Table 4 Signal detection results related to Potassium Magnesium Aspartate, Levofloxacin Hydrochloride and Cefazolin
Drug (frequency) | ADR | DECs’ frequency | IC025 of non-stratification | IC025 of stratification |
|---|---|---|---|---|
Potassium Magnesium Aspartate (2043) | pruritus | 65 | −2.42 | 1 |
anaphylactoid reaction | 63 | −0.67 | 0.94 | |
headache | 54 | −1.17 | 0.64 | |
dyspnoea | 40 | −0.25 | 0.48 | |
cyanosis | 11 | −0.59 | 0.06 | |
Levofloxacin Hydrochloride (111,335) | larynx oedema | 69 | −0.32 | 4.04 |
Infusion reaction | 66 | −0.93 | 3.76 | |
skin discolouration | 41 | −3.46 | 3.7 | |
vesicular rash | 54 | −1.46 | 3.02 | |
tachycardia | 66 | −2.37 | 2.53 | |
agitation | 75 | −0.52 | 2.37 | |
asthma | 29 | −2.2 | 2.3 | |
application site pain | 114 | −0.39 | 2.04 | |
arrhythmia | 26 | −3.04 | 1.61 | |
ecphysesis | 121 | −1.18 | 1.38 | |
Cefazolin (15,105) | injection site rash | 67 | −0.12 | 2.27 |
larynx oedema | 18 | −0.21 | 1.47 | |
ecphysesis | 44 | −0.17 | 1.41 | |
injection site pruritus | 30 | −1.95 | 1.39 | |
haematuria | 22 | −0.99 | 1.07 | |
oedema periorbital | 31 | −0.61 | 1.06 | |
anaesthesia local | 57 | −1.21 | 1.05 | |
cutireaction | 43 | −1.18 | 1.04 | |
diarrhoea | 72 | −3.34 | 0.9 | |
sweating increased | 79 | −0.48 | 0.9 |