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Table 4 The E-M iteration results for a Three-state Markov model taking missing data on interval cases into account

From: Estimation of progression of multi-state chronic disease using the Markov model and prevalence pool concept

 

Parameter

Iteration

λ 1 (95% CI

λ 2 (95% CI)

Overall

  

0

0.0103

0.1089

1

0.0104

0.1107

5

0.0107

0.1135

6

0.0107

0.1135

 

(0.0064~0.0180)

(0.0786~0.1639)

≥ 50 yrs

  

0

0.0151

0.1176

1

0.0151

0.0926

11

0.0151

0.0926

12

0.0151

0.0926

 

(0.0078~0.0294)

(0.0579~0.1482)

< 50 yrs

  

0

0.0075

0.1176

1

0.0075

0.1934

15

0.0075

0.1933

16

0.0075

0.1933

 

(0.0029~0.0192)

(0.0993~0.3761)

  1. λ 1:normal → asymptomatic. λ 2:asymptomatic → symptomatic