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Table 4 Net Benefit for ALSS for All ACLF Patients or According to LRM, Using a Threshold of Pt

From: Logistic regression model can reduce unnecessary artificial liver support in hepatitis B virus-associated acute-on-chronic liver failure: decision curve analysis

Pt (%)

Net Benefit

Advantage of LRM-guided ALSS

ALSS for All

LRM-guided ALSS

Net Benefit

Reduction in Avoidable ALSS per 100 Patients

16

0.430

0.430

0

0

20

0.402

0.414

0.012

5

30

0.317

0.365

0.048

11

40

0.203

0.299

0.096

14

50

0.043

0.207

0.164

16

60

−0.197

0.069

0.266

18

64

−0.329

−0.008

0.321

18

  1. Note: The reduction in the number of unnecessary ALSS per 100 patients is calculated as follows: (net benefit of the model – net benefit of treat all)/[Pt/(1 – Pt)] × 100
  2. ALSS artificial liver support system, ACLF, acute-on-chronic liver failure, LRM logistic regression model, Pt threshold probability of risk