Algorithm

median (mean) AUC_{0–1}

median (mean) AUC_{0–0.01} ^{†}

median (mean) AUC_{0–0.005} ^{‡}

median (mean) WtAUC_{0–1}

median (mean) WtAUC_{0–0.01} ^{‡}


EARS C1

0.995 (0.989)

0.0011 (0.0019)

0.0004 (0.0015)

0.959 (0.968)

<0.0001 (0.0008)

EARS C2

0.996 (0.990)

0.0017 (0.0026)

0.0002 (0.0016)

0.994 (0.978)

0.0002 (0.0013)

EARS C3

0.996 (0.993)

0.0061 (0.0059)

0.0011 (0.0022)

0.991 (0.980)

0.0011 (0.0033)

NBC 7day

1.0 (0.998)

0.0095 (0.0081)

0.0049 (0.0040)

0.990 (0.979)

<0.0001 (0.0032)

NBC 14day

1.0 (0.999)

0.0099 (0.0088)

0.0049 (0.0040)

0.988 (0.981)

<0.0001 (0.0026)

NBC 28day

1.0 (1.0)

0.0095 (0.0092)

0.0049 (0.0047)

0.990 (0.983)

0.0014 (0.0032)

NBC 56day

1.0 (0.999)

0.0095 (0.0088)

0.0042 (0.0036)

0.977 (0.928)

<0.0001 (0.0018)

pvalue^{¥}

<0.0001

<0.0001

<0.0001

0.046

0.006


^{†}Evaluated at a false alarm rate ≤ 0.01

^{‡}Evaluated at a false alarm rate ≤ 0.005

^{¥}Friedman rank sum test
 WtAUC: Weighted AUC using a reference value of 7 days for valid detection
 EARS: Early Aberration Reporting System
 NBC: Negative binomial cusum with an out of control state defined as 2 standard deviations greater than the mean