Figure 1From: Context-based resolution of semantic conflicts in biological pathwaysDual function of TAK1. In mouse embryonic fibroblasts (MEFs), TAK1-TAB1 complex activates NF-κB signaling pathway to protect cells from apoptosis. However, in neutrophils, TAK1 binding prevents TAB1 from activating NF-κB signaling pathway, resulting in cell apoptosis.Back to article page