Table 1 Infrastructure components required for meeting CDS prerequisites

Computer-processable medical knowledge

Centrally managed repositories of computer-processable medical knowledge

Most healthcare organizations lack the resources to create and maintain required knowledge repositories for themselves

Standardization of CDS information provided for specific aspects of genomic medicine

All knowledge resources should provide consistent CDS information for common aspects of genomic medicine

Computer-interpretable patient data

Standardized representation of patient data

Variable representation of patient data makes CDS resources difficult to re-use across different settings

Generation of patient-specific advice using knowledge and patient data

Standard approaches for leveraging computer-processable medical knowledge

Disparate approaches to integrating knowledge resources make such resources difficult to re-use across different settings

Standard approach for locating and retrieving patient data

Patients receive care across institutional boundaries