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Table 1 Survival and early treatment related death in non-seminomatous germ cell cancer patients treated with high-dose (HD) or standard-dose (SD) chemotherapy

From: A decision-analytic approach to define poor prognosis patients: a case study for non-seminomatous germ cell cancer patients

Reference Treatment Year treatment N SOVERALL F-up ROV-MORT Early toxic death2 RC-MORT RC-MORT 10 yrs
Hinton et al. [13] SD 1987–1992 181 60% 5 40% 3% 37% 44%
Sonneveld et al. [17] SD 1987–1996 22 66%1 10 34% NA 31% 31%
Schmoll et al. [5] HD 1993–1999 182 73%1 5 27% 4% 23% 28%
  1. SOVERALL = Overall survival at year of follow-up
  2. F-up = follow-up in years
  3. ROV-MORT = Risk of overall mortality at year of follow-up
  4. RC-MORT = Risk of cancer mortality at year of follow-up
  5. RC-MORT 10 yrs = Risk of cancer mortality 10 year after treatment
  6. 1 disease specific survival
  7. 2 early toxic death [5]: neutropenic infections (decreased white blood cells) and septic multi-organ failure. HD toxic death: any death occurring within 100 days from grafting and not directly related to the disease itself.