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Table 1 Different RAEs and their characteristics *

From: A study of diverse clinical decision support rule authoring environments and requirements for integration

RAE

Setting

Clinical System

Scope

Est. # of Rulesξ

REMINDER RULE EDITORS

Reminder Editor (1st generation)

Ambulatory

Standalone

Used by KEs for entering and editing reminder rules

356

Reminder Editor (2nd generation)

Ambulatory

Embedded in an ambulatory EHR

Used by KEs for entering and editing reminder rules

356

Enterprise Rule Services (3rd generation)

Ambulatory

Standalone; service-oriented

Used by KEs for entering and editing diverse clinical decision support rules

120

MEDICATION RULE EDITORS

Drug-Drug Interaction (DDI) Editor

Ambulatory and inpatient

Standalone; web-based application

Used by KEs for entering and editing DDI rules

2800

Renal Drug Dosing (Nephros)

Ambulatory and inpatient

Embedded in an inpatient CIS. CDS rules are maintained in a specific EHR, but are used at the enterprise level by other systems

Used by KEs for entering and editing rules to offer substitute drugs or adjust dose or frequency list for a drug for renally impaired patients (e.g., based on a particular Creatinine value)

352

Geriatric Drug Dosing (Gerios)

Ambulatory and inpatient

Embedded in an inpatient CIS. CDS rules are maintained in a specific EHR, but are used at the enterprise level by other systems

Used by KEs for entering and editing rules to offer substitute drugs or adjust dose or frequency list for a drug for geriatric patients, based on a particular age value

244

Neonate Pediatric Drug Dosing

Inpatient

Embedded in a medication concept editor

Used by KEs for entering and editing rules to offer substitute drugs or adjust dose or frequency list for a drug for pediatric patients

1000

Food Drug Interaction

Ambulatory and inpatient

Embedded in a medication concept editor

Used by KEs for entering and editing FDI rules

200

Duplicate Therapy

Ambulatory and inpatient

Standalone; web-based application

Used by KEs for entering and editing rules to detect potential drug duplications

190

Medication Rule Editor

Ambulatory

Embedded in an ambulatory EHR

Maintains its own set of medication rules, including drug-disease, drug-pregnancy, drug lab, drug-group, group-group interactions

2300

  1. *The platform of Medication Rule Editors is largely based on Cache and Visual Basic. The platform of Reminder Rule Editors varies. 1st generation is Microsoft Access-based, 2nd generation is Cache based, and 3rd generation is Java-based.
  2. ξMedication rule editors as of February 2009, Reminder rule editors as of February 2012.