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Table 4 The discriminative ability of PSA, PCPT, PBCG, ERSPC and IPRC using the areas under the curve (AUC) and 95% confidence interval of the calculated probabilities. The p-values indicate if the difference between each method and IPRC is significant

From: A risk calculator to inform the need for a prostate biopsy: a rapid access clinic cohort

Models Prostate cancer (n = 4801) High grade cancer (n = 2548)
AUC 95% CI p-value AUC 95% CI p-value
PSA 0.5948 0.5789–0.6107 P < 0.001 0.6623 0.6413–0.6832 P < 0.001
PCPT 0.6304 0.6148–0.6460 P < 0.001 0.6804 0.6597–0.7012 0. 005
PBCG 0.6528 0.6375–0.6681 P < 0.001 0.7185 0.6988–0.7381 0.839
ERSPC 0.6502 0.6349–0.6655 P < 0.001 0.7140 0.6942–0.7338 0.604
IPRC 0.6741 0.6591–0.6890 0.7214 0.7018–0.7409