Table 2 Univariable and multivariable logistic regression

 Age

1.03 (1.02, 1.03)

<0.001

1.01 (1.01, 1.017)

<0.001^†

 Gender (Male)

1.05 (0.97, 1.13)

0.254

1.02 (0.93, 1.12)

0.671

 Others

Baseline

 Chinese

1.14 (1.04, 1.25)

0.004

0.90 (0.70, 1.16)

0.407

 Indian

0.93 (0.81, 1.06)

0.300

1.18 (0.89, 1.59)

0.249

 Malay

1.16 (1.03, 1.30)

0.015

1.04 (0.79, 1.39)

0.764

 Required financial assistance using Medifund

2.64 (2.02, 3.43)

<0.001

1.49 (1.08, 2.04)

0.015^†

 Stayed in a subsidized ward during index admission

3.07 (2.72, 3.47)

<0.001

4.05 (2.54, 6.85)

<0.001^†

 ED visits (6 month before index admission)

1.47 (1.41,1.53)

<0.001

1.15 (1.09, 1.22)

<0.001^†

 Specialist Clinic visits (1 year before index admission)

1.07 (1.06, 1.07)

<0.001

1.01 (1.00, 1.02)

0.088

 Hospital admissions (1 year before index admission)

1.77 (1.70, 1.84)

<0.001

1.32 (1.26, 1.39)

<0.001^†

 Index admission was urgent

1.45 (1.32, 1.61)

<0.001

0.92 (0.73, 1.16)

0.465

 Required second line antibiotics during index admission

1.54 (1.30, 1.80)

<0.001

1.07 (0.86, 1.32)

0.534

 Required inpatient dialysis during index admission

5.30 (4.48, 6.27)

<0.001

1.72 (1.38, 2.15)

<0.001^†

 Required intravenous Furosemide 40 mg and above during index admission

2.75 (2.40, 3.14)

<0.001

1.26 (1.07, 1.48)

0.005^†

 Required isolation during index admission

1.64 (1.19, 2.22)

0.002

1.19 (0.81, 1.72)

0.375

 Length of stay of index admission

1.02 (1.01, 1.02)

<0.001

1.00 (1.00, 1.00)

0.919

 Charlson Comorbidity Index^a

1.41 (1.38, 1.42)

<0.001

1.31 (1.28, 1.33)

<0.001^†

 Stroke

0.99 (0.72, 1.34)

0.945

0.93 (0.64, 1.34)

0.712

 Metastatic Disease

1.09 (0.97, 1.24)

0.154

1.07 (0.90, 1.28)

0.43

 Non-metastatic malignancy

1.00 (0.90, 1.11)

0.973

0.96 (0.83, 1.11)

0.569

 Peripheral Vascular Disease

1.01 (0.83, 1.23)

0.904

1.10 (0.86, 1.40)

0.456

 Heart Failure or Fluid Overload

1.11 (0.98, 1.24)

0.093

1.00 (0.84,1.19)

0.978

 Pressure Ulcer

1.09 (0.88, 1.34)

0.435

1.14 (0.88,1.48)

0.307

 Thromboembolism

1.21 (1.04, 1.41)

0.014

1.21 (1.00,1.46)

0.045

 Spine Fracture

1.14 (0.90, 1.43)

0.266

1.05 (0.79, 1.38)

0.743

 Coronary Heart Disease or Myocardial Infarction

1.19 (1.07, 1.33)

0.001

1.1 (0.94, 1.29)

0.225

 Hip Fracture

0.93 (0.70, 1.22)

0.607

0.96 (0.69, 1.32)

0.795

 Atrial Fibrillation

1.16 (1.00, 1.33)

0.042

1.1 (0.92, 1.32)

0.302

 Epilepsy

1.02 (0.68, 1.48)

0.933

0.82 (0.51, 1.28)

0.394

 Parkinsonism

1.32 (0.98, 1.74)

0.062

1.43 (1.01, 2.00)

0.043

 Anxiety

0.76 (0.48, 1.16)

0.229

0.57 (0.33, 0.92)

0.028

 Bipolar Disorder

1.13 (0.51, 2.23)

0.745

1.18 (0.48, 2.65)

0.699

 Collagen Vascular Disease

0.85 (0.60, 1.17)

0.338

0.76 (0.51, 1.12)

0.175

 Dementia

0.93 (0.75, 1.16)

0.537

0.91 (0.70, 1.18)

0.498

 Hypothyroidism

0.88 (0.66, 1.15)

0.352

0.93 (0.67, 1.28)

0.681

 Chronic Kidney Disease, Stages 1–4

1.09 (0.98, 1.21)

0.095

0.97 (0.79, 1.18)

0.731

 Chronic Obstructive Pulmonary Disease

1.01 (0.79, 1.27)

0.947

1.07 (0.80,1.41)

0.648

 Osteoarthritis

0.96 (0.83,1.11)

0.582

0.90 (0.75, 1.07)

0.223

 Benign Prostatic Hypertrophy

0.94 (0.77, 1.12)

0.489

0.95 (0.76,1.18)

0.619

 Asthma

1.11 (0.89, 1.38)

0.354

1.22 (0.93, 1.59)

0.152

 Hyperlipidemia

1.09 (1.00, 1.19)

0.04

0.99 (0.85, 1.14)

0.868

 Hypertension

1.07 (0.99, 1.16)

0.085

0.96 (0.83, 1.11)

0.587

 Chronic Kidney Disease Stage 5 or End Stage Renal Failure

1.13 (1.01, 1.26)

0.035

1.03 (0.83, 1.28)

0.81

 Diabetes

1.07 (0.98, 1.17)

0.12

1.03 (0.90, 1.17)

0.71

 History of Alcoholism

1.24 (0.93, 1.64)

0.138

0.91 (0.64, 1.27)

0.582

 Treatment with anti-depressants^c

4.00 (3.60, 4.44)

<0.001

2.33 (2.06, 2.64)

<0.001^†