Table 2 Bivariate associations between linear outcome (maximum creatinine during Day 2 and Day 3) and binary outcome (AKI) and Predictors

 (M: 1,F: 0)

0.2135

< 0.001

[0.206,0.221]

1.23

< 0.001

[1.144,1.318]

Age (yr)

0.0019

< 0.001

[0.002,0.002]

1.02

< 0.001

[1.016,1.020]

 African-American

ref

ref

ref

ref

ref

ref

 Caucasian

−0.0706

< 0.001

[−0.086,-0.055]

1.12

0.106

[0.976,1.294]

 Hispanic

−0.1026

< 0.001

[− 0.128,-0.077]

0.73

0.014

[0.566,0.938]

 Other

−0.0585

< 0.001

[− 0.076,-0.041]

1.33

< 0.001

[1.136,1.552]

Systolic BP Min (mmHg)

−0.0011

< 0.001

[−0.001,-0.001]

0.98

< 0.001

[0.976,0.980]

Systolic BP Mean (mmHg)

−0.0005

< 0.001

[−0.001,0.000]

0.98

< 0.001

[0.982,0.987]

Diastolic BP Min (mmHg)

−0.0003

0.067

[− 0.001,0.000]

0.98

< 0.001

[0.980,0.986]

Diastolic BP Mean (mmHg)

−0.0009

< 0.001

[−0.001,0.001]

0.98

< 0.001

[0.971,0.978]

Temperature Max (Celsius)

−0.0035

0.190

[−0.009,0.002]

1.04

0.089

[0.994,1.089]

SpO2 Min (%)

−0.0014

< 0.001

[−0.002,-0.001]

0.99

< 0.001

[0.983,0.991]

SpO2 Mean (%)

−0.0028

0.010

[−0.005,-0.001]

1.08

< 0.001

[1.055,1.098]

Bicarbonate Level Min (mg/dL)

−0.0049

< 0.001

[−0.006,-0.004]

0.94

< 0.001

[0.934,0.949]

Creatinine Level Minimum (mg/dL)

0.9479

< 0.001

[0.933,0.963]

–

–

–

Creatinine Level Max (mg/dL)

0.9340

< 0.001

[0.921,0.947]

3.20

< 0.001

[2.743, 3.737]

Hemoglobin Level Min (g/dL)

−0.0048

< 0.001

[− 0.007,-0.003]

0.77

< 0.001

[0.759,0.787]

Platelet Count Min (K/μL)

− 0.0004

< 0.001

[− 0.000,0.000]

1.00

< 0.001

[0.996,0.997]

Potassium Level Max (mg/dL)

0.0837

< 0.001

[0.079,0.089]

1.90

< 0.001

[1.824,1.984]

Partial Thromboplastin Time Min (s)

0.0020

< 0.001

[0.002,0.002]

1.01

< 0.001

[1.010,1.015]

Partial Thromboplastin Time Max (s)

0.0012

< 0.001

[0.001,0.001]

1.01

< 0.001

[1.008,1.010]

International Normalized Ratio Min

0.0213

< 0.001

[0.013,0.030]

1.04

0.266

[0.970,1.118]

International Normalized Ratio Max

0.0274

< 0.001

[0.022,0.033]

1.21

< 0.001

[1.158,1.260]

Prothrombin Time Min (s)

0.0032

< 0.001

[0.002,0.004]

1.01

0.194

[0.997,1.015]

Prothrombin Time Max (s)

0.0042

< 0.001

[0.003,0.005]

1.03

< 0.001

[1.021,1.033]

Blood Urea Nitrogen Level Max (mg/dL)

0.0088

< 0.001

[0.008,0.009]

1.01

< 0.001

[1.009,1.017]

White Blood Cell Count Max (K/μL)

0.0008

< 0.001

[0.000,0.001]

1.01

< 0.001

[1.010,1.018]

Calcium Level Min (mg/dL)

0.0245

< 0.001

[0.019,0.030]

0.72

< 0.001

[0.685,0.749]

Mechanical Ventilation (Yes 1/No 0) - N, %

0.0618

< 0.001

[0.054,0.070]

3.04

< 0.001

[2.816,3.275]

Estimated Glomerular Filtration Rate (eGFR)

−0.0025

< 0.001

[−0.003,-0.002]

1.00

< 0.001

[1.004,1.005]