.772.59E-92
Dexamethasone, Doxorubicin, Pamidronate, VincristineDoxorubicin, Vincristine30.995.38E-108
Dexamethasone, Doxorubicin, Vincristine, ZoledronateDoxorubicin, Vincristine30.526.37E-112
Acetaminophen, Diphenhydramine, Prochlorperazine, ZoledronateDiphenhydramine, Prochlorperazine29.157.61E-62
Docetaxel, Oxycodone, Prochlorperazine, ZoledronateDocetaxel, Prochlorperazine28.959.23E-79
Acetaminophen, Cyclophosphamide, Doxorubicin, PamidronateCyclophosphamide, Doxorubicin27.761.79E-85
Docetaxel, Furosemide, Oxycodone, ZoledronateDocetaxel, Furosemide27.325.22E-58