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Table 3 Differences in the serological parameters between IgAN and non-IgAN

From: A novel differential diagnostic model based on multiple biological parameters for immunoglobulin A nephropathy

Parameter

Mean ± SD

P-value

IgAN

Non-IgAN

FIBa

3.63 ± 1.00

5.00 ± 2.60

0.000

sIgGa

1018.5 ± 307.0

858.2 ± 352.7

0.020

TP b

66.2 ± 9.5

57.3 ± 12.7

0.000

ALB b

39.1 ± 6.5

31.7 ± 9.7

0.000

Ca b

2.22 ± 0.15

2.09 ± 0.18

0.000

D2a

0.70 ± 1.26

1.46 ± 2.99

0.019

sIgA a

331.3 ± 103.9

241.5 ± 102.3

0.000

CHa

4.84 ± 1.24

6.38 ± 2.79

0.002

DBa

3.1 ± 1.8

2.4 ± 1.3

0.029

LDLa

2.98 ± 1.00

4.14 ± 2.23

0.003

CA153a

11.9 ± 5.2

14.9 ± 7.7

0.038

TGa

1.7 ± 1.1

2.1 ± 1.0

0.013

ALPa

68.8 ± 40.2

81.0 ± 50.3

0.015

CA199a

12.0 ± 8.7

18.8 ± 20.3

0.046

UN a

6.6 ± 3.1

6.1 ± 3.4

0.048

  1. a P < 0.05 via Mann–Whitney U-test; b P < 0.05 via t-test
  2. Abbreviations: FIB, fibrinogen; sIgG, serum immunoglobulin G; TP, total protein; ALB, albumin; Ca, calcium; D2, D-dimer; sIgA, serum immunoglobulin A; CH, total cholesterol; DB, direct bilirubin; LDL, low density lipoprotein; CA153, carbohydrate antigen 15–3; TG, triglyceride; ALP, alkaline phosphatase; CA199, carbohydrate antigen; UN, urea.