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Table 3 Designs of user-system interactions of the 20 selected pharmacogenomic CDSS

From: Integrating clinical decision support systems for pharmacogenomic testing into clinical routine - a scoping review of designs of user-system interactions in recent system development

System or project name CDSS integration Web-based access Active or passive CDS Included features
Clinical Pharmacogenomic Service (CPS) yes yes active; passive •pre-testing and post-testing alerts
•reports
•EHR data
Medicine Safety Code (MSC) no yes passive •reports
•search engine
•others (interface to upload genetic files; printed QR codes)
UW-PowerChart® prototype (s/n) yes no active •post-testing alerts
•reports
•EHR data
CU-case series study (s/n) no yes passive •reports
RIGHT (No.1) yes no active •pre-testing and post-testing alerts
•EHR data
•inbox messages
RIGHT (No. 2) yes no active •post-testing alerts
•EHR data
•inbox messages
RIGHT (No. 3) yes yes active •post-testing alerts
•others (online portal for patients)
PREDICT yes yes active; passive •pre-testing and post-testing alerts
•reports
•EHR data
•others (online portal for patients)
Personalized Medication Program (PMP) (No. 1) yes no active; passive •pre-testing and post-testing alerts
•reports
•EHR data
•others (virtual PGx consult)
Personalized Medication Program (PMP) (No. 2) yes no active •post-testing alerts
•inbox messages
PG4KDS yes no active •pre-testing and post-testing alerts
•reports
•EHR data
•inbox messages
GeneSight no yes passive •reports
Genomic prescribing system (GPS) portal no yes active; passive •post-testing alerts
•reports
•search engine
•others (virtual PGx consult)
CLIPMERGE PGx yes no active •post-testing alerts
Pharmacogenetics Testing Implementation Committee (PGTIC) (s/n) yes no active •pre-testing and post-testing alerts
•EHR data
•inbox messages
genAP yes no passive •reports
YouScript no no passive •reports
TreatGx yes no passive •EHR data
•inbox messages
Coriell Personalized Medicine Collaborative (CPMC) (s/n) no yes passive •reports
•inbox messages
Warfarin Dosing prototype (s/n) yes no active •post-test alerts
  1. Notes: “s/n” = surrogate name