A decision-analytic approach to define poor prognosis patients: a case study for non-seminomatous germ cell cancer patients

Table 1 Survival and early treatment related death in non-seminomatous germ cell cancer patients treated with high-dose (HD) or standard-dose (SD) chemotherapy

Reference	Treatment	Year treatment	N	S_OVERALL	F-up	R_OV-MORT	Early toxic death²	R_C-MORT	R_{C-MORT 10 yrs}
Hinton et al. [13]	SD	1987–1992	181	60%	5	40%	3%	37%	44%
Sonneveld et al. [17]	SD	1987–1996	22	66%¹	10	34%	NA	31%	31%
Schmoll et al. [5]	HD	1993–1999	182	73%¹	5	27%	4%	23%	28%

S_OVERALL = Overall survival at year of follow-up
F-up = follow-up in years
R_OV-MORT = Risk of overall mortality at year of follow-up
R_C-MORT = Risk of cancer mortality at year of follow-up
R_{C-MORT 10 yrs} = Risk of cancer mortality 10 year after treatment
1 disease specific survival
2 early toxic death [5]: neutropenic infections (decreased white blood cells) and septic multi-organ failure. HD toxic death: any death occurring within 100 days from grafting and not directly related to the disease itself.

ISSN: 1472-6947