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Table 2 Clinical Characteristics of patients whom their prostate volume is recorded

From: A risk calculator to inform the need for a prostate biopsy: a rapid access clinic cohort

  All patients with prostate volume (n = 2970) PCa patients with prostate volume (n = 1689)
PCa No PCa P-value High grade PCa Low grade PCa P-value
Patients 1689 (57%) 1281 (43%)   1022 (61%) 667 (39%)  
Median Age (mean) 64.89 (64.05) 63.00 (62.00) < 0.001 (< 0.001) 65.00 (64.68) 64.00 (63.09) < 0.001 (< 0.001)
Family history of PCa
 Yes 129 (8%) 91 (7%) 0.741 83 (8%) 46 (7%) 0.192
 Not recorded 1186 (70%) 894 (70%)   701 (69%) 485 (73%)  
 No 374 (22%) 296 (23%)   238 (23%) 136 (20%)  
Median PSA (mean) 7.19 (19.45) 6.42 (7.45) < 0.001 (< 0.001) 7.82 (27.43) 6.30 (7.23) < 0.001 (< 0.001)
DRE
 Normal 735 (44%) 706 (55%) < 0.001 361 (35%) 374 (56%) < 0.001
 Not recorded 241 (14%) 286 (22%)   143 (14%) 98 (15%)  
 Abnormal 713 (42%) 289 (23%)   195 (51%) 195 (29%)  
Previous negative biopsy
 Yes 277 (16%) 303 (24%) < 0.001 113 (11%) 164 (25%) < 0.001
 No 1412 (84%) 978 (76%)   909 (89%) 503 (75%)  
Median Prostate volume (mean) 35 (39.9) 45 (51.9) < 0.001 (< 0.001) 34.1 (38.5) 37.3 (42.0) < 0.001 (0.001)
Biopsy Gleason Score
 Gleason 6 667 (40%)     667 (100%)  
 Gleason 7 659 (39%)    659 (64%)   
 Gleason 8 222 (13%)    222 (22%)   
 Gleason 9 124 (7%)    124 (12%)   
 Gleason 10 17 (1%)    17 (2%)