Table 2 Characteristics of the study population
Variable | Median (interquartile range) or N (%) | |||||
|---|---|---|---|---|---|---|
| Â | BRCA1 | BRCA2 | ||||
|  | Menopause (n = 200) | Ovulating (n = 113) | All (n = 548)* | Menopause (n = 195) | Ovulating (n = 93) | All (n = 523)* |
Year of birth | 1955 (1946-1962) | 1963 (1952-1979) | 1959 (1948-1969) | 1952 (1944-1959) | 1963 (1952-1971) | 1957 (1947-1966) |
Manchester score | 32 (22.5-40) | 28 (20-38) | 29 (20-40.75) | 26 (20-35) | 27 (20-36) | 26 (20-35) |
BMI | 24.07 (22.34-28.18) | 22.52 (21.39-26.71) | 23.7 (21.6475-27.3125) | 25.12 (22.52-28.565) | 24.225 (21.975-27.02) | 24.84 (22.355-28.305) |
Parity | 2 (2-3) | 1 (0-2) | 2 (1-3) | 2 (0-9) | 2 (0-9) | 2 (0-9) |
Age of menarche | 13 (12-14.25) | 13 (12-14) | 13 (12-14) | 13 (12-14) | 13 (12-14) | 13 (12-14) |
Age of menopause | 43 (38-46) | 44 (40-48)** | 43 (39-47)** | 45 (40.5-48.5) | 45 (39.5-49.5)** | 45 (40-49)** |
Age of full-term pregnancy | 24 (21-28) | 23 (20-26.25) | 24 (21-28) | 24 (21-28) | 23 (20.25-27) | 24 (21-28) |
Oral contraception usage | 5 (1-10) | 7 (2.75-11) | 5 (2-10) | 5 (1-10) | 5 (1-10) | 5 (1-10) |
Genetic predisposition score | 0.98 (0.70-1.29) | 0.95 (0.63-1.17) | 0.95 (0.67-1.27) | 0.83 (0.63-1.17) | 1.17 (0.77-1.62) | 0.90 (0.68- 1.33) |
Oophorectomy | 70 (35%) | 0 (0%) | 71 (12.96%) | 88 (45.13%) | 0 (0%) | 102 (19.50%) |
Mastectomy | 35 (17.5%) | 7 (6.19%) | 49 (8.94%) | 17 (9.74%) | 0 (0%) | 17 (3.25%) |
Time of observation (years) | 48.04 (42.74-53.76) | 30.83 (28.0-38.90) | 41.26 (35.83-49.38) | 50.68 (44.77-57.70) | 33.66 (29.13-42.49) | 44.37 (38.02-51.78) |
No. of events | 92 (46.00%) | 88 (77.88%) | 321 (58.58%) | 105 (53.85%) | 72 (77.42%) | 323 (61.76%) |