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Table 1 Top DE-miRNAs from Case vs. control (18 DE-miRs total) and Treatment vs. case (8 DE-miRs total)

From: Expression alteration of microRNAs in Nucleus Accumbens is associated with chronic stress and antidepressant treatment in rats

Case vs. control Treatment vs. case
miRNA log2 FC Relevance to Neuropsychiatric disease Ref miRNA log2FC Relevance to Neuropsychiatric disease Ref
miR-1298 1.70 NA   miR-7a-5p −1.10 NA  
miR-139-5p 1.28 May Marks sensitivity to stress [22] miR-181a-2-3p 1.05 Related to Cerebral cavernous malformations [23]
miR-139-3p 1.41 ↓by Nerve Growth Factor treatment [24] miR-200a-3p 1.02 Mediate antidepressant-like effects in stressed rat [25]
miR-34c-5p 1.23 ↓in blood&brain of MDD patients [26, 27] miR-214-3p −2.05 adjusts Depressive-like Behaviors [28]
miR-448-3p 1.61 NA   miR-32-3p −1.24 NA  
miR-204-5p 1.07 Suppressed by morphine [29] miR-6215 4.16 NA  
miR-10b-5p −1.29 Related to Parkinson disease [30] miR-653-5p − 1.02 NA  
miR-214-3p 2.02 adjusts Depressive-like Behaviors [31] miR-10b-5p 1.36 Related to Parkinson disease [30]
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BMC Medical Informatics and Decision Making

ISSN: 1472-6947

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