Table 2 Psychotropics prescribed to patients in 2000 and 2016 in three nursing homes with 386 and 416 patients the respective years
2000 | 2016 | p-value | |||
|---|---|---|---|---|---|
Patients n (%) | n (%) | Patients n (%) | n (%) | ||
All patients | 386 (100.0) | 416 (100.0) | |||
Antidepressants | 97 (25.1) | 170 (40.9) | < 0.001 | ||
Antipsychotics | 91 (23.6) | 130 (31.3) | 0.015 | ||
Anxiolytics-hypnotics | 102 (26.4) | 268 (64.4) | < 0.001 | ||
Antiepileptics | 29 (7.5) | 49 (11.8) | 0.042 | ||
One or more drugs | 230 (59.6) | 335 (80.5) | < 0.001 | ||
Antidepressants | 97 (42.2) | 170 (50.7) | 0.045 | ||
Antipsychotics | 91 (39.6) | 130 (38.8) | 0.856 | ||
Anxiolytics-hypnotics | 102 (44.3) | 268 (80.0) | < 0.001 | ||
Antiepileptics | 29 (12.6) | 49 (14.6) | 0.494 | ||
Two or more drugs | 94 (24.4) | 233 (56.0) | < 0.001 | ||
Antidepressants | 53 (56.4) | 151 (64.8) | 0.155 | ||
Antipsychotics | 53 (56.4) | 114 (48.9) | 0.222 | ||
Anxiolytics-hypnotics | 65 (69.1) | 203 (87.1) | < 0.001 | ||
Antiepileptics | 14 (14.9) | 47 (20.2) | 0.347 | ||
Three or more drugs | 24 (6.2) | 123 (29.6) | < 0.001 | ||
Antidepressants | 17 (70.8) | 97 (78.9) | 0.389 | ||
Antipsychotics | 17 (70.8) | 72 (58.5) | 0.260 | ||
Anxiolytics-hypnotics | 20 (83.3) | 116 (94.3) | 0.062 | ||
Antiepileptics | 6 (25.0) | 35 (28.5) | 0.730 | ||
≥ 1 interaction | 63 (16.3) | 146 (35.1) | < 0.001 | ||
Antidepressants | 43 (68.3) | 134 (91.8) | < 0.001 | ||
Antipsychotics | 38 (60.3) | 63 (43.2) | 0.023 | ||
Anxiolytics-hypnotics | 36 (57.1) | 124 (84.9) | < 0.001 | ||
Antiepileptics | 11 (17.5) | 29 (19.9) | 0.347 | ||