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Table 1 Major cardiovascular risk models and their inputs and outputs.

From: Construction of an odds model of coronary heart disease using published information: the Cardiovascular Health Improvement Model (CHIME)

Risk equation Risk factors included Risks evaluated
Framingham (Anderson)[7] Age, gender, smoking, blood pressure (BP), total cholesterol (TC)/high density lipoprotein (HDL) ratio, diabetes, left ventricular hypertrophy (LVH) 4 to 12-year risk of CHD events and death, all CVD events and death, all cerebrovascular events, myocardial infarction events.
Framingham (D'Agostino)[12] Age, gender, smoking, BP, TC/HDL ratio, alcohol, existing CVD, menopausal status (women), triglycerides in women 2-year risk of CHD events.
Whitehall equation[32] Age, gender, TC, BP, cigarettes per day 5 or 10-year risk of CHD event.
Systematic Coronary Risk Evaluation (SCORE)[6] Age, gender, smoking, BP, TC and residence in a 'high' or 'low' risk country. 10-year risk of death from CHD or CVD.
Munster Heart Study (PROCAM)[33] Age, smoking, BP, low density lipoprotein (LDL), HDL, triglycerides, gamma glutamyl transferase (γGT), diabetes, existing angina, family history Major coronary event.
Ethrisk[11] Age, gender, smoking, BP, TC/HDL ratio, diabetes, LVH and ethnic group 10-year risk of CHD event.
ASSIGN[10] Age, gender, cigarettes per day, systolic BP, TC/HDL ratio, family history, SIMDSC10 deprivation score 10-year risk of CVD.
QRisk[9] Age, gender, smoking, BP, TC/HDL, body mass index (BMI), family history, treatment with antihypertensive drugs, Townsend area deprivation score. 10-year risk of CVD events.