Fig. 1
From: Heterogeneous network propagation for herb target identification
The workflow of heNetRW. Based on herb-efficacy and protein-pathway associations, cosine similarities of herb pairs and protein pairs were calculated. Then the herb-herb network and protein-protein network (Fig. 1a), whose nodes represent herbs or proteins and edges represent shared efficacies or shared pathways, were built. Given a query herb, the random walk algorithm was simulated (red line) on the heterogeneous herb-target network (Fig. 1b). By ranking the candidate targets by correlation scores, candidate targets of a given herb can be identified (Fig. 1c)