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Table 2 Validity of EMRa definitions for liver disease

From: Development and validation of method for defining conditions using Chinese electronic medical record

Variable

Sensitivity % (95 % CIb)

Specificity % (95 % CI)

PPVc % (95 % CI)

NPVd % (95 % CI)

Liver disease

 Primary liver cancer

100.0 (96.2, 100.0)

98.9 (97.1, 99.7)

96.0 (90.1, 98.9)

100.0 (99.0, 100.0)

 Hepatitis B

88.2 (82.9, 92.3)

98.8 (96.5, 99.8)

98.4 (95.3, 99.7)

91.0 (87.0, 94.2)

 Hepatitis C

82.5 (67.2, 92.7)

99.5 (98.3, 99.9)

94.3 (80.8, 99.3)

98.3 (96.6, 99.3)

 Fatty liver

100.0 (81.5, 100.0)

100.0 (99.2, 100.0)

100.0 (81.5, 100.0)

100.0 (99.2, 100.0)

 Alcoholic liver disease

100.0 (89.1, 100.0)

98.3 (96.6, 99.3)

82.1 (66.5, 92.5)

100.0 (99.1, 100.0)

 Cirrhosis

78.9 (71.4, 85.2)

98.4 (96.2, 99.5)

95.9 (90.6, 98.6)

90.6 (86.9, 93.5)

Liver disease severity

 Spontaneous bacterial peritonitis

91.0 (81.5, 96.6)

99.7 (98.6, 100.0)

98.4 (91.3, 100.0)

98.5 (96.7, 99.4)

 Variceal hemorrhage

95.0 (75.1, 99.9)

98.8 (97.3, 99.6)

79.2 (57.9, 92.9)

99.8 (98.7, 100.0)

 Hepatorenal syndrome

100.0 (47.8, 100.0)

100.0 (99.2, 100.0)

100.0 (47.8, 100.0)

100.0 (99.2, 100.0)

 Hepatic encephalopathy

100.0 (91.2, 100.0)

100.0 (99.1, 100.0)

100.0 (91.2, 100.0)

100.0 (99.1, 100.0)

 Ascites

95.2 (89.8, 98.2)

99.1 (97.3, 99.8)

97.5 (92.9, 99.5)

98.2 (96.1, 99.3)

  1. aEMR electronic medical records; bCI confidence interval; cPPV positive predictive value; dNPV negative predictive value