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Table 3 The E-M iteration results for a Three-state Markov model taking age as a covariate in proportional hazard regression model

From: Estimation of progression of multi-state chronic disease using the Markov model and prevalence pool concept

 

Parameter

Iteration

β

(≥ 50 yrs)

(< 50 yrs)

 

(95% CI)

λ 11

λ 21

λ 12

λ 22

-----

---------

----------

0.0926

----------

0.1934

1

0.7008

0.0151

0.0926

0.0075

0.1933

2

0.7008

0.0151

0.0926

0.0075

0.1933

3

0.7008

0.0151

0.0926

0.0075

0.1933

 

(0.0681~7.2133)

    
  1. λ 11 &λ 12:normal → asymptomatic.
  2. λ 21 &λ 22:asymptomatic → symptomatic