Combining entity co-occurrence with specialized word embeddings to measure entity relation in Alzheimer’s disease

Table 14 Gene–phenotype ranking by number of common-phenotype genes (PKDE4J)

Entity A	Entity C (Gene Only)	Phenotype	Phenotype-Related Gene	Common Phenotype Genes
Alzheimers disease	CD36	Platelet glycoprotein IV deficiency	CD36	17
		Macrothrombocytopenia	–
		Coronary heart disease	CD36
		Malaria, cerebral	ACKR1, FCGR2A, FCGR2B, FCGR2A, FCGR2B, CR1, GYPC, CISH, GYPB, GYPA, TNF, HBB, TIRAP, NOS2A, SLC4A1, ICAM1,G6PD, CD36
Alzheimers disease	IL10	Graft-versus-host disease	IL10	13
		HIV-1	CXCR1, CX3CR1, TLR3, HLAC, CXCL12, IFNG, IL4R, CCL3L1, CCL2, CCL11, CCL3, CD209, KIR3DL1, IL10
		Rheumatoid arthritis	–
Alzheimers disease	ABCA1	HDL deficiency	APOA1, ABCA1	2
		Tangier disease	ABCA1
		Coronary artery disease, familial	LDLR, ABCA1

ISSN: 1472-6947