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Table 1 Median IQR and P-Value of features corrected for all acquisition parameters, age and gender P -values of the Mann Whitney 2 samples test across IDH status and Grade are reported

From: Machine learning assisted DSC-MRI radiomics as a tool for glioma classification by grade and mutation status

  WT IDH P WT vs IDH Grade II Grade III Grade IV Comparisons
Median IQR Median IQR Median IQR Median IQR Median IQR II vs III II vs IV III vs IV
Volume 48,462.5 48,106 46,925 65,232.5 0.091 45,811 65,213 39,962.5 51,400.5 52,035.5 51,967.5 0.311 0.468 0.238
Surface 10,246 9723.750 9402 9677 0.445 8756 9352 8047.5 9546.25 10,631.5 9711.75 0.367 0.053 0.143
SAV 0.225 0.080 0.200 0.08 < 0.0005 0.198 0.083 0.218 0.093 0.224 0.084 0.010 < 0.0005 0.252
NonCompactness 21.008 10.766 18.942 9.433 0.002 17.992 7.745 19.651 10.69 21.884 11.397 0.021 < 0.0005 0.063
Mean 0.014 0.550 −0.199 0.592 < 0.0005 −0.185 0.517 −0.158 0.568 0.029 0.582 0.338 < 0.0005 0.001
Skewness −0.183 0.802 0.198 0.792 < 0.0005 0.209 0.79 0.165 0.781 −0.232 0.756 0.157 < 0.0005 < 0.0005
TabKurtosis −1.348 3.540 0.344 3.853 < 0.0005 0.11 3.737 0.471 4.501 −1.527 3.468 0.433 < 0.0005 < 0.0005
Min 0.008 0.355 −0.026 0.37 0.030 −0.001 0.425 −0.021 0.33 −0.006 0.385 0.342 0.341 0.198
Max −0.089 1.175 −0.053 1.316 0.470 −0.075 1.248 −0.013 1.296 −0.096 1.195 0.314 0.481 0.334
STD 0.008 0.418 −0.055 0.345 0.002 −0.04 0.347 −0.086 0.356 0.006 0.417 0.167 0.025 0.002
P1 0.031 0.389 −0.046 0.416 0.035 −0.01 0.405 −0.021 0.409 0.021 0.401 0.335 0.264 0.168
P5 0.033 0.377 −0.049 0.426 0.025 −0.036 0.409 0.016 0.423 0.027 0.391 0.461 0.095 0.161
P25 0.061 0.431 −0.093 0.45 < 0.0005 − 0.049 0.458 − 0.045 0.421 0.039 0.463 0.184 0.001 0.030
TaP50 0.044 0.499 −0.194 0.555 < 0.0005 −0.158 0.516 −0.152 0.566 0.052 0.561 0.146 < 0.0005 0.003
P75 0.018 0.798 −0.295 0.737 < 0.0005 −0.278 0.689 −0.247 0.755 0.028 0.842 0.266 < 0.0005 < 0.0005
P95 0.084 1.312 −0.376 1.350 < 0.0005 −0.216 1.403 −0.405 1.278 0.093 1.351 0.207 0.003 0.001
P99 0.186 1.405 −0.211 1.529 0.001 −0.068 1.568 −0.31 1.451 0.186 1.37 0.116 0.083 0.002
ASM −0.004 0.008 −0.002 0.0100 0.001 −0.002 0.01 −0.003 0.006 −0.004 0.009 0.281 0.001 0.007
Contrast −4.890 18.634 −4.279 15.036 0.062 −3.672 17.134 −5.711 13.839 −4.179 18.677 0.123 0.263 0.045
Correlation −1.113 8.802 1.907 8.196 < 0.0005 0.828 8.248 2.729 7.336 −1.113 9.016 0.107 0.001 < 0.0005
SumSquare −19.125 597.816 −225.235 594.281 < 0.0005 −209.191 525.299 − 177.068 606.613 18.931 630.678 0.393 < 0.0005 0.001
SumAverage 0.444 10.685 −3.779 11.507 < 0.0005 −3.615 10.26 −2.983 10.843 0.505 11.502 0.338 < 0.0005 0.001
IDifferenceMoment −0.023 0.118 0.016 0.112 < 0.0005 0.02 0.125 0.012 0.118 − 0.019 0.112 0.112 < 0.0005 0.002
Sum Entropy −0.086 0.406 0.039 0.412 < 0.0005 0.039 0.409 0.07 0.424 −0.082 0.397 0.412 < 0.0005 0.001
Entropy 0.156 0.747 −0.09 0.717 < 0.0005 −0.09 0.663 −0.119 0.805 0.176 0.688 0.277 < 0.0005 0.001
Difference Variance −0.049 0.186 −0.043 0.150 0.062 −0.037 0.171 −0.057 0.138 −0.042 0.187 0.123 0.263 0.045
Sum Variance 9.638 2522.443 − 905.249 2537.186 < 0.0005 − 804.524 2172.045 −735.281 2522.304 71.102 2654.762 0.366 < 0.0005 0.001
difference Entropy 0.043 0.376 −0.044 0.336 < 0.0005 − 0.038 0.353 − 0.031 0.346 0.062 0.347 0.389 0.001 0.005
IMC1 −0.012 0.073 −0.001 0.062 0.053 0.005 0.053 −0.008 0.061 −0.011 0.068 0.020 0.012 0.429