Modelling cancer outcomes of bone metastatic patients: combining survival data with N-Telopeptide of type I collagen (NTX) dynamics through joint models

Table 3 Coefficents and p-values for the multivariate Cox regression model

Age diagnosis		Sex		ExtraMets			NTX
Value	p-value	Value	p-value	Value	p-value	Type	Value	p-value
0.0220	0.0088	0.2485	0.3073	0.7823	0.0017	NTX3	0.0002	0.5875 ^a
0.0209	0.0127	0.2421	0.3155	0.7393	0.0034	log(NTX3)	0.1211	0.2165 ^a
0.0225	0.0069	0.2214	0.3614	0.7752	0.0020	NTX3 >100	0.1448	0.5831 ^a
0.0184	0.1513	0.3709	0.3663	0.6223	0.0775	NTX12	0.0010	0.2225 ^b
0.0177	0.1633	0.3647	0.3756	0.5563	0.1314	log(NTX12)	0.1638	0.2556 ^b
0.0164	0.1910	0.5141	0.2312	0.4947	0.1806	NTX12 >64	0.6936	0.0781 ^b

The NTX type column refers to the type of NTX feature used in each model fit. ^a: Analysis using only patients with NTX3 measurement (106 patients with 86 events). ^b: Analysis using only patients with NTX12 measurement (51 patients with 41 events)

ISSN: 1472-6947