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Table 2 Characteristics of children included born either SGA (a and b) or preterm (c and d). The data is presented for the Auxological model.

From: Models predicting the growth response to growth hormone treatment in short children independent of GH status, birth size and gestational age

  a. Model group b. Validation group
Variables Mean SD Min Max N Mean SD Min Max N
At birth           
Gestational age (weeks) 39.4 1.3 37 42 144 39.2 1.5 37 42 34
   Height SDS -2.58 0.93 -5.8 -0.5 144 -2.55 0.84 -5.4 -0.9 34
   Weight SDS -2.25 0.89 -4.5 0.4 144 -2.19 0.80 -4.4 -0.6 34
Pretreatment           
Δheight SDS during pretreat yr 0.02 0.19 -0.5 0.6 134 0.03 0.19 -0.3 0.7 32
   GHmax of GH-profile 47.8 27.8 11.7 146.9 77 38.5 23.6 14.2 98.1 18
   GHmax during AITT 34.6 26.2 3.0 160 133 24.3 17.8 5.9 76.1 28
At GH start           
   SEX (min = girls, max = boys)    34 110 144    14 20 34
   Age (yrs) 8.1 2.51 3.1 13.3 144 7.8 2.20 3.2 11.4 34
   Height SDS -3.04 0.65 -4.8 -1.5 144 -2.94 0.54 -4.2 -2.0 34
   Weight SDS -2.79 1.05 -6.2 1.6 144 -2.71 0.98 -4.9 0.0 34
   Father height SDS -1.07 1.17 -4.9 1.9 144 -0.93 1.00 -2.8 1.7 34
   Mother height SDS -1.39 1.09 -3.6 1.2 144 -1.28 0.97 -3.1 1.0 34
   Diff SDS -2.29 0.82 -4.6 -0.4 144 -2.27 0.83 -5.1 -0.8 34
   IGF SDS -0.81 1.46 -7.4 3.0 87 -1.02 1.64 -4.0 2.7 25
   Leptin (ng/mL) 3.65 3.24 1.2 27.8 92 3.12 1.05 1.7 5.3 25
During treatment           
   GH dose (IU/kg/day) 0.11 0.03 0.07 0.22 144 0.11 0.02 0.09 0.18 34
   Change in height SDS 1st yr 0.7 0.28 0.1 2.0 144 0.64 0.19 0.1 1.0 34
   Change in height SDS two yrs 1.1 0.41 0.2 3.0 108 1.03 0.32 0.4 1.9 26
  c. Model group d. Validation group
At birth           
Gestational age (weeks) 34.4 1.7 30 36 36 34.4 2.5 27 36 11
   Height SDS -2.57 1.96 -8.1 0.7 36 -1.75 1.55 -4.0 1.4 11
   Weight SDS -2.18 1.66 -6.1 0.7 36 -1.78 1.6 -3.5 1.8 11
Pretreatment           
Δheight SDS during pretreat yr -0.05 0.22 -0.4 0.5 32 0.03 0.1 -0.1 0.2 11
   GHmax of GH-profile 44.1 25.9 14.3 134 22 28.6 10.5 15.4 48.9 10
   GHmax during AITT 28.6 15.1 8.5 70.4 33 38.3 17.4 8.8 63.8 10
At GH start           
   SEX (min = girls, max = boys)    7 29 36    5 6 11
   Age (yrs) 7.89 2.91 2.8 14.6 36 6.69 1.32 4.8 9.0 11
   Height SDS -2.84 0.59 -4.1 -1.5 36 -2.61 0.36 -3.2 -2.0 11
   Weight SDS -3.01 0.89 -5.2 -0.7 36 -2.40 1.14 -5.2 -0.2 11
   Father height SDS -1.16 0.88 -3.4 0.4 36 -0.40 1.21 -2.8 1.3 11
   Mother height SDS -1.02 0.89 -3.2 1.2 36 -0.68 1.26 -3.4 1.6 11
   Diff SDS -2.2 0.72 -3.5 -1.0 36 -2.36 0.52 -3.3 -1.3 11
   IGF SDS -1.54 1.19 -5.4 0.2 26 -1.12 1.41 -3.3 0.7 11
   Leptin (ng/mL) 3.25 1.16 2.1 7.1 21 3.96 1.73 2.5 8 9
During treatment           
   GH dose (IU/kg/day) 0.11 0.03 0.08 0.19 36 0.14 0.03 0.10 0.18 11
   Change in height SDS 1st yr 0.68 0.25 0.4 1.2 36 0.71 0.16 0.5 1.0 11
   Change in height SDS two yrs 1.1 0.39 0.6 2.2 28 1.18 0.16 0.9 1.4 8
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