Table 1 Subject demographic characteristics and severity classifications: development data
From: Using medication utilization information to develop an asthma severity classification model
Variables | All asthma, (n = 3593) | Classified by Asthma severity, n (%) | p-value | |||
|---|---|---|---|---|---|---|
Stage 1 (n = 2253, 62.71%) | Stage 2 (n = 199, 5.54%) | Stage 3 (n = 819, 22.79%) | Stage 4 (n = 322, 8.96%) | |||
Gender, n(%) | 0.1548 | |||||
Female | 2101 (58.47) | 1285 (57.04) | 123 (61.81) | 498 (60.81) | 195 (60.56) | |
Male | 1492 (41.53) | 968 (42.96) | 76 (38.19) | 321 (39.19) | 127 (39.44) | |
Age, n(%) | <.0001 | |||||
18–34 | 880 (24.49) | 511 (22.68) | 55 (27.64) | 231 (28.21) | 83 (25.78) | |
35–44 | 609 (16.95) | 355 (15.76) | 46 (23.12) | 143 (17.46) | 65 (20.19) | |
45–54 | 660 (18.37) | 406 (18.02) | 39 (19.60) | 148 (18.07) | 67 (20.81) | |
55–64 | 619 (17.23) | 405 (17.98) | 31 (15.58) | 144 (17.58) | 39 (12.11) | |
≧65 | 825 (22.96) | 576 (25.57) | 28 (14.07) | 153 (18.68) | 68 (21.12) | |
CCI, Mean(SD) | 0.39 (0.85) | 0.41 (0.85) | 0.28 (0.84) | 0.34 (0.73) | 0.38 (1.05) | 0.0435 |
Obesity, n(%) | 10 (0.28) | 9 (0.40) | 0 (0.00) | 1 (0.12) | 0 (0.00) | 0.6141 |
Sinusitis, n(%) | 40 (1.11) | 21 (0.93) | 2 (1.01) | 15 (1.83) | 2 (0.62) | 0.1808 |
GERD, n(%) | 11 (0.31) | 10 (0.44) | 0 (0.00) | 0 (0.00) | 1 (0.31) | 0.2207 |
Medication utilization, n(%) | ||||||
ICS/LABA | 866 (24.10) | 0 (0.00) | 0 (0.00) | 660 (80.59) | 206 (63.98) | <.0001 |
ICS | 309 (8.60) | 0 (0.00) | 199 (100.0) | 89 (10.87) | 21 (6.52) | <.0001 |
OCS | 366 (10.19) | 0 (0.00) | 0 (0.00) | 203 (24.79) | 163 (50.62) | <.0001 |
SABA | 822 (22.88) | 423 (18.77) | 54 (27.14) | 267 (32.60) | 78 (24.22) | <.0001 |
SAMA | 111 (3.09) | 49 (2.17) | 5 (2.51) | 43 (5.25) | 14 (4.35) | 0.0001 |
SABA/SAMA | 155 (4.31) | 71 (3.15) | 9 (4.52) | 56 (6.84) | 19 (5.90) | <.0001 |
# of patient having acute exacerbation, n(%) | 349(9.71) | 184(8.17) | 19(9.55) | 98(11.97) | 48 (14.91) | 0.0001 |
Hospitalization | 52 (1.45) | 28 (1.24) | 4 (2.01) | 9 (1.10) | 11 (3.42) | 0.0144 |
Emergency department visit | 160(4.45) | 79(3.51) | 8(4.02) | 54(6.59) | 19(5.90) | 0.0016 |
Short-acting drug | 218(6.07) | 115(5.10) | 9(4.52) | 63(7.69) | 31(9.63) | 0.0015 |