Table 3 Diagnostic performance of prediction models in the internal and external validation groups
| Â | AUC (95% CI) | Accuracy (%) (95% CI) | Sensitivity (%) (95% CI) | Specificity (%) (95% CI) | PPV (%) | NPV (%) | |
|---|---|---|---|---|---|---|---|
(A) Internal validation group (N = 163) | |||||||
|  | LASSO†| 0.81 (0.74-0.86) | 73.6 (66.0-80.1) | 77.4 (70.1-83.5) | 72.7 (65.1-79.3) | 40.0 | 93.2 |
|  | LR-BS†| 0.79 (0.72-0.85) | 64.4* (56.5-71.7) | 83.9 (77.1-89.1) | 59.8 (51.9-67.4) | 32.9 | 94.0 |
| Â | HbA1c | 0.69* (0.62-0.76) | 66.3* (58.4-73.4) | 77.4 (70.1-83.5) | 63.6 (55.7-70.9) | 33.3 | 92.3 |
| Â | FPG | 0.54* (0.46-0.62) | 57.7* (49.7-65.3) | 61.3 (53.3-68.7) | 56.8 (48.8-64.5) | 25.0 | 86.2 |
| Â | Duration of diabetes | 0.72* (0.66-0.79) | 57.1* (49.1-64.7) | 87.1 (80.7-91.7) | 50.0 (42.1-57.9) | 29.0 | 94.3 |
(B) External validation group (N = 562) | |||||||
|  | LASSO†| 0.82 (0.78-0.85) | 75.2 (71.3-78.7) | 72.1 (68.0-75.8) | 76.0 (72.1-79.5) | 43.7 | 91.3 |
|  | LR-BS†| 0.79 (0.75-0.83) | 68.7* (64.6-72.6) | 82.0 (78.4-85.1) | 65.3 (61.1-69.3) | 37.9 | 93.3 |
| Â | HbA1c | 0.69* (0.65-0.73) | 63.7* (59.5-67.7) | 70.3 (66.2-74.1) | 62.0 (57.7-66.1) | 32.4 | 89.0 |
| Â | FPG | 0.65* (0.60-0.69) | 68.3* (64.1-72.0) | 57.7 (53.4-61.8) | 73.4 (69.4-77.1) | 36.0 | 87.0 |
| Â | Duration of diabetes | 0.73* (0.69-0.77) | 69.6* (66.5-74.3) | 64.9 (60.7-68.9) | 72.0 (68.0-75.7) | 37.5 | 88.8 |