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Table 6 Randomly chosen example association rules obtained for queries in Tables 4 and 5 and supporting literature

From: Query-constraint-based mining of association rules for exploratory analysis of clinical datasets in the National Sleep Research Resource

Variable/Dataset Description Antecedent Consequent Supporting
     Literature
htnhist/HeartBEAT hypertension-history diabetes mellitus-history hypercholesterolemia-history None
htnhist/HeartBEAT hypertension-history diabetes mellitus-history habitual snoring [2224]
tzd/SHHS thiazolidinedione hypertension-history sulfonylurea, diabetes mellitus-history None
tzd/SHHS thiazolidinedione hmg-coa reductase inhibitor sulfonylurea, habitual snoring, None
    nonsteroidal anti-inflammatory drug,  
    hypercholesterolemia  
biguanide/SHHS biguanide hypercholesterolemia sulfonylurea, hypertension-history, None
    hmg-coa reductase inhibitor  
biguanide/SHHS biguanide hypertension-history sulfonylurea, hmg-coa reductase inhibitor, None
    hypercholesterolemia  
chfhist/SHHS congestive heart failure-history angina pectoris myocardial infarction-history [32, 33]
chfhist/SHHS congestive heart failure-history loop diuretic hypertension-history, [1921]
    angiotensin converting enzyme inhibitor  
typicalantipsychot/HCHS Typical Antipsychotic coronary artery disease-history tricyclic antidepressant None
typicalantipsychot/HCHS Typical Antipsychotic diabetes mellitus-history tricyclic antidepressant [3436]
arb/SHHS angiotensin 2 receptor blocker chronic obstructive pulmonary nonsteroidal anti-inflammatory drug, [3740]
   disease/emphysema-history habitual snoring, hypertension-history  
arb/SHHS angiotensin 2 receptor blocker hypertension-history nonsteroidal anti-inflammatory drug,  
    habitual snoring None
cadhist/HCHS coronary artery disease-history angiotensin converting thiazide diuretic, hypertension-history, [22, 25, 26]
   enzyme inhibitor diabetes mellitus-history  
cadhist/HCHS coronary artery disease-history persistent wheezing hypertension-history None
potassiumsalt/SHHS potassium salt loop diuretic habitual snoring, hypertension-history None
potassiumsalt/SHHS potassium salt habitual snoring nonsteroidal anti-inflammatory drug,  
    hypertension-history None
cvdishist/SHHS cardiovascular disease-history angina pectoris nonsteroidal anti-inflammatory drug, None
    habitual snoring, hypertension-history  
cvdishist/SHHS cardiovascular disease-history myocardial infarction-history hypertension-history [41]
ppmhist/SHHS pacemaker placement l-triiodothyronine nonsteroidal anti-inflammatory drug None
ppmhist/SHHS pacemaker placement nonsteroidal chronic obstructive pulmonary None
   anti-inflammatory drug disease/emphysema-history,  
    hypertension-history, habitual snoring  
depresshist/HeartBEAT depression chronic obstructive pulmonary hypercholesterolemia-history, None
   disease/emphysema - history habitual snoring, hypertension-history  
depresshist/HeartBEAT depression anxiety disorder hypercholesterolemia-history, None
    habitual snoring, hypertension-history  
dmhist/HeartBEAT diabetes mellitus-history anxiety disorder depression, habitual snoring [4245]
    hypertension-history  
dmhist/HeartBEAT diabetes mellitus-history asthma hypercholesterolemia-history, [40, 4648]
    habitual snoring, hypertension-history  
mihist/HeartBEAT myocardial infarction-history chronic obstructive pulmonary hypercholesterolemia-history, None
   disease/emphysema-history habitual snoring, hypertension-history  
mihist/HeartBEAT myocardial infarction-history depression, hypercholesterolemia-history, None
   diabetes mellitus-history hypertension-history  
triiodothy/SHHS I-triiodothyronine hypercholesterolemia habitual snoring, None
    hmg-coa reductase inhibitor  
triiodothy/SHHS I-triiodothyronine hypercholesterolemia nonsteroidal anti-inflammatory drug, None
    hmg-coa reductase inhibitor  
copdhist/HeartBEAT chronic obstructive pulmonary anxiety disorder hypercholesterolemia-history, [4851]
  disease/emphysema-history   habitual snoring, hypertension-history  
copdhist/HeartBEAT chronic obstructive pulmonary asthma hypercholesterolemia-history, None
  disease/emphysema-history   habitual snoring  
h2blocker/SHHS histamine-2 receptor antagonist angiotensin converting nonsteroidal anti-inflammatory drug, None
   enzyme inhibitor habitual-snoring, hypertension-history  
h2blocker/SHHS histamine-2 receptor antagonist hypertension-history nonsteroidal anti-inflammatory drug, None
    habitual snoring  
anixietyhist/HeartBEAT anxiety disorder habitual snoring hypercholesterolemia-history, [40, 44, 48, 52]
    depression, hypertension-history  
anixietyhist/HeartBEAT anxiety disorder myocardial infarction-history hypercholesterolemia-history, [48, 53, 54]
    depression, hypertension-history [44]
asthmahist/HeartBEAT asthma depression chronic obstructive pulmonary None
    disease/emphysema-history,  
    hypercholesterolemia-history  
asthmahist/HeartBEAT asthma hypertension-history diabetes mellitus-history [55, 56]
nsaid/HCHS nonsteroidal hypertension-history thiazide diuretic [57, 58]
  anti-inflamatory drug    
nsaid/HCHS nonsteroidal leukotriene receptor asthma, persistent wheezing None
  anti-inflamatory drug antagonist   
strokehist/SHHS stroke-history myocardial infarction-history hypertension-history [41, 59]
strokehist/SHHS stroke-history chronic obstructive pulmonary nonsteroidal anti-inflammatory drug, None
   disease/emphysema-history hypertension-history