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Table 3 Differences in the serological parameters between IgAN and non-IgAN

From: A novel differential diagnostic model based on multiple biological parameters for immunoglobulin A nephropathy

Parameter Mean ± SD P-value
IgAN Non-IgAN
FIBa 3.63 ± 1.00 5.00 ± 2.60 0.000
sIgGa 1018.5 ± 307.0 858.2 ± 352.7 0.020
TP b 66.2 ± 9.5 57.3 ± 12.7 0.000
ALB b 39.1 ± 6.5 31.7 ± 9.7 0.000
Ca b 2.22 ± 0.15 2.09 ± 0.18 0.000
D2a 0.70 ± 1.26 1.46 ± 2.99 0.019
sIgA a 331.3 ± 103.9 241.5 ± 102.3 0.000
CHa 4.84 ± 1.24 6.38 ± 2.79 0.002
DBa 3.1 ± 1.8 2.4 ± 1.3 0.029
LDLa 2.98 ± 1.00 4.14 ± 2.23 0.003
CA153a 11.9 ± 5.2 14.9 ± 7.7 0.038
TGa 1.7 ± 1.1 2.1 ± 1.0 0.013
ALPa 68.8 ± 40.2 81.0 ± 50.3 0.015
CA199a 12.0 ± 8.7 18.8 ± 20.3 0.046
UN a 6.6 ± 3.1 6.1 ± 3.4 0.048
  1. a P < 0.05 via Mann–Whitney U-test; b P < 0.05 via t-test
  2. Abbreviations: FIB, fibrinogen; sIgG, serum immunoglobulin G; TP, total protein; ALB, albumin; Ca, calcium; D2, D-dimer; sIgA, serum immunoglobulin A; CH, total cholesterol; DB, direct bilirubin; LDL, low density lipoprotein; CA153, carbohydrate antigen 15–3; TG, triglyceride; ALP, alkaline phosphatase; CA199, carbohydrate antigen; UN, urea.