Table 3 Proof-of-concept searches showing the number of relevant articles retrieved with and without glomerular disease filter
Clinical Question* | Physician search alone | Physician search with the high-sensitivity filter | Physician search with the high-specificity filter | |||
|---|---|---|---|---|---|---|
| Â | Number of non-relevant articles retrieved | Number of relevant articles retrieved | Number of non-relevant articles retrieved | Number of relevant articles retrieved | Number of non-relevant articles retrieved | Number of elevant articles retrieved |
What are the efficacy and safety of mycophenolate mofetil (MMF) and cyclophosphamide (CYC) in the treatment of proliferative lupus glomerulonephritis (GN)? (7 relevant articles) [29] | 2006 | 7 | 1721 | 7 | 1080 | 7 |
Is immunosuppressive treatment effective and safe in the treatment of idiopathic membranous nephropathy (IMN) in adults with nephrotic syndrome? (15 relevant articles) [30] | 87500 | 15 | 3231 | 15 | 2687 | 15 |
Does corticosteroid therapy ameliorate the acute manifestations of Henoch-Schonlein purpura or mitigate renal injury? (15 relevant articles) [31] | 393 | 5 | 68 | 5 | 65 | 5 |
What are the benefits and harms of different interventions for the treatment of renal vasculitis in adults? (13 relevant articles) [32] | 34741 | 8 | 8455 | 8 | 5923 | 8 |
What is the effect of a low-protein diet (LPD) on renal function in patients with type 1 or 2 diabetic renal diseases? (8 relevant articles) [33] | 868 | 7 | 207 | 7 | 180 | 6 |
What are the benefits and harms of interventions for the nephrotic syndrome in adults caused by minimal change disease? (3 relevant articles) [28] | 4662 | 3 | 1236 | 3 | 1203 | 3 |