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Table 5 Statistical significance of cut-off points determined using the C5.0 decision tree algorithm (for univariate analysis)

From: A hybrid decision support model to discover informative knowledge in diagnosing acute appendicitis

Variables

OR (95% CI)

p value

Level 0 (root node)

  

LYMP ≤ 20.2% or > 20.2%

12.527 (6.335-24.770)

0.000

Level 1

  

Urine glucose (negative)

0.036 (0.005-0.270)

0.001

Urine glucose (positive)

27.645 (3.709-206.043)

0.001

BASO ≤ 1.1%

9.333 (1.169-74.489)

0.035

BASO > 1.1%

0.107 (0.013-0.8555)

0.035

Level 2*

  

Abdominal pain

4.487 (2.556-7.878)

0.000

LUQ or LLQ or RUQ pain

4.594 (0.929-22.712)

0.062

APA pain

1.087 (0.237-4.994)

0.914

RLQ pain

7.447 (3.274-16.938)

0.000

Lower abdominal pain

6.058 (1.273-28.826)

0.024

Upper abdominal pain

2.465 (0.099-61.267)

0.582

WBC ≤ 6.2 × 103/μL or > 6.2 × 103/μL

25.000 (0.341-1831.738)

0.142

Level 3

  

Bilirubin (T) ≤ 1.0 mg/dL or > 1.0 mg/dL

6.576 (2.791-15.493)

0.000

WBC ≤ 14.37 × 103/μL or > 14.37 × 103/μL

63.000 (0.982-4042.374)

0.051

Cl ≤ 104 mmol/L

9.197 (0.499-169.573)

0.136

Cl > 104 mmol/L

0.109 (0.006-2.005)

0.136

Bilirubin (D) ≤ 0.4 mg/dL or > 0.4 mg/dL

95.000 (1.482-6088.126)

0.032

Level 4

  

Amylase (T) ≤ 58 U/L

0.033 (0.002-0.584)

0.020

Amylase (T) > 58 U/L

29.881 (1.1711-521.765)

0.020

APTT ≤ 22.6 s or > 22.6 s

37.800 (1.829-781.085)

0.019

Urine ketone (negative)

0.667 (0.113-3.919)

0.654

Urine ketone (positive)

1.500 (0.255-8.817)

0.654

Level 5

  

MONO ≤ 2.4% or > 2.4%

19.667 (1.022-378.446)

0.048

NEUT ≤ 84%

0.055 (0.003-1.051)

0.054

NEUT > 84%

18.103 (0.951-344.559)

0.054

MONO ≤ 3.6% or > 3.6%

29.000 (1.413-595.209)

0.029

Level 6

  

EOS ≤ 2.4%

0.077 (0.004-1.426)

0.085

EOS > 2.4%

13.047 (0.701-242.739)

0.085

LYMP ≤ 13.8% or > 13.8%

49.286 (2.214-1097.056)

0.014

EOS ≤ 1.5% or > 1.5%

47.667 (1.597-1422.784)

0.026

Level 7

  

Urine ketone (negative or positive)

1.932 (0.423-8.814)

0.395

Bilirubin (D) ≤ 0.3 mg/dL or > 0.3 mg/dL

25.000 (0.750-832.997)

0.072

Level 8

  

Glucose ≤ 124 mg/dL or > 124 mg/dL

25.706 (1.307-505.514)

0.033

BASO ≤ 0.4% or > 0.4%

12.600 (0.446-356.388)

0.137

Level 9

  

Cl ≤ 107 mmol/L or > 107 mmol/L

18.667 (1.563-222.937)

0.021

Level 10

  

RBC ≤ 4.14 × 103/μL or > 4.14 × 103/μL

25.000 (0.750-832.997)

0.072

  1. * LUQ, left upper quadrant; LLQ, left lower quadrant; RUQ, right upper quadrant; PA, periumbilical area; RLQ, right lower quadrant