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Table 2 Clinical Characteristics of patients whom their prostate volume is recorded

From: A risk calculator to inform the need for a prostate biopsy: a rapid access clinic cohort

 

All patients with prostate volume (n = 2970)

PCa patients with prostate volume (n = 1689)

PCa

No PCa

P-value

High grade PCa

Low grade PCa

P-value

Patients

1689 (57%)

1281 (43%)

 

1022 (61%)

667 (39%)

 

Median Age (mean)

64.89 (64.05)

63.00 (62.00)

< 0.001 (< 0.001)

65.00 (64.68)

64.00 (63.09)

< 0.001 (< 0.001)

Family history of PCa

 Yes

129 (8%)

91 (7%)

0.741

83 (8%)

46 (7%)

0.192

 Not recorded

1186 (70%)

894 (70%)

 

701 (69%)

485 (73%)

 

 No

374 (22%)

296 (23%)

 

238 (23%)

136 (20%)

 

Median PSA (mean)

7.19 (19.45)

6.42 (7.45)

< 0.001 (< 0.001)

7.82 (27.43)

6.30 (7.23)

< 0.001 (< 0.001)

DRE

 Normal

735 (44%)

706 (55%)

< 0.001

361 (35%)

374 (56%)

< 0.001

 Not recorded

241 (14%)

286 (22%)

 

143 (14%)

98 (15%)

 

 Abnormal

713 (42%)

289 (23%)

 

195 (51%)

195 (29%)

 

Previous negative biopsy

 Yes

277 (16%)

303 (24%)

< 0.001

113 (11%)

164 (25%)

< 0.001

 No

1412 (84%)

978 (76%)

 

909 (89%)

503 (75%)

 

Median Prostate volume (mean)

35 (39.9)

45 (51.9)

< 0.001 (< 0.001)

34.1 (38.5)

37.3 (42.0)

< 0.001 (0.001)

Biopsy Gleason Score

 Gleason 6

667 (40%)

   

667 (100%)

 

 Gleason 7

659 (39%)

  

659 (64%)

  

 Gleason 8

222 (13%)

  

222 (22%)

  

 Gleason 9

124 (7%)

  

124 (12%)

  

 Gleason 10

17 (1%)

  

17 (2%)