Table 3 Designs of user-system interactions of the 20 selected pharmacogenomic CDSS
System or project name | CDSS integration | Web-based access | Active or passive CDS | Included features |
|---|---|---|---|---|
Clinical Pharmacogenomic Service (CPS) | yes | yes | active; passive | •pre-testing and post-testing alerts •reports •EHR data |
Medicine Safety Code (MSC) | no | yes | passive | •reports •search engine •others (interface to upload genetic files; printed QR codes) |
UW-PowerChart® prototype (s/n) | yes | no | active | •post-testing alerts •reports •EHR data |
CU-case series study (s/n) | no | yes | passive | •reports |
RIGHT (No.1) | yes | no | active | •pre-testing and post-testing alerts •EHR data •inbox messages |
RIGHT (No. 2) | yes | no | active | •post-testing alerts •EHR data •inbox messages |
RIGHT (No. 3) | yes | yes | active | •post-testing alerts •others (online portal for patients) |
PREDICT | yes | yes | active; passive | •pre-testing and post-testing alerts •reports •EHR data •others (online portal for patients) |
Personalized Medication Program (PMP) (No. 1) | yes | no | active; passive | •pre-testing and post-testing alerts •reports •EHR data •others (virtual PGx consult) |
Personalized Medication Program (PMP) (No. 2) | yes | no | active | •post-testing alerts •inbox messages |
PG4KDS | yes | no | active | •pre-testing and post-testing alerts •reports •EHR data •inbox messages |
GeneSight | no | yes | passive | •reports |
Genomic prescribing system (GPS) portal | no | yes | active; passive | •post-testing alerts •reports •search engine •others (virtual PGx consult) |
CLIPMERGE PGx | yes | no | active | •post-testing alerts |
Pharmacogenetics Testing Implementation Committee (PGTIC) (s/n) | yes | no | active | •pre-testing and post-testing alerts •EHR data •inbox messages |
genAP | yes | no | passive | •reports |
YouScript | no | no | passive | •reports |
TreatGx | yes | no | passive | •EHR data •inbox messages |
Coriell Personalized Medicine Collaborative (CPMC) (s/n) | no | yes | passive | •reports •inbox messages |
Warfarin Dosing prototype (s/n) | yes | no | active | •post-test alerts |